A new century of Alzheimer's disease research
...to attack Aâ42, believed to be the most vulnerable target -- the Achilles’ heel -- of Alzheimer’s disease. ...be safer. (NSAIDs reduce inflammation because they target enzymes that are known as cyclooxygenases or COX, and classic NSAIDs, such as ibuprofen and indometh...White Blood Cell Booster May Help Cancer Patients Avoid Deadly Complications
...Comprehensive Cancer Center. "Chemotherapy drugs target cancer cells, but they can affect healthy cells as well, including infection-fighting white blood cells," said Nicole M. Kuderer, M.D., a hematology-oncology fellow at Duke and lead author on the publication. "When patients' white blood cell counts d...Structure of TB Enzyme Points the Way to New Drugs: Study
...e that causes tuberculosis would make a promising target for new drugs to combat the deadly infectious dise...zyme, protein kinase G (PknG), as a promising drug target back in 2004. At the time, they said that the protein is the secret weapon that enables the TB bug...Annual Tobacco-related Deaths to Reach 8.3 Million by 2030
...llion by 2030 as multinational cigarette companies target the region's huge and still undeveloped market and transnational crime that takes advantage of smuggling opportunities, said Bettcher. But the WHO is convinced that tighter laws on the tobacco industry could save 200 million lives by 2050, he said....Electric Field Therapy to Zap Cancerous Tumours
...r rate than most normal cells, making them a prime target for TTF. Treatments such as chemotherapy and radiation also target rapidly dividing cells, but they can cause severe side effects by damaging the intestinal lining and...FDA Extends GRAS Approval Listex to All Food Products
...es are harmless to humans, animals and plants, and target only bacterial cells. They are extremely specific ...eria they recognize. The LISTEX(TM) bacteriophages target only Listeria bacteria (leaving desirable bacteria in place), and are easy to apply in production pr......d Fuller. We hope IGFBP2 will provide an effective target for treatment of this devastating disease. Sarah Dunlap, a student in the Graduate School of Biomedical Sciences jointly operated by M. D. Anderson and The University of Texas Health Science Center at Houston, is the reports first author. Other Ful...Skin Cancer can Be Triggered by P53 Mutation
...CC. Future studies will hopefully discover ways to target these mutations for therapeutic purposes. A link between skin inflammation and SCC formation was first reported in the 19th century. In the second of these 2 new JCI studies, Robert Nibbs, Gerard Graham, and colleagues from Glasgow University show ...... biology and we know the players, it's possible to target with specific drugs." Childhood asthma treatments are heavily focused on allergic responses, since most children with asthma also have many allergies. The discovery of a so-called 'asthma gene' would provide a new set of mechanisms to try and modify...Kids With Crohn's Disease are at Ease Now
...ors and antibiotics. Biologic agents selectively target key inflammatory processes involved in the development of a disease in this case infliximab blocks the bodys inflammation response. Its side-effects can include upper respiratory infections and other potentially serious reactions. The Al and Heidi ...... developed the ClosTron knock out system which can target specific genes in C. diff and other clostridial sp...by the spores of harmless clostridial species that target the cancer tissue; (ii) more effectively controlling the food borne bacterium C. botulinum, and (iii...Contraceptive Spray Shows Positive Clinical Trial Result
...trations of Nestorone and Ethinyl Estradiol in the target range expected to provide effective contraception....ery of Nestorone, with blood concentrations in the target range that is expected to provide effective contraception. The spray was well tolerated, with no ser...Irish Outsourcing of Smear Test may Result in Cervical Cancer Being Undetected
...site. "As a result the HSE is now achieving its target whereby no woman should be waiting more than four ...said in a statement that the US handling meant its target of results back to women within four weeks could now be met....Scientists Destroy Cancer Cells Using Electric Pulses
...t kills the cells, Davalos and Rubinsky used it to target cancer cells. "IRE removes tumours by irreversibly opening tumour cells through a series of short intense electric pulses from small electrodes placed in or around the body," said Davalos, who is the 2006 recipient of the Hispanic Engineer Nationa...Gadrasil Could Prove Effective in Men too
...the new frontier of cancer meds. Gardasil does not target cancers directly but the viruses that can lead to the disease, it is pointed out. The vaccine works by boosting the immune system so that it effectively fights off two of the most common strains of human papilloma virus, the most prevalent STD in m...Genaera Discontinues Lomucin in Cystic Fibrosis Studies
...validate the drug's target, hCLCA1, as a potential target for future research in respiratory and other diseases and we maintain a strong intellectual property position and library of over 15,000 compounds for this target." The Phase 2 study of squalamine in prostate cancer, another of Genaera's non-core a...Single Drug to Check Both Glucose and Cholesterol in Diabetics on the Cards
...tients keep their cholesterol levels in check, and target a goal of less than 100 mg/dL for bad cholesterol levels in the blood....Violence at Croatian Gay Pride March
...Organisers said more than 20 marchers had been the target of homophobic attacks. "Around 10 people were hurt, with two needing medical treatment," Marko Jurcic, one of the organisers, told AFP. Italian senator Gianpaolo Silvestri was in one of the groups attacked, but was unhurt, Jurcic said. Police sai...Parkinsons Disease Mechanism Identified
...es in neurons and modulating a relevant downstream target rather than Cdk5 directly may be a better therapeutic strategy with regard to this pathway.......treatment target. This makes an exciting treatment target because theoretically you don't have to worry about harming nearby healthy tissue," Kridel said. Scientists used X-ray crystallography to get a three-dimensional snapshot of the drug interacting with the protein. "Understanding this drug-protein ...