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Tag: "synaptic" at medical news

Nobel Prize for Medicine shared by Three scientists

...nsduction between nerve cells, referred to as slow synaptic transmission," according to the award citation. The Nobel Assembly at Karolinska Institute said that these discoveries had been crucial for an understanding of the normal function of the brain and have resulted in the development of new drugs and an...

Food Supplements Can Prevent Alzheimer’

...ctor remaining that protected the mice against the synaptic damage and memory loss that should have resulted from their Alzheimer’s genes. Researchers say DHA is easy to add to the diet and can be found in oily fish such as salmon and sardines or can be taken in supplement form. Thus researchers suggest more...

Chemicals in clear plastics can cause learning difficulties

...such as inhibition of induction of estrogen by the synaptic connection in the hippocampus of the brain. This may lead to impaired memory as well as confusion in the sexually differentiated behavior patterns. The researchers of the study feel that the results show that long-term exposure to BPA contamination ...

Tetanus causing toxin has therapeutic properties

...oxin stops serotonin from being transported by the synaptic membranes, and thus the membranes cannot interconnect to pass on the neural signals through the brain. In comparison with the serotonin inhibitors current used, these molecules are more powerful and more effective, and work more specifically. This pr...

Learning process to be regulated by altering brain protein

...iding neurons in the embryonic brain to regulating synaptic signaling, occurs around the time of birth. A small string of amino acids gets added near one end of Apoer2 and is essential for this new function. This longer form of Apoer2 is necessary for reelin to act upon the NMDA receptor. When reelin binds to...

Tiagabine Enhances Sleep Maintenance In Insomnia Patients

...the central nervous system and tiagabine increases synaptic availability of GABA, hypnotic properties would seem a likely dose-related effect. The researchers evaluated the effect of tiagabine administered before bedtime at doses from 4 to 16 mg on sleep and next-morning alertness and psychomotor performanc...

Mice With Human Thought Processes Could Be Developed In The Future

...ls commonly found in the human brain. In addition, synaptic junctions (connection between nerve cells) were well established. Previous studies had already demonstrated that brain cells from aborted human fetuses could be injected into rodent brains. However, the functionality of these cells however remained...

Novel Protein, Staufen2 Important In Maintenance Of Nerve Synapses

...ed some of the molecular mysteries associated with synaptic connections between the neurons, that represent th...curs through these specialized contact sites. This synaptic connection is of great importance in the process of learning and remembering what has been learnt. T...

microRNA And Its Role In Synaptic Regulation

...environment. It helps in the strengthening the new synaptic junctions and breaking the old unnecessary ones. ...s that the microRNA are responsible in controlling synaptic development. A single neuron can give rise to thousands of synapses. He says that it is very importa...

Antidepressant drugs interacts with Immune cells

...feeling and eases depression by moving through the synaptic spaces of neurons. Researchers have found that these anti-depressant in the same way they work with brain cells also interacts with immune cells by a physical contact by activating the dendrite cells to increase its memory against a particular antige...

Neurotoxins might Reverse Mononeuronal Disease – Study Find

...ause they are fantastic molecular tools to dissect synaptic mechanisms,’ Dr Meunier said. ‘The aim of our lab is to understand the molecular mechanism underlying neuronal communication. The legacy of millions of years of evolution and competition between venomous species has resulted in deadly neurotoxins c...

Study Shows Tomosyn Plays an Important Role in Learning and Memory

...‘So understanding how proteins function to control synaptic strength is really important.’ Richmond and her co...ecording technique she developed to understand how synaptic proteins affect release of neurotransmitters at the nerve cell junctions. The lab's ability to study...

First Study to Show How Immune Cells 'Speak' to Each Other in Vivo

... further experimental exploration of immunological synaptic function during normal and pathological immune responses in vivo. The mechanism of how immunological synapses 'speak' to each other in vivo has not been observed prior to this research. Although formal proof of this awaits the development of drugs ...

Research Reveal A New Angle On Neural Circuits.

...hibition. Specifically, the strength of inhibitory synaptic connections between two types of neurons in the layer receiving the input – the inhibitory fast-spiking basket cells and the excitatory star pyramidal neurons – increased 3-fold. While it has been historically believed that regulation of excitatory...

Fruit fly’s visual map based entirely on genetic inputs

... only a few thousand genes can program billions of synaptic connections." Source-Eurekalert GYT...

Zinc – A New Key Player In Brain Circuitr

...ed in our paper disclose a pivotal role of ambient synaptic [zinc ion] for glycinergic neurotransmission in th...luded that their results implied that manipulating synaptic zinc levels could affect the neuronal action of zinc, but that such manipulation "highlights the com...

Blame Myelin for Many Neuropsychiatric Disorders

..., using drugs that are known to improve a neuron’s synaptic signaling in people who suffer diseases like Alzheimer’s. Furthermore, he notes, some clinical and epidemiological data suggest that such treatments may modify or even delay these diseases. Looking at such effects from a myelin-centric point of vi...

Protein ‘Fingerprint’ in Spinal Fluid Could Spot Alzheimer’s Disese

.... Still other proteins in the panel were linked to synaptic dysfunction – the breakdown of communication between brain cells that occurs as Alzheimer’s disease progresses. “A subsequent validation group of 10 patients with suspected Alzheimer’s and 18 healthy and demented control subjects turned up similar ...

Estrogen Curbs Appetite: Research

...vath and his team found that that estrogen induces synaptic plasticity in the hypothalamus, so they looked to see whether those alterations by estrogen were in line with the proposed shift in the activity of the hypothalamus. In future studies, Horvath and his team will analyze brain-specific mimics of estr...

Estrogen Curbs Appetite In Same Way as the Hormone Leptin

...vath and his team found that that estrogen induces synaptic plasticity in the hypothalamus, so they looked to see whether those alterations by estrogen were in line with the proposed shift in the activity of the hypothalamus. In future studies, Horvath and his team will analyze brain-specific mimics of estr...

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