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Tag: "switch" at medical news

Triptolide: A Potential Drug for Polycystic Kidney Disease

...ypes. Normal kidney tubule cells have a built in switch for regulating their growth — two proteins, PKD1 and PKD2, located on a bristle-like cilium that bends in response to fluid flow across the cell. During kidney development, cells destined to line a kidney tubule grow and divide until the tubule is fo...

Doctors Hopeful for Elizabeth Edwards

...me resistant to one treatment over time, forcing a switch to something else. But experts say this can extend the life of even a late-stage cancer patient for years. "There is hope,” Burstein says. "A recurrence of cancer does not mean there's no hope, and people can live a very productive, comfortable lif...

Improved Platelet Life Span Increases Better Patient Care

... We now know the identity of the precise molecular switch responsible. The team is now actively pursuing a d...rug development program aimed at manipulating this switch in order to prolong the life span of blood bank platelets, increasing their availability to patients...

New Ribosome Finding Could Lead to Antiviral Therapies

...ocated in a ribosomal protein called L3, acts as a switch to help the ribosome coordinate all of its functio...inate ribosome-associated functions by acting as a switch or a gatekeeper,” Dinman said. “When you alter the L3 switch, you alter the way the ribosome coordin...

Antidepressant Medication Has No Effect on Bipolar Patients

...but they are thought to confer a serious risk of a switch from a depressive episode to a manic episode. Fi...g that the antidepressants did not trigger a manic switch any more than placebo. Finally, when comparing the two antidepressants to each other, both showed si...

Constipation Drug Linked to Heart Attack Pulled Out

...scribe Zelnorm should work with their patients and switch over to more appropriate treatment, the FDA has said. GP...

Switching Genes to Overdrive Improves Muscular Dystrophy Symptoms in Mice

...demonstrated that manipulating a genetic molecular switch increased the genes’ activity in the muscles of mice with Duchenne muscular dystrophy, slowing the disease-associated muscle wasting. The authors caution that they have not yet found a way to tweak the switch, known as PGC-1alpha, in humans. “I thi...

Baby's First Toothbrush Should Be a Cotton Swab

...irst teeth. //Once a child has four or five teeth, switch to a baby toothbrush. Parents can start teaching their children about toothbrush use at age three. Most children of that age only manage to clean the surface of the teeth, meaning parents have to help out with the rest. Once children reach school...

US Confronted by a Major Healthcare Crisis, Say Critics

...l Health Program, which wants the United States to switch to a government-run healthcare system, as in Canada. "Our healthcare is in a car that is accelerating toward a cliff," Alan Sager, co-director of the Health Reform Project at Boston University, remarks caustically. The government does provide sub...

Is There Any Clinical Benefit to Staying on a Failing Regimen?

... further drug resistance mutations if they did not switch treatment. They carried out a retrospective study using stored plasma samples from participants in the EuroSIDA cohort. Selected for study were patients who had been on a virologically failing regimen for at least six months, and thereafter, had tw...

Costlier Health Care Weigh Downs the Women

...d for a national debate where the employers should switch to policies with higher deductibles and more bendable and low cost alternatives should be adopted for the 44 million uninsured and 16 million underinsured people in the country. It has been found that women have higher health needs but lower income...

A New Pill to Burn Away Unwanted Fat

...S scientists claim to have devised a drug that can switch on a gene to burn body fat, offering hope of an ex...g mimics normal fat and chemically triggers a gene switch called PPAR-delta. Turning on this switch activates the same fat-burning process that occurs during ...

Chinese Medicinal Compound Stops Formation of Cysts in Polycystic Kidney

...eive a signal that the tubule is fully formed. The switch that turns on that signal consists of the growth r...ood copy of PKD1 is lost in some cells, which then switch to the hyperproliferative state. As the person's kidney begins to develop these cysts, the kidney be...

Recent Research Holds Wealth of Promise to Bone Marrow Patients

...nt is that if you can start much earlier you could switch it off with less use of drugs, with fewer problems and stop the fire gaining hold." Prof Hart explained the present treatment which involved giving drugs after the onset of infection; but it would greatly help if it is treated before the onset, so ...

Women Risk Their Lives by Driving in High Heels

...ge while driving. However, only 23 pct wanted to switch to shoes while driving, though they knew it was safer. Almost 65 per cent said that they need better guidelines for appropriate footwear. Dianne Ferreira, of the road safety charity Brake, said: that high heels and flip-flops can really weigh down ...

New Therapeutic Approach for Autoimmune and Inflammatory Diseases

... that retinoic acid plays a role in modulating the switch between these two distinct (T cell) lineages the induced regulatory T cells, which are anti-inflammatory, and the TH-17 lineage, which promotes inflammatory responses, said Casey Weaver, M.D., a University of Alabama, Birmingham, professor and prom...

Drugs may Help Turn on Gene Switched Off in Cancer

... While the existing HDAC inhibitors were found to switch on the BRM gene, the effect was short-lived and reduced as the drugs were taken away. The HDAC inhibitors are not the perfect answer, but in principle this tells us we can turn our gene back on. If we can turn the gene back on, it may not be a cure f...

Stem Cell Transplants Ease Parkinson's Symptoms in Monkeys

...gest they may do more than that. They may actually switch on the brain's own innate repair mechanisms," says neuroscientist John Sinden from the UK stem-cell company ReNeuron. Evan Snyder from the California based Burnham Institute for Medical Research says that much more basic research needs to be conduc...

Dogs Reasoning on Par With Human Toddlers: Study

...ncluded that their mothers had used their heads to switch on the light because their hands were occupied. University of Vienna researcher Friederike Range said that this showed that dogs imitate selectively. 'The fact that the dogs imitate selectively depending on the situation has not been shown before...

AIDS Incidence in India Far Lower Than Previously Estimated New Study

...backs of many trucks, Use Dipper at Night, meaning switch to low-beam lights. Anjali Gopalan, executive director of the Naz Foundation (India) Trust, which runs an orphanage and fights stigmatization of AIDS victims, said she was skeptical of any estimate as low as two million. But whatever the figure turne...

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