Just One Cigarette can Cause Nicotine Addiction
...me smokers, novice smokers find that one cigarette suppresses withdrawal for weeks at a time," explained Dr. DiFranza. "One dose of nicotine affects brain function long after the nicotine is gone from the body. The important lesson here is that youth have all the same symptoms of nicotine addiction as adults...Aspirin may Help to Prevent Colon Cancer in High-risk Individuals
...found that a new Celebrex-like gene called 15-PGDH suppresses the grown of colon cancer, which may lead to the development of a new drug for colon cancer prevention. Celebrex is a naturally occurring Cox-2 inhibitor. The findings of the study were published in May issue of New England Journal of Medicine....Beware, America's Fast Food Consumers!
...s there's evidence that suggests fructose actually suppresses your fullness, unlike fiber-rich foods, which make you feel full quickly. The take-home message for humans is obvious, he says. "A high-fat and sugar-sweetened diet compounded by a sedentary lifestyle will have severe repercussions for your liver a...MicroRNAs Can Be Tumor Suppressors
...nds to the 3' end of the HMGA2 mRNA transcript and suppresses its expression in the cell cytosol. However, chromosomal breaks that shorten the 3' end of the HMGA2 transcript,and prevent let-7 binding, result in aberrantly high levels of HMGA2 expression and tumorigenesis (formation of tumors). This paper esta...Indian American's Contribution in Cancer Gene Discovery
...major breakthrough in the discovery of a gene that suppresses the growth of cancer// tumors in humans. Anindya Bagchi, along with a group of scientists at the Cold Spring Harbor Laboratory (CSHL), a private research institute in Long Island, New York, have successfully identified a gene, which if faulty allow...Chilli Extract may Stop Fat Cell Growth
...ese results demonstrate that capsaicin efficiently suppresses adipogenesis in 3T3-L1 pre-adipocytes and adipocytes," concluded the researchers. Capsaicin has been used in folk medicine as a remedy for rheumatism. The humble red chilli pepper has also been in the news recently with research linking the spice t...Higher Physical Activity Level Slows Lung Function Decline in Smokers
...is decline in new cases to regular exercise, which suppresses the production of inflammatory markers in the lungs caused by smoking, and reduces the pathogenesis of COPD. Until now, smokers’ only options for slowing lung function decline included stopping smoking and reducing occupational exposure to smoke. ...Computer Tool Helps Pinpoint Risky Gene Mutations
...possibly because they disable a gene that normally suppresses cancer. To test the computer tool, Karchin and her colleagues used it to analyze 36 “point mutants” on the BRCA1 gene, meaning locations where a single letter in a string of DNA differed from the sequence found in the general population. This mutat...Scientists Uncover Cause of Antipsychotic Drug Weight Gain
...earchers then gave the mice leptin, a hormone that suppresses appetite, and as suspected, saw lowered AMPK levels. Drilling down further into what controls AMPK and its boost of hunger, Sangwon Kim, Ph.D., a research associate and lead author of the study, “rounded up the usual suspects, brain proteins known...Don’t Kill Your Skin With Bleachers, Warns Doctor
...ful effects of the sun, hence using any cream that suppresses melanin production, can only have adverse effects, according to doctors. The government has banned creams by the names Neprosone Gel, Hyprogel, Dermo Gel Plus and Movate Cream among others.In addition to the heavy campaigning against bleaching, fin......emical- a hormone pancreatic polypeptide (PP) that suppresses hunger pangs once the stomach is full. Some people have pancreatic tumors and in this case more than required amounts of PP is produced, rendering the person chronically thin. Says Bloom, "Developing a treatment based on natural appetite suppress...Dual Gene Therapy Suppresses Lung Cancer in Preclinical Test
...ination achieved greater cell suicide because FUS1 suppresses a gene that expresses a protein known to rapidly degrade p53, says senior author Lin Ji, Ph.D., M. D. Anderson associate professor of thoracic and cardiovascular surgery. The FUS1/p53 combination also activates a cell suicide pathway based in the ...Intestinal Bacteria May Cause Obesity
...cteria affects production of this enzyme, and also suppresses the body's fasting-induced adipose// factor, causing excess accrual of fat resulting in obesity. It is hoped that the new discovery will motivate researchers to find methods of counteracting the bacteria. PRI...Estrogen Curbs Appetite In Same Way as the Hormone Leptin
...ssue of Nature Medicine. “We found that estrogen suppresses appetite using the same pathways in the brain as the adipose hormone leptin,” said lead author Tamas L. Horvath, chair and professor of Comparative Medicine and professor in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale Sch...Estrogen Curbs Appetite: Research
...sue of Nature Medicine. "We found that estrogen suppresses appetite using the same pathways in the brain as the adipose hormone leptin," said lead author Tamas L. Horvath, chair and professor of Comparative Medicine and professor in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale Sch......iving her body estrogen and progesterone, and that suppresses her own hormonal fluctuations,” Ernst says. “So she’s already controlling her cycle by taking those hormonal contraceptives and can further control her cycle by eliminating the pill-free interval or placebo pills.” She notes that the practice of ph...Estrogen Study Provides New Hope For Colon Cancer Treatment
...rs offer three possibilities: the hormone directly suppresses the cells' growth; it decreases the production of bile acids which are known to spur cancer; or it blocks certain genetic changes within colon cells that lead to cancer."Further efforts are needed to bring these mechanisms to light," comments Chan, w...Soy’s Restorative Powers Confirme
...s in multiple sclerosis, but they theorize that it suppresses the immune response to some extent, in addition to inhibiting proteases. Dr. Rostami sees BBIC as being used as a single therapy or in conjunction with other drugs in treating MS. He notes that because current therapies for MS involve injecting drugs...New data from NIH lab confirms protocol to reverse type 1 diabetes in mice
... with Freund's complete adjuvant, a substance that suppresses the activity of the immune cells that destroy islets in type 1 diabetes. They also introduced donor spleen cells to retrain the immune system not to attack islets and found that the protocol not only halted the immune destruction caused by diabetes b...... at all clear how the cell allows one response and suppresses the other. That likely is because the G proteins activated by epinephrine receptors don’t readily dissociate, contrary to the textbook picture. MCG researchers have also shown that at least one other class of G proteins does dissociate, suggesting ...