Tag: "substrate" at medical news
Nobel laureates in chemistry
...lyst that could transfer chirality to a non-chiral substrate
and get a chiral product. This development has been led by another of this year's Laureates in chemistry, Ryoji Noyori. The Japanese scientist Ryoji Noyori has carried out extensive research and developed better general catalysts for hydrogenation....
Tamiflu substrate produced from Bioengineered Bacteria
...hich will be used by the bioengineered E.coli as a substrate
for production of high quality Shikimic acid....
No Increased Schizophrenia Risk With Use Of Cannabis
...alty associated with personal possession of such a substrate
would be much lower. This decision has led to mixed reaction from health officials who are worried that cannabis could be perceived as a relatively safe drug. The council members have however warned that the possibility of cancer and bronchitis ass...
Ibuprofen and Vitamins C and E Could Halt Alzheimer's
...ount of amyloid in the brain (with ibuprofen), the substrate
that causes inflammation." APOE-4 carriers seemed to have the biggest benefit from the combination of all three drugs. And these patients, all in their 60s or 70s did not show any decline in their mental faculties in the 8-year follow-up study. "So i...
Experiments In Outer Space To Determine single Cell Survival
...ers to deposition of the cell slurry on a spinning substrate
until dry. From their comfortable "home," the empowered cells can also direct their own landscaping. They can organize metallic nanocrystals added at the cell surface. These may enhance the sensitivity of Raman spectroscopy for monitoring the onset...
Researcher Hits Bulls-Eye for Antibiotic Target
...protein chews away until it reaches the end of the substrate
chain." Sanders worked with a team to create the first-of-its-kind animated movie showing this process from the point of view of the substrate. The audience follows along as it is pulled through the protein from one side to the next. "This is the...
Drugs Delivery Revolutionized by Extremely Stable Glass
...ails depositing vapors of organic molecules onto a substrate
cooled to 50 degrees (Celsius) below the glass transition temperature—the point at which a compound normally begins to solidify en route to becoming glass, a frozen, liquid-like structure with no long-range internal order. Conceived by UW-Madison che...
Experimental Flu Vaccine Appears Promising in Early Tests
...recognized disadvantages to the use of eggs as the substrate
[the base on which an organism lives or grows] for influenza vaccine. Eggs require specialized manufacturing facilities and could be difficult to scale up rapidly in response to an emerging need such as a pandemic," the authors write. They add that d...
Cytokine Resistance Contributes to Pathology of Type 2 Diabetes
...ut the second pathway, called the insulin receptor substrate
2 / phosphatidylinositol-3 kinase (IRS-2/PI3K), which was more of a mystery. One of the actions of diabetes is to create intracellular insulin resistance. Some of the cytokines that work on cells share the same pathways as the insulin receptor, Fre...
Researchers Develop Material That Self Heals Like Human Skin
... which liquefied was extracted, leaving behind a substrate
with a network of interlocking microchannels. In...twork with a liquid healing agent. The coating and substrate
were also bent until a crack formed in the coating. According to Sottos, the crack propagated thro...
New Technique Dissects Stem Cells' Picky Likes, Dislikes
...he surfaces of other cells, as well as adhere to a substrate
called the extracellular matrix (ECM). These inter...an extract from mouse cells that often serves as a substrate
for growing stem cells in culture. In a series of weeklong experiments, the team placed human emb...
"Decryption" of Enzyme's Functions Paves Way for Future Drug Discovery
... that exist only briefly as the catalyst turns the substrate
into a new molecule. "To tell the truth, we were very surprised that the docking approach worked to determine the substrate. There's so many ways that the approach can go wrong. We're all very gratified," Nature magazine quoted Shoichet as saying....
Translating Structure into Function
...a catalyst. This was a search for the so-called substrate
for the enzyme, a search that has never succeeded ... that exist only briefly as the catalyst turns the substrate
into a new molecule. Because these intermediates are unstable, scientists have until now been unab...