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Tag: "structure" at medical news

Common BP Drug Treats Muscular Dystrophy

...e activity of TGF-beta might restore normal muscle structure and function. First, the research team injected Marfan mice with a protein that binds TGF-beta and renders it inactive. This TGF-beta-blocking protein caused muscle fibers in these mice to grow bigger than those in untreated Marfan mice. "Not only...

Probing the Effect of Endurance Exercise on Athletes' Hearts

...led left ventricle, with subsequent changes to the structure of the RV." Prof Heidbüchel said that athletes who undertake endurance sports should not worry too much. Ventricular arrhythmias are very uncommon. "But they need to be vigilant and honest with themselves: if they have a family history of ARVC, ar...

Researchers Explore the Effect of Engineered Immune Cells on HIV

...ry to make copies. HIV also possesses an unusual structure and a keen ability to hide from antibodies in a sugar-coated shield. The shield has very few open spaces on its surface, Wang says, which makes it virtually impossible to puncture. But because the virus also has n uncanny ability to hide, HIV often g...

Childhood Obesity Linked to Foot Pain

...d ankle surgeon in Boston. The foot is a complex structure consisting of 26 bones, 33 joints and more than 10...g new evidence that childhood obesity changes foot structure and results in instability when walking.' Being overweight flattens the foot, straining the plantar ...

Patients Dissatisfied Following Closed Reduction Of Nasal Fractures

...any of the patients reported improvements in nasal structure and function following surgery, the large number of dissatisfied patients suggests that alternative procedures might work better for some, the authors continue. 'A stringent preoperative assessment is paramount, before patients are advised to undergo...

Vitamin A’s Link With Gullet Cance

...ors. According to this finding, the change in cell structure can be seen below the top layer of cells too. Oesophageal Adenocarcinoma is one of the common forms of oesophageal cancer and in the United Kingdom alone around 7500 people are affected by this disease every year which has a near 100% mortality...

Link Between Family Size and Stomach Cancer Found

..., providing more reliable data to assess if family structure influenced the risk of cancer. Dr. Blaser and his colleagues, who published a study in the mid 1990s in The New England Journal of Medicine on the relationship between H. pylori and stomach cancer based on this Hawaii cohort, went back to the blood s...

Selective Marker Found to Indicate Aggressive Form of Breast Cancer

...otein is thought to have a role in stabilizing the structure of adult stem cells as they regenerate and divide into daughter cells. 'Normal basal epithelial tissue produces nestin, but basal epithelial tumors produce a tremendous amount of nestin, which likely represents an abnormal expansion of the basal e...

Selective Marker Found to Indicate Aggressive Form of Breast Cancer

...otein is thought to have a role in stabilizing the structure of adult stem cells as they regenerate and divide into daughter cells. 'Normal basal epithelial tissue produces nestin, but basal epithelial tumors produce a tremendous amount of nestin, which likely represents an abnormal expansion of the basal e...

Secrets of the Heart's Signals

... Although small, rabbit hearts are very similar in structure to human hearts. "We have one of the most advanced cardiac models out there," Trayanova explains, adding that her team has already modeled the behavior of ischemic rabbit hearts and are hoping to move on to the impact of infarction. Because defibri...

Hypertension, Prehypertension in Youngsters Linked With Heart Enlargement

...sion were more likely to have changes in the heart structure associated with increased cardiovascular risk: hig...with clinical characteristics and changes in heart structure and function in 1,944 participants (57.5 percent women) of the Strong Heart Study, an ongoing study ...

Age, Gender Major Factors in Severity of Auto-Accident Injuries

...al differences relating to height, weight and body structure and vehicle design attributes that affect drivers differently. Another possibility is that vehicle safety systems, such as safety belts and airbags, may be more effective for some age and gender categories than for others." While alcohol played a ro...

Researchers Looking for Genes That Control the Brain

... of its kind to map out normal variations in brain structure and function and identify the genes responsible fo...al illness and studying differences in their brain structure and function, this research team is working with large family groups from the average population to ...

Herpes Simplex and Alzheimer’s Disease Linked to Single Gen

...mehow disturbs the receptor, possibly altering the structure and function of the synapse. Damage to synapses is one of the earliest signs of Alzheimer's disease. Another possibility is that the body's immune response against herpes somehow damages the brain, and that such damage is worse in people with the Ap...

NRI Doctor's R&D Model in India to Slash Cost of Drugs

...aceuticals". Improvements devised to the molecular structure of an existing, expensive drug turned it technically into a new medicine, which was no longer under a 20-year patent to a multinational drug company and could be made and sold cheaply. "The process has the potential to undermine the monopoly of the...

MIT Creates 3-D Scaffold for Growing Stem Cells

...lls grow and behave in the body, the new synthetic structure can provide a more conducive microenvironment for tissue cell cultures and tissues used in regenerative medicine, such as skin grafts or neurons to replace brain cells lost to injury or disease. The scaffold itself can be transplanted directly into...

Manmohan Calls for Statistical Reforms in Healthcare and Education

... number of recommendations including reform of the structure of the Indian Statistical System and upgrading its infrastructure to ensure autonomy, improvement in the collection of datas, exploration of alternative techniques for collection of datas, identification of new data series that may need to be generat...

Tuberculosis: The Bacillus Takes Refuge in Adipose Cells

...They did this by testing for traces of the genetic structure of the bacillus in samples from people considered not to be infected. Analyses were carried out on samples from deceased subjects from Mexico, where tuberculosis is endemic, and from Parisian districts reporting very few cases of tuberculosis. The ...

Structure of Iron Regulatory Protein-RNA Complex Solved

The surprising structure and properties of a protein responsible for regula...as drugs targeted to the three-dimensional protein structure emerged in the last century, "knowing how the iron response element RNA is folded in the IRP1 comple...

Genetic Mechanism Helps Explain Chronic Pain Disorders

...he COMT gene can dramatically affect the secondary structure of corresponding messenger RNA - which, in turn, l...ant differences in how they code for the secondary structure of messenger RNA, or mRNA. The differences lead to dramatic alterations in protein expression, which...

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