Inactivation of Rad9 in Tumor Cells Would Be Advantageous In Cancer Therapy
... Further research has to be conducted on how Rad9 stabilizes the telomeres. It is thought that in the absence of Rad9 certain proteins associated with the telomeric structure become delocalized thereby exposing the DNA at the ends of chromosomes. This research also would help in identifying people with mutat...Switching Off Protein Could Play Key Role In Success Of Radiation Therapy For Cancer
...them from fusion or degradation. "We saw that Rad9 stabilizes telomeres, and because we aren't yet sure how it does it, we will continue to study how Rad9 influences the telomere structure," Pandita said. "We speculate that without Rad9, some of the other proteins associated with the telomeric structure become ...Global Seagrass Decline Affects Shallow-water Ecosystems
... root and rhizome system of these flowering plants stabilizes sediments, protecting the coastline from currents and weather-related erosion. Seagrass is an effective filter of nutrients and particulates, and it is the basis of a detrital food chain that feeds fish and shellfish. When seagrass beds disappear, ......ide linkage -- a bond within an SOD1 molecule that stabilizes the structure. Intermolecular disulfide bonds, or cross-links, are incorrect bonds that form between, not within, SOD1 molecules. "A year ago we demonstrated that ALS mutations have the greatest effect on the most immature form of the SOD1 protein,...Brain Matures Emotionally with Age
...he plasticity in the medial prefrontal brain which stabilizes the negative and positive emotion. Professor Helen Fisher, an expert in human emotion at Rutgers University in New Jersey said that it has opened new dimensions in understanding of the aging process. Dr Simon Surguladze, deputy head of the department...Modified Ligament Surgery Improves Outcomes Players, Athletes
... medial collateral ligament (MCL), which links and stabilizes bones of the lower and upper arm where they meet at the elbow. Less traumatic than the classic Tommy John surgery, the modified surgery called the docking procedure, with time, is likely to become the gold standard for treating these injuries. “...