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Tag: "sirtuins" at medical news

Vitamin Extends Life in Yeast, Dartmouth Medical School Researchers Find

...east anti-aging gene product Sir2, which resembles sirtuins found in humans. The new work builds on Brenners prior discovery of the vitamin, termed NR (nicotinamide riboside), a natural product found in milk. Like the B3 vitamin, niacin, NR is a precursor to a versatile cellular factor that is vital for all l...

Vitamin Extends Life in Yeast, Dartmouth Medical School Researchers Find

...east anti-aging gene product Sir2, which resembles sirtuins found in humans. The new work builds on Brenner’s prior discovery of the vitamin, termed NR (nicotinamide riboside), a natural product found in milk. Like the B3 vitamin, niacin, NR is a precursor to a versatile cellular factor that is vital for all ...

Anti-Aging Powers of Enzyme Sirtuins

...nstitute points to another strategy for activating sirtuins to unleash their anti-aging powers. They may also ...se sirtuin molecules." Marmorstein's research on sirtuins also links to a long line of observations concerning calorie-restricted diets and longevity. "Peop...

Cell Survival Depends on Chromosome Integrity

...that removing from yeast cells two proteins called sirtuins — Hst3p and Hst4p — causes cells to become hyperse... normal state. The cells require proteins like the sirtuins Hst3p and Hst4p to act as guideposts to help identify dangerous DNA lesions. If the DNA repair machi...

Restriction of Carbohydrates to Prevent Alzheimer's Disease

...1, a member of a broad family of proteins known as sirtuins which influence a variety of functions including metabolism and aging. Dr. Pasinetti and colleagues used an experimental mouse model to demonstrate that beta-amyloid peptides in the brain can be reduced by subjecting the mice to dietary caloric rest...

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