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Tag: "selectively" at medical news

Nanotech Wipes for biohazard detection

...you do that, antibodies in the fabric are going to selectively latch onto whatever pathogen that they match. Using this method we should, in theory, be able to quickly activate the fabric to detect whatever is the hazard of the week, whether it is bird flu, mad cow disease or anthrax.’ Frey and her colleagues ...

Immune Response Linked to “Ghost” Parasites and Severely Congested Sinuss

...s to block its production and action. “If we can selectively shut down the antiparasite immune response, we could potentially have new treatments for these airway diseases of the lung and nose,” says Lane. New therapies are needed, he says, as an alternative to long-term steroids, which block the inflammator...

Cancer-Killing Compound From A Fungus

...eously discovered a compound in certain fungi that selectively destroyed cells depending upon a gene called ras--one of the first known cancer-causing genes. They had found rasfonin, a compound that seemed tailor-made to knock out ras-dependent cancers like pancreatic cancer. After six years, however, rasfonin...

First Study to Show How Immune Cells 'Speak' to Each Other in Vivo

...e development of drugs or mutations that interfere selectively with synapse formation, the confirmation of these cellular structures increases the understanding of the immune system and paves the way for further research on the body's immune response system. New knowledge in this area may ultimately improve trea...

Chronic pain can be cooled off !

...cientists remarked: 'We have found that if you can selectively activate the TRPM8 receptor, then you have a chance of suppressing other sensory inputs coming into the nervous system that are carrying pain information. We found a very specific mechanism which means that this careful chemical-induced cooling can g...

Nicotine - New Role in Prevention of Parkinson’s Diseas

...ated experimental animals with MPTP, an agent that selectively destroys the dopamine-producing brain cells. Half of the animals also received a low-dose administration of nicotine over a six-month period. During this time, the nicotine dose was gradually increased to a level typically found in cigarette smoke. ...

Gene That Causes Atrial Fibrillation Identified

... The job of these tubes -- or channels -- is to selectively allow certain charged particles in and out of the cell, and in this way, pass electrical currents in and out of the cell to regulate each heartbeat. The KCNA5 mutation causes loss of function of an atrial-specific potassium ion channel, disrupting el...

New Way to Open Cellular Ion Channels, Implications for Drug Design

..., the channels underlie electrical signaling. They selectively allow the passage of small ions such as sodium, potassium, or calcium into and out of the cell. The precisely controlled passage of ions generates the electrical currents that enable nerve impulse transmission, hormone secretion, and muscle contracti...

Scientists Isolate Leukemia Stem Cells in Mouse Model

...g that may be good news for developing a drug that selectively targets them. Cancer stem cells are self-renewin...d if the cancer stem cells could be identified and selectively targeted with designer drugs. To test this hypothesis, the researchers sought to transform a norma...

'Awake cardiac surgery' performed at Madurai hospital

...n was completely arrested in the operation site by selectively blocking nerves using a strategically placed catheter in the back and continuously injecting drugs. This is called cervical epidural anaesthesia. One of the main advantages of the procedure is the absence of an irritating tube in the throat (used fo...

Cell Survival Depends on Chromosome Integrity

... computer science and engineering with the goal of selectively using high-throughput techniques to accelerate hypothesis-driven research and to speed development of new hypotheses. The Technology Centers for Networks and Pathways of Lysine Modification at Hopkins dissects signaling networks and pathways by dev...

How Does Leptin Work?

...stance. But in addition, our findings suggest that selectively turning on STAT3 may help prevent diabetes by improving glucose metabolism and help restore fertility as ell.’...

Autoimmune disorders studied in detail by U-M researchers.

...aneously allowing for initiation of a process that selectively kills or disables disease-causing cells.' Glick and collaborators published their findings in the June 16 issue of ACS Chemical Biology. The drug, discovered by Glick and coworkers and called benzodiazepine-423 (Bz-423), is a chemical cousin of an...

Sanitizer For Contaminated Sprouts Developed

... And what we mean by a magic bullet is that it can selectively kill the bacteria but leave the seed alone." Warriner told CTV News. Adding an oxycholoro-based sanitizer, called Germin-8-or, to the water decontaminates sprout seeds as they germinate, claim the researchers, in their work published in the Journal...

Neurotoxins might Reverse Mononeuronal Disease – Study Find

...are incurable. Dr Meunier is developing botox to selectively deliver drugs to motoneurons to directly treat motorneuron diseases. ‘I first became interested in investigating neurotoxins because they are fantastic molecular tools to dissect synaptic mechanisms,’ Dr Meunier said. ‘The aim of our lab is to un...

Site of Sleep Regulation Identified in Fruit Flies

... PKA acts to regulate sleep." Sehgal was able to selectively turn on PKA activity in a variety of brain locations, which promoted PKA expression in designated regions. Of the different regions targeted, only two regions, both present in the adult mushroom bodies, led to changes in sleeping patterns of fruit fl...

Transport of Proteins Unravels the Mystery behind Neurodegenerative Diseases

...IC. ‘A breakdown in fast axonal transport would selectively kill neurons because neurons are especially dependent on the transport system,’ Brady said. Kennedy disease is also known as spinal and bulbar muscular atrophy, or SBMA. Like the better-known ALS and Huntington's, it is a rare but devastating disease...

New Research May Be Useful for Developing Drugs for HIV and Cancer

...ers to develop new drugs to fight HIV or cancer by selectively targeting proteins known as zinc fingers. In the May 30 issue of the journal Chemistry & Biology, researchers reported that a zinc finger protein, known as HIV NCp7, can be inhibited when it is exposed to a platinum complex. They observed that when...

Elements In Grape fruit Juice Combine Lethally with Certain Drugs, leading to potentially dangerous side effects, study.

... scientists at the Florida Department of Citrus to selectively remove only the furanocoumarins from the juice. He and his collaborators then studied the effect of the whole juice versus furanocoumarin-free juice on the ability to affect absorption of felodipine, an anti-hypertension drug known to interact with...

B-Cell Biologic Therapy Could Revolutionize Rheumatoid Arthritis Treatment

...et: the B cell. Rituximab, a biologic agent that selectively depletes B cells, has been successfully used to treat non-Hodgkin's lymphoma. It has also been shown to improve disease symptoms for RA patients, when injected at aggressive levels for a two-week period. To investigate this biologic's potential long-...

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