Stressed Mice may Hold Clue to How Fat is Stored: Study
... this pathway, they said they were in fact able to selectively add fat to their test subjects. "We couldn't bel... meanwhile pointed out that the ability to add fat selectively would be useful for cosmetic restructuring, like facial reconstruction, breast, buttock and lip enha...Blocking the Y2 Receptors can Prevent Obesity
...n which we have either blocked the Y2 receptor, or selectively removed the gene from the abdominal fat cells, we have shown that stressed mice on high calorie diets do not become obese. Even more surprisingly, in addition to having flatter bellies, adverse metabolic changes linked to stress and diet, which inc...Sleep Deprivation can Affect Competent Decision-making
... involved with the anticipation of reward, becomes selectively more active when high risk-high payoff choices were made under conditions of sleep deprivation. Further, the number of high risk decisions did not increase with sleep deprivation, but the expectation of being rewarded for making the high risk gamble ...Suicide Gene Therapy Kills Bowel Cancer Cells
...Because this drug is only activated in tumours, it selectively kills only cancer cells. In normal tissue, the dru...peutics, said: We have developed a smart method to selectively target cancer cells. Normal cells are spared because the virus doesnt produce the protein that activ...Scientists Activate New Cancer Drug Using Light and Oxygen
...d Wilson have demonstrated that tumor cells can be selectively attacked using a PDT. When the light activates this new drug, it then works to produce a reactive form of oxygen, which destroys only the cells that have been marked by the cancer-fighting drug, thereby sparing other normal healthy neighboring cells....Nanocomposite Labeled Cancer Cells Targeted and Destroyed by Using Lasers
... labeling cells with CNDs, light absorption can be selectively and locally enhanced wherever composite nanodevices are present. Irradiation of the mix of labeled and unlabeled cells by laser light, causes tiny bubbles to form that disrupt and damage the labeled cells, but leave unlabeled cells unaffected. This t...Experts to Develop New Weapons Against Food Poisoning
...cteria with a high degree of efficiency, and do so selectively and specifically, without affecting beneficial bacteria or gut cells. The term is commonly used in its shortened form, phage. Both GangaGen and The University of Nottingham are leaders in bacteriophage research and view the technology as a vital br...FASgen Announces New Diagnostic Research Test for Steatohepatitis
...y has designed and synthesized many compounds that selectively inhibit fatty acid biosynthesis. One group of these compounds holds great promise for new a highly specific therapeutics for cancer; additional compounds have the potential of specific therapeutics for obesity and related metabolic disorders. For mor..."Pre-treatment Blood Test" A New Guide to Lung Cancer Therapy
...es affect proteins and signaling pathways that are selectively activated in certain malignant cells and not in normal cells. But this selectivity makes these therapies effective only for the subset of patients whose tumors are driven by the targeted pathways. The drawbacks of treating every patient with a targ...Dogs Reasoning on Par With Human Toddlers: Study
...ate selectively. 'The fact that the dogs imitate selectively depending on the situation has not been shown before. We were very surprised to see this 'selective imitation' by the dogs. They didn't just copy blindly what they saw,' the Daily Mail quoted him, as saying. Fellow researcher Zsofia Viranyi, of Eot...Scientists Spotted Out Tumor Vessel by Molecular Markers
...sites. The study also revealed 13 genes that are selectively overexpressed in tumor blood vessels. Although the function of most of the newly identified genes in tumor blood vessels is unclear, many of the genes encode cell surface proteins, making them appealing targets for the development of new therapeutic ...Photodynamic Therapy can Scramble the Immune System to Fight Cancer Spread
... tumour after one of these drugs has been injected selectively activates the drug in that area, treating the cancer but avoiding some of the side effects associated with chemotherapy. Researchers from the Roswell Park Cancer Institute in the US have now shown that one particular form of PDT might have the pote...Newspaper Analysis positive Results for Organ Transplantation
.... One theory of media influence holds that media selectively influence opinion leaders on an issue, who in turn discuss the topic with individuals who may not attend to the issue in media," Feeley noted. "I think this is what happens with organ donation." To get a fuller picture of the role of the media, fut...Sleep Deprivation can Affect Competent Decision-making
... involved with the anticipation of reward, becomes selectively more active when high risk-high payoff choices were made under conditions of sleep deprivation. Further, the number of high risk decisions did not increase with sleep deprivation, but the expectation of being rewarded for making the high risk gamble ...Arcoxia Slammed –Nothing Better Than Vioxx Says FD
...ewly developed drugs for treatment of inflammation selectively block an enzyme called COX-2. Blocking this enzyme blocks the production of the chemical messengers (prostaglandins) that cause the pain and swelling resulting from arthritis inflammation. Though they are supposed to be gentler on the stomach, ma...Scientists Identify Critical Gene Factor in Heart Development
...uring out what a particular gene does in a cell by selectively removing it. "Development of the heart requires very careful regulation of many factors, and that's one reason that microRNAs are so exciting to us," said Dr. Srivastava, GICD Director. "By knocking out the gene for one miRNA, we could determine e...Stem Cells Provide New Tool for Studying Disease and Identifying ALS Drugs
...del of ALS, a fatal neurodegenerative disease that selectively destroys motor neurons, messenger cells responsible for virtually all voluntary movement. Until now, scientists have not known whether motor neurons in ALS die because of a problem within the cell—or from outside the cell. The study by Eggan's grou...Merck's Pain Reliever Arcoxia Rejected by US Federal Advisory Panel
...ewly developed drugs for treatment of inflammation selectively block an enzyme called COX-2. Blocking this enzyme impedes the production of the chemical messengers (prostaglandins) that cause the pain and swelling resulting from arthritis inflammation. And they are supposed to be gentler on the stomach, makin...A Sweet Step Toward New Cancer Therapies
...they first showed that their method can be used to selectively cleave different bonds and then demonstrated that it can be used to identify sulfate-laden proteins and to pinpoint the location of the sulfate groups on them. In the latest research, they extended the technique to sugars, an even more challenging ...Genetic Pathways to Curable and Incurable Forms of Pancreatic Cancer Identified
...he pancreatic cancer oncogene called Kras and then selectively mutating tumor-suppressor genes such as p53, p16 and Dpc4 in different combinations. In the mouse model, which Hingorani first developed while at the University of Pennsylvania, the combination of Kras and p53 led to the more deadly form of pancre...