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Tag: "selective" at medical news

Obesity Linked to Lower Tuberculosis Risk in Older Chinese Population

... authors said. The presence of such a strong but selective association across the whole spectrum of BMI could have major biological, clinical and/or epidemiological implications. Further studies are indicated to explore the underlying mechanisms, potential clinical utilities and possible epidemiological cons...

Common Antidepressants Linked to Increased Bone Loss in Older Adults

... women . The antidepressant medications known as selective serotonin reuptake inhibitors (SSRIs) treat depression by inhibiting the protein that transports serotonin, a neurotransmitter involved in sleep and depression, according to background information in the articles, and which has recently been discover...

The Bottleneck in Neuroblastoma

...approaches are targeted therapies--aimed in highly selective ways at cancer cells, but sparing healthy cells, said Maris. But in order to best guide us to the most appropriate treatments, we need greater understanding of the abnormal biological events that give rise to neuroblastoma. One crucial technique fo...

FDA Approves INTUNIV (guanfacine) for the Treatment of ADHD

...(previously referred to as SPD503), a nonstimulant selective alpha-2A-receptor agonist, which has been studied ...ility, impulsivity, and frustration tolerance. The selective alpha-2A agonist strengthens working memory and prefrontal cortex neuronal firing. This research sup...

Genetic Tests Could Help Decide the Right Anti-depressants

...xample, some depressed patients respond quickly to selective serotonin reuptake inhibitors (SSRIs), which relieve depression, in part, by flooding the brain with serotonin. Serotonin is a hormone that transmits nerve signals between nerve cells and also causes blood vessels to narrow. Changes in the serotonin ...

Orissa CM Orders Probe into Female Foeticides

... banned the practice of prenatal sex selection and selective abortion more than a decade ago. However, it remains a common practice in Orissa and in several parts of the country that claims about half a million female lives each year, Mohanty said....

New Study Challenges NICE Guidelines on Adolescent Depression

...d that adding cognitive behaviour therapy (CBT) to selective serotonin reuptake inhibitor (SSRI) treatment is unlikely to improve outcomes for adolescents with moderate to severe depression. These findings challenge current NICE guidelines that recommend SSRIs be prescribed only in conjunction with psycholog...

Kerala Institute to Hold International Seminar on Drug Discovery

...screening of ligands and focused library design of selective estrogen receptor. Modulators using combinatorial docking method, quantum mechanics in structure based drug design, novel methods to predict protein conformational changes during ligand binding are included for deliberations. Jorg Weiser, vice pr...

Alien Hand Syndrome Causes Random Hand Movement

...new finding is that AHM was associated with highly selective and isolated activation of the contralateral primary motor cortex. The fact that motor cortex activity was identical during AHM and voluntary movements indicates that conscious and unconscious motor activity involves the same underlying brain struc...

Key Mechanism to Emergence of Strep Bacteria

...ear a simple strep infection, they apply a natural selective pressure favoring the genetic mutation. The mutation allows the bacteria not only to survive neutrophil killing, but to spread and destroy tissues, as is seen in necrotizing fasciitis and other severe forms of strep infection, said Walker. The re...

India to Monitor Pregnancies to Check Girl Foeticide: Report

...tory registry of pregnancies and abortions to stem selective abortions of girl fetuses, a minister said, accor...orldwide average of 1,050 females -- mainly due to selective abortion in the country where many people prefer to have male children. "This will check both foet...

Natural Selection in Butterflies

...ws that when a population experiences very intense selective pressures, such as an extremely skewed sex ratio, evolution can happen very fast." Charlat pointed out that, unlike mutations that govern such traits as wing color or antennae length, a genetic change that affects the sex ratio of a population has ...

Protein Interaction is a Drug Target for Blood Clot Prevention

...critical for integrin activation in mice, and that selective disruption of the talinalpha-IIb beta 3 interaction protects mice from pulmonary thromboembolism the formation of blood clots in the vessel that carries blood from the heart to the lungs. Furthermore, this blockade results in very little pathologic...

Cell Toxin Inhibits Survival Protein in Cancer Cells

...version of antimycin called 2-Methoxy antimycin is selective in killing cells that have high levels of Bcl-2 and Bcl-xL proteins. The over expression of these proteins in many types of cancer cells correlates with resistance to chemotherapy and radiation therapy. Cells with normal levels of Bcl-2 or Bcl-xL a...

Insulin Sensitizer- Energy Conserving Signal to Brain

...e over the central nervous system and suggest that selective inhibition of the chemical in the brain may represent a novel therapeutic strategy for obesity and obesity-linked diseases, he added. White adipose tissue (WAT) is a major site of energy storage and plays an important role in energy balance, the re...

Alternative Option for Type2 Diabetes Treatment

...d the first oral incretin enhancer, sitagliptin, a selective DPP4 inhibitor (a class of oral hypoglycemics), for use as monotherapy or in combination with other medications. The effectiveness of this class of medications in managing type 2 diabetes is not well understood. Renee E. Amori, M.D., of Tufts-New E...

WBC Selective About Sugar

Neutrophil is selective of its reaction to a particular variety of sugar present on the surface of pathogenic fungi . According to Biology textbooks neutrophils are regarded as mindless killers. White blood cells (WBC) form an integral part of blood. They are the policeman...

Completely Neutral Evolutionary Changes Helped Shape Our Genome

...etic changes that manage to stick around have some selective advantage. But our work adds to the case that frequently, we are what we are largely due to random changes that are completely neutral," said Nicholas Katsanis, Ph.D., Associate Professor at Hopkins' Institute of Genetic Medicine "I am not at all d...

Reduction in Antidepressant Leads to Suicidal Risks

...y agency] declared the risk-benefit profile of all selective serotonin reuptake inhibitor (SSRI) antidepressant...ressant linked to suicidal thoughts and behaviors, selective norepinephrine reuptake inhibitors. New users of fluoxetine, the only antidepressant approved by t...

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