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Tag: "scaffolding" at medical news

Secret Of Heartbeat Protein Unravelled

...and also plays a role in drug addiction. A similar scaffolding mechanism is at work in the heart, where it affects basic functions, including the heartbeat. SAP97 is a complex protein made up of five "domains" similar to a train comprising an engine and four boxcars. In their experiments, Mierke and other resea...

Scientists use plastic to help body make new bone!!!!

...e where the fracture once was. This bone scaffolding is inbuilt with proteins called growth factors, which are released into the body once the plastic disintegrates inside the body. These proteins also help in increasing the blood supply to the affected site and thus the fracture heals faster. The fast...

Chronic Pain Syndrome May Be In The Genes

...s form protein filaments that provide the internal scaffolding of cells, and play key roles in the process by which cells divide. Out-of-control septins are implicated in certain abnormal cell divisions that lead to tumor formation, including breast cancer. Cells depleted of SEPT9 often fail to complete normal c...

Schizophrenia Complicates With Altered Receptor Activity

...uron. Both, erbB4 and NMDA receptors, are bound to scaffolding proteins called post-synaptic density (PSD), which can bridge receptor groups together and enhance their interactions. ‘PSD proteins can act like a raft in the ocean,’ explains Hahn. ‘Just as holding onto a raft increases one's chance of survival, ...

Researchers Find Molecular "Brake" to Cell Death

...-1 in the cell cytoplasm, and together they form a scaffolding "death wheel" to activate enzymes called caspases that shred a cell apart. But what they also believed is that a cell needs extra energy from ATP to undergo apoptosis, and that this extra energy was produced from the "pools" of free nucleotides tha...

Craniofacial Surgery Gives Tijuana Teen Chance to be 'Normal' Kid

...o create a type of scaffolding. We then coated the scaffolding with a material made of hydroxyapatite (the primary mineral component of bone), commonly called ‘bone paste’ or ‘bone cement’ that functions much like bone.” Urata and Danielpour reconstructed Lozano’s right eye socket to hold an eye prosthesis (w...

More Stress, More Cancer

...MP-2 and MMP-9 -- play a role in breaking down the scaffolding that cells attach to in order to maintain their shape. The third compound, vascular endothelial growth factor (VEGF), is important in the growth of new blood vessels into tumor cells. Earlier work by researcher Anil Sood at the University of Texas...

Cellular Pathway Yields Potential New Weapon in Vaccine Arsenal

...d to them by major histocompatibility compex (MHC) scaffolding molecules on a cell’s surface. Antigens on MHC class I molecules are recognized by killer T cells and had originally been thought to come only from sources inside a cell (proteins from the nucleus or other cellular part); those on MHC class II molecu...

Researchers Discovered the Gene Responsible for Brittle Bone Disease

...pe I collagen, which serves as a kind of molecular scaffolding that holds together bone, tendons, skin and other tissues. The collagen defects result from dominant mutations, requiring only one copy of a mutant gene to cause bone disease. The NIH researchers discovered that mutations in the CRTAP gene accounted ...

Workplace Pressures, Hazards Raise Risk of Job Injuries in Youths

...hazards included using knives, climbing ladders or scaffolding and operating fryer machines, grills and ovens. Unsurprisingly, the more hazards workers were exposed to, the greater their likelihood of injury. A consistently increased risk of injury also existed among youth who reported feeling overloaded or ...

U.S. Child Health System Needs Total Overhaul

...n increasing body of science now tells us that the scaffolding for our adult physical, cognitive and socioeconomic health is built in the early years of life,” said Halfon, who prepared the report with Dr. Helen DuPlessis, UCLA adjunct assistant professor, and Moira Inkelas, UCLA assistant professor, both with t...

U.S. Child Health System Needs Total Overhaul

...n increasing body of science now tells us that the scaffolding for our adult physical, cognitive and socioeconomic health is built in the early years of life,” said Halfon, who prepared the report with Dr. Helen DuPlessis, UCLA adjunct assistant professor, and Moira Inkelas, UCLA assistant professor, both with t...

New blood test to detect prostate cancer

... protein that is part of the 'nuclear matrix,' the scaffolding inside a cell's nucleus that helps it copy its genes. A team led by Robert H. Getzenberg, professor of urology and director of research at the James Buchanan Brady Urological Institute at The Johns Hopkins University School of Medicine tried the n...

Blood Test Reveals Colon Cancer Proteins

... Johns Hopkins scientists say they are part of the scaffolding that supports structures within a cell's control center, the nucleus. Alteration of such nuclear scaffolding is a hallmark of cancer cells that is easily detectable under the microscope as a misshapen and disc...

Why Malaria Parasite Affects Red Blood Cells Deformability Revealed

...l membrane, it binds to the cell's cytoskeleton--a scaffolding of proteins that lies just inside the cell membrane. In future studies, the researchers plan to study the effects of proteins produced by the malaria parasite during later stages of infection. They also plan to look at whether the RESA protein play...

Tissue Engineered Scaffolding Allows Reproduction of Cartilage Tissue

A new study examines the use of tissue-engineered scaffolding made of cartilage cells, which have a limited abil... for implantation, did not occur in the study. The scaffolding allowed the newly grown cartilage to maintain its volume during cultivation and post-procedure. Th...

Hong Kong's Shopping Spree Surges On, and on

...'s bustling Tsim Sha Tsui tourist district, bamboo scaffolding stretches like a web over a swathe of reclaimed land surrounded by tower blocks. It's a seemingly unpromising piece of real estate, but by the end of this year should be home to a massive new complex devoted to Hong Kong's favourite obsession -- s...

Research in the Origin of Microtubules

...thought that microtubules, part of the microscopic scaffolding that the cell uses to move things around in order to hold its shape and divide, originated from a tiny structure near the nucleus, called the centrosome. The findings point to a novel cellular mechanism that may guide cell movement and possibly ca...

Scientists Have Discovered Blood Protein That Could Spot Colon Cancer

...olorectal cancer patients. Alteration of nuclear scaffolding is a hallmark of cancer cells that is easily detectable under the microscope as a misshapen and discoloured nucleus. This led the researchers to the notion that there must be something at the molecular level that would form a molecular flag for cance...

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