Gene Defects Determine Susceptibility to Cancer and Bone Marrow Failure
...o's laboratory focuses on understanding control of ribosome activity and how disruptions in RNA translation pr...e results from a gene mutation, Dkc1, that affects ribosome function. Dyskeratosis congenita involves abnormal bone marrow leading to anemia, immune deficienc...Yale Scientist Received Medical Science Prize From Keio University
...” said Steitz. Many antibiotics work by blocking a ribosome function that stops bacteria from propagating by interfering with their ability to make proteins. The work of Steitz and his Yale colleague Peter B. Moore, Sterling Professor of Chemistry, shed light on the specific molecular interactions involved be...The ribosome is the protein-producing nanomachine in cells that...provided a clue that could lead to programming the ribosome to fight viruses like HIV AIDS and SARS. In the March 23 issue of the journal Molecular Cell, Univ...