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Tag: "regulates" at medical news

First Target For Stem Cell Research Will Be Diabetes Cure

... have the cells in the petri dish, we can see what regulates the disease, how we can understand the disease process and how we can go through drug discovery. We can do it in the petri dish, rather than in human or animal tests,' – said Dr Sidhu. Embryonic stem cells have the potential to become any kind of ...

Tougher Fiber Dental ‘bridges’ for a Brighter Smie

...the U.S. Food and Drug Administration (FDA), which regulates dental composites as class II prescription devices. The agency requires eight minimum tests plus biocompatibility tests to ensure that dental composites are safe and nontoxic. 'Fiber-reinforced composites are now widely used in the aerospace and ...

How Taste-buds Develop?

...s. They have pinpointed a molecular pathway// that regulates the development of taste buds. Taste buds are the sensory organs that transmit chemical stimuli from food and other sources to nerve cells, which convey these signals to the taste centers in the brain. Taste buds sit in the small bumps in the surfa...

Altered Sodium Channel Function Linked to Heart Failure

...ing VTs. So, because a protein known as calmodulin regulates Na+ channel function, and expression and activity of the calmodulin effector CaMKII is upregulated in humans with heart failure, Maier and colleagues investigated the effect of CaMKII on Na+ channel function. In this study, which appears online on No...

Non-Steroidal Anti-Inflammatory Drugs Can Cause Liver Damages

...doesn't reach the lungs, where alpha-1-AT normally regulates enzymes that digest protein. Loss of alpha-1-AT's regulation of protein-digesting enzymes in the lungs can result in tissue damage and emphysema. In ways not yet entirely understood, accumulation of alpha-1-ATZ in the liver can lead to both liver d...

Effect Of Growth Factor Signals On Cancer Development

...ry said. He added, 'For years we've known that p53 regulates another binding protein, IGBFP-3, to inhibit IGF signaling, but now we know that was the tip of the iceberg, as p53 appears to regulate the IGF axis at multiple nodes. It took collaboration between an endocrinologist and a medical oncologist to break...

GMC Wrestles For Regulatory Powers

The General Medical Council (GMC) that regulates all UK doctors welcomed a shake up in doctor regulation, though it had earlier objected some proposals //put forward by Sir Liam Donaldson, a medical officer of England. Officials say that GMC wants to retain adjudication powers in fitness to prac...

Patient Advised to visit Exorcist

...spirit. The General Medical Council (GMC), that regulates all UK doctors, will conduct an investigation into these allegations where Dr Pratt, is charged with acting in a manner that was 'irresponsible, unprofessional, intimidatory to her patient and liable to bring the profession into disrepute'. In add...

Cot Death Could Be Linked To Brain Defect

...orted the online edition of Daily Mail. Brain stem regulates breathing, blood pressure and body heat. Researchers suspect that the defect might affect the ability of babies to wake up when threatened by external problems such as excessive heat or carbon dioxide when they are face down in bed. "A normal bab...

New Asthma Medicine Targeting Vulnerable Inner-City Children Tested

...that’s there, decreases the receptors for IgE, and regulates many things that pertain to allergy and the asthmatic response,” Dr. Gruchalla said. The two-year Dallas portion of the study targets children 6 to 20 years old who reside within the Dallas Independent School District. Individuals interested in par...

Potential New Therapeutic Target for Asthma, Allergies and Cancer

...istry, and colleagues reported how S1P, which also regulates many important physiological functions in cells, is transported out of mast cells. S1P is produced by all cells and secreted by some cells into the circulation where it can bind to specific S1P receptors. Until now, researchers have not known the mec...

Gene Involved In Common Birth Defect Also Regulates Skin Biology

.... Detailed analysis of the mice revealed that IRF6 regulates the proliferation and differentiation of keratinocytes -- the main cell type in the epidermis or outer layer of skin. Keratinocytes also provide a protective barrier around the mouth, gut, liver, lung, kidney and other internal organs. 'This study ...

Levels of Thyroid Hormone Forecasts Life Span

...er is the life-span//. Thyroid hormone in the body regulates the metabolic rate. The study engaged in a comparative study of the levels of thyroid hormones in rodents that belonged to different groups and age groups as well. The study measured the thyroid levels for each animal. The finding revealed, there wa...

New Tool for Understanding Estrogen-Fueled Breast Cancer

...nced by the ER. "cis" refers to a DNA segment that regulates a gene’s activity in response to a signal from outside the gene (while "trans" refers to a factor that acts on DNA); and "ome" -- from the Greek word for manager -- refers to the full set of such segments, as "genome" refers to all the genes within h...

Brain behind the Brawn: Vital Molecule in the Brain Controls Appetite

...ns. The hypothalamus is a region of the brain that regulates appetite and temperature. The effects of this molecule were observed on rats; when the molecule was injected into the brains of rats, a feeling of fullness is created , which results in the rats eating much less. This also caused the animals to lose...

New Angiogenesis Finding May Help Fight Cancer Growth

...enesis. Instead, they were studying a protein that regulates the maturation of blood cells, and noticed that it...e to call it a master switch, but intriguingly, it regulates at least four different processes, each of which individually would be anti-angiogenic," says Bresni...

World's 3 out of 10 Cigarettes Smoked in China

...on Tobacco Control which bans tobacco advertising, regulates cigarette packaging, bans the sale of cigarettes to minor and bans smoking in work and public places. More significantly, however, Mackay believes there are signs on a social as well as a political level that awareness of the dangers of smoking is ...

New Path from Estrogen to Survival in Breast Cancer Cells Described

...roteins, the researchers say. "NEDD8 modified BCA3 regulates the activity of NFkB, but BCA3 alone does not have any impact on NFkB," says Yeh. Then they looked at how this NEDDylation further works to suppress the ability of NFkB to transcribe (activate) other genes. Here the investigators found SITR1, the m...

Appraisal of FDA’s Drug Safety Proces

...ure it upholds focus on the safety of the drugs it regulates throughout the time they are on the market. Cultural modifications are also required to prevent the tensions that can upset the evaluation of drugs' risks and benefits. Labeling and advertising restrictions on newly approved drugs are also needed t...

Molecular Medicine And Diabetes

...al genes that work together to form a channel that regulates the flow of potassium ions in and out of the insulin-producing beta cell. In the normal beta call, glucose metabolism results in increased levels of ATP, a molecule that cells use to store energy. The increase in ATP causes the potassium channel to...

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