A Novel Target for Type-2 Diabetes Atk2
... a protein, along with its molecular partner, that regulates fat metabolism. Over the last 10 years, we have begun to understand the importance of fat metabolism in diabetes, notes lead author Morris J. Birnbaum, MD, PhD, the Willard and Rhoda Ware Professor of Diabetes and Metabolic Diseases at Penn and an ...Pessimists may Develop More Memory Problems
...sponse. Unfortunately, that part of the brain also regulates memory.' An earlier study by Wilson and his colleagues showed that people who are easily distressed are more likely to develop Alzheimers disease than more easygoing people. Wilson said several factors lead researchers to believe that proneness t...FDAs Failure Urges It to Reassess Its Policies
... is exploring ways to overhaul how it inspects and regulates imported food. It is considering, among other actions, using risk analysis to try to pinpoint shipments that might pose hazards. Risk based inspections could reduce the time shipments but the proposals could require importers and manufacturers to pr...Scientists Identify Critical Gene Factor in Heart Development
... electrical conduction of the heart, which is what regulates the heart beat. Defects in the heart rhythm frequently cause sudden death in humans and are the reason for pacemakers and defibrillators. Loss of miR-1-2 also caused a breakdown of the control of cell division in the heart cells. This is potential...New Light on Working of Brain Networks
...d DISC1 (Disrupted in Schizophrenia) that normally regulates cAMP. Loss of function of DISC1 in patients with schizophrenia or bipolar disorder would increase vulnerability to cortical network disconnection and profound PFC deficits. This may be especially problematic during exposure to even mild stress, which...Brain Networks Strengthened by Closing Ion Channels
...d DISC1 (Disrupted in Schizophrenia) that normally regulates cAMP. Loss of function of DISC1 in patients with schizophrenia or bipolar disorder would increase vulnerability to cortical network disconnection and profound PFC deficits. This may be especially problematic during exposure to even mild stress, which...New Technology Reveals Proteins Responsible for Diseases
...s discovered that one of these interactors, Tus1p, regulates Ycf1p transporter function in a completely novel way to stimulate its ability to remove toxins from the cell. "The more we learn about membrane proteins, the better we can use this knowledge for pharmacological and clinical applications," Staglja...Brain Structured to Make Human Beings Religious, Claims a US Scientist
.... The limbic system, nestled deep in the center, regulates our emotions and is responsible for feelings of awe and joy.Newberg calls religion the great equalizer and points out that similar areas of the brain are affected during prayer and meditation. Newberg suggests that these brain scans may provide proof...New Genetic Biomarkers Could Predict Coronary Heart Disease
... Telomeres are also thought to be the "clock" that regulates how many times an individual cell can divide. Telomeric sequences shorten each time the DNA replicates. When the telomeres reach a critically short length, the cell stops dividing and ages (senesces) which may cause or contribute to age-related disea...Proteins in Microparticles Identified in Women With Preeclampsia
... released from the placenta contain a protein that regulates clot formation (plasminogen activator inhibitor-1). They also found that microparticles contain soluble Flt-1, which inhibits blood vessel growth, and that microparticles contain extremely high levels of plasminogen activator inhibitor-2, a placental...Researchers Discover Proteins That Protect Against Skin Cancer
...ins, named Timeless and Tipin, form a complex that regulates the rate at which DNA is replicated after exposure to ultraviolet radiation. Ultraviolet radiation in sunlight damages the DNA in skin cells. If left unrepaired by the cell, this damage can turn into mutations that lead to cancer. Before cells divi...Drug for Blood Pressure also Treats Lung Cancer
...) reduces cyclooxygenase-2 (COX-2), an enzyme that regulates cell growth. COX-2 is found at higher levels in 70 to 90 percent of malignant lung tumors. Theoretically, drugs to reduce COX-2 would also be effective at shrinking tumors. But the drugs, such as Vioxx?, have been shown to increase the risk of hear......ed over 5,000 compositions, told IANS. 'My music regulates the activities of the head and heart and helps eliminate stress and strain. Since human beings generally have an ear for music, they benefit faster this way in regard to various stress-related ailments,' he added. The patients are made to listen to...Caloric Restriction in Non-obese People Extends Life Span
...ctivation of the Sir2 gene increases life span and regulates cellular metabolism. An important question is whether caloric restriction can regulate SIRT1 (the mammalian equivalent of Sir2) in humans. Civitarese and colleagues found that indeed fewer calories can improve whole body metabolism in conjunction wit...Lactococcus Strain may Offer End to Food Allergies
...bacteria, bioengineered to produce a compound that regulates immune response in the gut, may offer significant potential// for beating food allergies, if results from an animal study can be translated to humans. Authors Christophe Frossard and Philippe Eigenmann from the University Hospital of Geneva in colla...Free Kidney Check Up Camp in Kasturba Hospital on World Kidney Day
... around 180 liters of our blood every day. It also regulates salts in our blood and keeps our body temperature and blood pressure under control. The intention of World Kidney Day 2007 is to make people aware that ‘kidney disease is common, harmful and treatable.’Chronic kidney disease is prevalent all over t...Targeting SOCS-3 can Control Obesity
...besity causes the breakdown of a brain system that regulates appetite. The study also points// to a key gene as...aking part in an important signaling function that regulates appetite and body weight. Meanwhile, other portions of the weight regulation system remained intact ...Insights into Osteosarcoma in Cats and Dogs may Improve Palliative Care
...n (OPG). RANK is one of a family of receptors that regulates bone and immune homeostasis. In health, RANK, RANK-L and OPG together keep the continual process of bone growth and resorption in balance. Bone tumors presumably derail this homeostatic process, however, by upregulating RANK-L expression. RANK-L b...Leukemia Drug Turns Mini-Molecules Up, Cancer Genes Down
...expression of these three miRNAs, and through them regulates genes that need to be silenced for the cell to differentiate.” Funding from the National Cancer Institute, the Paul and Mary Haas Chair in Genetics, a Lauri Strauss Discovery grant award, the Kimmel Foundation and the CLL Global Research Foundatio......shows that receptor protein tyrosine phosphatase T regulates an important signaling pathway that is critical in cancer development. This identification will allow new approaches to pharmacological designs and facilitate alternative approaches for cancer treatment." Source-Bio-Bio Technology...