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Tag: "refractory" at medical news

ECP may Be Effective in Treating Crohn's Disease

...tomatic) Crohns disease who cannot tolerate or are refractory to immunosuppressants and/or anti-TNF agents. A 50% response rate after 3 months of ECP treatment was noted in the study, using standard disease activity criteria, as presented this afternoon at a scientific research session of Digestive Disease Week...

Bronchial Thermoplasty: Boon to Severe Asthma Patients?

...wing bronchial thermoplasty, patients with severe, refractory asthma demonstrated significant improvements in pu... trial provide some hope for patients with severe, refractory asthma people who despite taking state-of-the-art medications are still experiencing the disruptive...

Amrubicin Shows Encouraging Results for Small Cell Lung Cancer Treatment

... patients; one as single-agent therapy in patients refractory to first-line therapy; and one as single-agent or combination therapy with cisplatin versus cisplatin plus etoposide in previously untreated extensive stage patients....

New Therapy to Treat Patients With Severely Elevated Cholesterol Levels

...l hypercholesterolemia (FH), a high-risk condition refractory to conventional therapy, had a remarkable 51% reduction in low-density lipoprotein (LDL) or “bad cholesterol” levels. "Our study shows that targeted inhibition of the microsomal triglyceride transfer protein (MTP) is highly effective in reducing ch...

Hope For Bedwetting Children

...nal polyuria in monosymptomatic nocturnal enuresis refractory to desmopressin treatment,” was carried out by Konstantinos Kamperis and Jens Christian Djurhuus of the University of Aarhus, Aarhus, Denmark and Soren Rittig and Kaj Anker Jorgensen of the Aarhus University Hospital. The study appears in the Decembe...

A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers

...one-na?ve metastases, and in 33 percent of hormone refractory metastasis, as well as in about 20 percent of prostatic intraepithelial neoplasias, a lesion believed to be precursor of invasive prostate cancer. The investigators also discovered that the gene fusion could occur in two different ways. The genes,...

'Good' And 'Evil' Clones Of Acute Lymphoblastic Leukaemia cells

... due to small numbers of surviving and highly drug refractory cells. However, until now, it has been unclear whether these relapses resulted from the acquisition of therapy-induced drug resistance or were caused by a subpopulation of cells that were already intrinsically drug resistant.' Ms Choi, a final year...

Partial-match cell transplants for kids with resistant leukemia

...chnique with results from a group of patients with refractory blood cancers who were treated with MCR. The investigators reported that following RICR in 22 children, 91 percent achieved full donor chimerism; that is, the recipients "adopted" the transplanted stem cells and built a blood system that was identica...

Monoclonal Antibody Reduces Exacerbations in Asthmatics

...a soluble receptor directed against TNF? in severe refractory asthma have also shown improvements in lung function and airway hyperresponsiveness.” During the study, 13 of the 18 patients on placebo (72 percent) experienced exacerbations, as compared to only four out of 14 patients (29 percent) on infliximab ...

Heart Treatment from Vasogen Shows Promise

... to late-stage disease, at which point they become refractory to intervention. We are looking at a very broad population." The recent review showed that Celacade helped patients with class II chronic heart failure, according to the assessment by the New York Heart Association as well as the more ailing class ...

Dealing with IBS

...d in IBS patients with moderate to severe symptoms refractory to physician counseling and dietary manipulations. New therapies for IBS have been recently introduced and have been shown to effectively treat multiple symptoms of IBS....

Sunitinib a Promising Agent for Treatment of Renal Cell Cancer

...s with metastatic clear-cell RCC whose disease was refractory (unresponsive) to 1 prior cytokine therapy. Patients were enrolled between February and November 2004, with follow-up continuing until disease progression, unacceptable toxicity, or withdrawal of consent. Patients received repeated 6-week cycles of...

Prostate cancer drug not found cost-effective

... the treatment of patients with metastatic hormone refractory prostate cancer (MHRPC)”. Source: BBC News....

Prostate Cancer Preventable By Vitamin D Analogs

...fect of calcitriol and QW was not found on hormone refractory prostate cancer in castrated mice. "Our pre-clinical data using the TRAMP mouse model, which mimics human prostate cancer, suggests that calcitriol and QW-1624-F2-2 are promising for prevention of androgen-dependent prostate cancer progression," sa...

Bortezomib for salvage therapy against progressive myeloma

...up of MM patients induced by AuSCT and relapsed or refractory after thalidomide employed as second line treatment (first salvage therapy). For the study to be published in the journal Leukemia Research (available online 18 August 2005), twenty-one patients with multiple myeloma, all relapsed after frontline a...

A New Approach In Treatment Neurogenic Detrusor Overactivity In Children

...urred. Patients with difficult bladder conditions refractory to anticholinergic drugs have traditionally undergone immediate surgical procedures, such as bladder augmentation. However, according to this new study, BTX-A detrusor injection offers a reliable alternative and protects some of those difficult-to-tr...

Response to chemotherapy could be measured by Prostate-Specific Antigen Doubling Time

...esponse to chemotherapy// in patients with hormone refractory prostate cancer. The study was carried out with forty men who had hormone refractory prostate cancer and bi-dimensionally measurable metastases in the lymph nodes or visceral organs. Th...

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