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Tag: "protein" at medical news

Soy Products a Double-edged Sword for Breast Cancer

...s in soy products or ingredients such as tofu, soy protein isolates, soy flour and some estrogenic dietary supplements. Genistein is of interest because it is the most active of the soy isoflavones, and because it activates estrogen receptors in cells, including some breast tumour cells. Dozens of studi...

Study Implicates Protein as a Trigger of Advanced Prostate Cancer Recurrence

...first time implicated a growth-promoting cellular protein as one trigger of the inevitable recurrence of adv...osphorylation by adding a phosphate group to this protein molecule. "This biochemical action converts a prostate cell that would need an androgen signal for...

New Analytical Tool to Unravel the Cause of Diabetes

...offer a glimpse into the contorted form of a human protein that is implicated in type II diabetes. Pancrea...II diabetes has been linked to toxic clumps of the protein hIAPP (human islet amyloid polypeptide), which is normally produced by the same cells that make insu...

Pregnancy Becomes Safe for Some Women Who Take Low-dose of Aspirin Daily

...ncrease in blood pressure and excessive amounts of protein in the mother's urine, and can prove fatal to mother and baby. Askie believes anti-clotting drugs protect pregnant women by reducing inflammation or preventing blood clots from forming. "Whilst the benefits of anti-clotting therapy are modest, th...

Suicide Gene Therapy Kills Bowel Cancer Cells

...When the gene is switched on, the virus produces a protein that activates an otherwise harmless prodrug, give...ls are spared because the virus doesnt produce the protein that activates the drug unless it is inside a tumour. "The beauty of our approach is that the canc...

Scientists Develop Method to Track Immune System Enzyme in Live Animals

...eated transgenic mice that had a green fluorescent protein derived from jellyfish fused to the AID enzyme. In...workers expressed permanently a yellow fluorescent protein in the progeny of germinal center B cells. Thanks to these new mouse models, we can track in live an...

Scientists Map Genome Sequence Dengue Mosquito

...helped validate 80 per cent of the15,419 predicted protein coding genes in Ae. aegypti. "An important part...re Ae. Aegypti genome. "Although the majority of protein coding TE copies in Ae. aegypti appear to be degenerate, a significant number of elements have poten...

AIDS Vaccine Still a Long Way Off

...le that grants HIV entry into those cellsa surface protein called gp120, which inserts itself into CD4 receptor molecules on the helper cells. Early tests of a gp120 vaccine looked promising, but optimism faded by the early 1990s as researchers learned the vaccine only worked against strains of HIV that h...

Role of Protein in the Development of Prostate Cancer Identified

Recent studies have indicated that the protein known as TRPM8 plays an important role in prostate cancer: high levels of TRPM8 have been found in prostate carcinoma compared to normal prostate epithelial cells, and TRPM8 has been suggested as a specific marker and therapeutic target in prostate ...

Combining NSAIDs With Chemotherapy May Improve Cancer Therapy

...celecoxib exerts its anticancer effect by altering protein expression in ways that disrupt the cell cycle and...eins and significantly decreases the activity of a protein called E2F1. This activity is required for cells to move through the cell cycle and also is crucial ...

Protein Folds Research Offers Insight into Metabolic Evolution

... created the first global family tree of metabolic protein architecture and their advance offers a new windo... been used to work out the evolutionary history of protein architecture across biological networks. We are interested in how structure evolves, not how organ...

Vegetarian Diet Could Reduce Risk of Colon Cancer

...e lab for two sessions (eating both fatty soup and protein soup with the same number of calories and volume)....her in a social setting. When compared with the protein soup, the fatty soup considerably abridged the amount of caloric intake with the following meal in b...

Wrinkles can Be Really Ironed Out, Thanks to Vitamin A

...e age, their skin produces less collagen, the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% of the total protein content. Consequently the skin tends to becom...

Scientists Create Synthetic Proteins

...he adds. Chaput said that the test tube derived protein was not only stable, but could bind its target mol...art this random process and relate it to the final protein function," said Chaput. The study has been published in the journal PLoS ONE....

Scientists Use Gene Therapy to Reverse Heart Failure in Animals

...h and his team found that increasing levels of the protein S100A1 above normal helped protect animal hearts f... animals with heart cells lacking the gene for the protein couldn't handle the stress of part of the heart dying and went on to develop heart failure. S100A1...

Circadian Clocks Triggered Chemical Reactions may Be Behind Jet Lag

...iolet radiation just after sunrise. They studied a protein called vivid, which contains a chromophore, a ligh...an now show that this conformational change in the protein is directly related to its function in the organism," said Brian Zoltowski, the paper's lead author ...

Gene Discovery Lays Groundwork for Targeted Therapies for Endometrial Cancer

...not have these mutations. The FGFR2 gene encodes a protein that plays a critical role in cell growth. In pati...s, the tumors were caused by the receptor for this protein being permanently stuck in the "on" position. "Mutations in several genes have previously been ide...

Research may Yield Improved Treatment for Diseased Lungs

...collagen, the body's ubiquitous fibrous structural protein that strengthens blood vessels. Patients with certain kinds of scleroderma also contract a kind of pulmonary hypertension that is particularly resistant to most treatments. So in a limited series of studies in such patients, Chesler also will inves...

Robotic Surgery May Improve Survival Rate For Prostate Cancer Patients

...hances that the prostate-specific antigen (PSA)- a protein produced by the cells of the prostate gland - will rise after surgery, and increase the chances that the disease will reoccur and progress, said Edouard Trabulsi, M.D., assistant professor of Urology, Jefferson, a urologic oncologist and an expert tr...

Scientists Identify New Breast Cancer Gene

...chers found Rap80 binds to the region of the BRCA1 protein that is necessary for recognising sites of DNA dam...e. They say that cancer-causing mutations in the protein fail to bind to the Rap80 protein, disabling BRCA1 to identify DNA damage sites in the genome. As a ...

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