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Tag: "protein" at medical news

New Engineered Drug Shows Promise in Treating Lymphocytic Leukaemia

.... This agent, which is called CD37-SMIP, targets a protein called CD37 on the surface of these leukemia cells...hows that the agent can successfully attach to the protein on the leukemia cells and destroy them. It works both by activating the cells' self-destruction and ...

Depression Drugs Could Make Bones Fragile

...in Portland. The researchers say SSRIs inhibit a protein that transports serotonin, a chemical messenger involved in sleep and moods. The protein has also been discovered in bones, raising the possibility that the drugs may affect bone strength. ...

Proteins Behind Mad Cow Disease may Protect Against Alzheimer's

...ous prions corrupt the normal version of the prion protein present in brain cells, causing them to change the...s. They found that the build-up of beta-amyloid protein was reduced when the levels of prions were high in the brain. Whereas, the formation of plaques went...

First Bacterial Genome Transplantation Changing One Species to Another

...eam used two methods -- 2D gel electrophoresis and protein sequencing, to prove that all the expressed proteins were now the ones coded for by the M. mycoides LC chromosome. Two sets of antibodies that bound specifically to cell surface proteins from each cell were reacted with transplant cells, to demonst...

Allergic Individuals Should Keep Away from Cats, Say UK Scientists

...or your lungs. UK researchers have found that a protein secreted from the cats skin could irritate the lungs and exacerbate the symptoms of asthma, even in people who have no specific allergy to the animals. Of course the problem is restricted to individuals who generally suffer from allergy of one kind o...

RNA Play a Vital Role in Gene Activity

...to turn genes either on or off, depending on their protein partners." But then Rinn looked more deeply. The fact that the ncRNAs have remained virtually unchanged over millions of years suggests they may be playing non-traditional but vital roles in gene expression. The researchers found that depleting ...

Scientists Identify New Possible 'biomarker' for Pancreatic Cancer

...said. During the study, the researchers used the protein HGFL to activate the RON receptor. They observed that though stimulating the RON receptor had no effect on pancreatic cell growth, blocking it with targeted antibodies killed more cancer cells than did the standard treatment drug gemcitabine alone...

Vaginal Lubricants can Reduce Cervical Cancer Risk

...by forming an HPV 'pseudovirus' which had the same protein coat as HPV but a different genome, and could replicate in cell cultures. The pseudovirus was also marked with a fluorescent tag, which enabled scientists to follow the growth of infection. "The pseudovirus mimics the initial phases of infection...

Boffins Identify Molecule That Might Treat Food Allergy

... food allergy the immune system responds to a food protein as if it was harmful. The immune system produces immunoglobulin E (IgE) antibodies, which normally help the body fight parasites. In the most severe cases individuals can suffer life-threatening reactions, including anaphylactic shock. The study w...

Potential Target for Allergy Therapy

...ions could be brought back under control. A food protein can be perfectly harmless to one person and lethal...gy means that the immune system responds to a food protein as if it was harmful. The immune system produces immunoglobulin E (IgE) antibodies, which normally h...

Gene Responsible for Ageing Process Discovered and Calorie Restriction Could Help

...his colleagues is known as PHA-4 - the name of the protein for which the gene is responsible. The same gene also exists in mice and humans and is known as the Foxa family of genes. Both PHA-4 and Foxa are involved in the complex process of glucose metabolism. In mammals, the gene is linked with a hormone cal...

Malfunction of Gene Causes Schizophrenia, Depression

...d biochemical abnormalities in the function of the protein produced by the DISC1 gene. The researchers concluded that the different effects of anti-psychotic and antidepressant drugs on the two mutant strains "might provide clues to effective medications for these patient groups. "Indeed, these mice cou...

Protein Reduction Ceases Alzheimer's Advancement in Mice

Reducing the levels of a protein called tau helped in the reduction of Alzheimers s... of brain cells. In patients with Alzheimer's, the protein gets entangled forming knots. There have been many treatment approaches that target to dissolve thes...

New Clues for Treatment of Disease That Causes Accelerated Aging

...rn about lamin A. When appropriately produced, the protein becomes part of a meshwork between DNA and the nuc...ked. "It's a matter of ratios: the more abnormal protein you have, the more severe the disease," Miner says. "And apparently we don't have that far to go to ...

Vaccine Prevents Prion Disease in Mice

...dementia and abnormal limb movements. Prion is a protein that is also an infectious agent. The proteins are so similar to proteins found normally that the immune system does not fight them off. To develop a vaccine that would stimulate the mice's immune system, researchers attached prion proteins to a gene...

Cause of Gender Differences in Blood Pressure, Kidney Damage Under Study

...inds about a 50 percent increase in the amount of protein excreted in the urine - a sure sign of kidney disease - in the males. She notes that by age 70, the rates of cardiovascular disease and hypertension are similar in men and women and that older women tend to have higher blood pressures than age-ma...

Novel Technology to Locate and Treat Tumors

...d potentially treat tumors using a short piece of protein that acts like a nanosyringe to deliver tags or th...my of Sciences. The researchers show that, the protein fragment, called pHLIP (pH (Low) Insertion Peptide) can be injected into the abdomen of a mouse, fin...

New Technique Dissects Stem Cells' Picky Likes, Dislikes

... To this end, the researchers tethered 18 distinct protein fragments, known as peptides, to the surfaces of s...des her team chose to test first come from a major protein component of the ECM called laminin. Laminin also makes up about 60 percent of Matrigel, an extract ...

Preserving Kidneys on a Pump May Promote More Organ Sharing

...igh blood pressure, stroke or elevated levels of a protein called creatinine. Levels of creatinine, which is produced by muscle, are used to determine kidney function. The current study included 120 ECD kidney transplants -- 95 kidneys were preserved with machine and 25 with simple cold storage preservatio...

Diet for Autism

...ous quarters that a diet free of gluten (plant protein found mostly in wheat, rye and barley) and casein (protein found in dairy products), induced symptomatic improvements. But these claims are based on hope, lack factual basis and fall short of the required scientific evidence. Early studies ...

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