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Tag: "protein" at medical news

Researchers Identify New Risk Marker for Obese Children

...ne of them has high levels of apoB48, a structural protein found in intestinal cholesterol. The children presented high levels of apoB48 even as their LDL cholesterol levels, which are characteristically high in overweight adults, remained in the normal range. In discovering high levels of apoB48 in the...

Vaccines That Kick Drug Habits, Minimize Withdrawal Symptoms Developed

...ccines spur antibody production, each has a unique protein composition that help the body target the different drugs. Researchers insisted that while the vaccines have shown to help overcome drug addictions, they do not necessarily curb relapse. This is not a stand-alone treatment. There is a reason drug...

Scientists Develop Insulin Pill

... for a British company has developed a form of the protein that can be taken orally. Scientists at Diabetology, a small research and development company that has spent may years trying to develop oral insulin, believe that it will better control of symptoms. The company has successfully enclosed the ins...

Research Studies on Molecular Switches of Gene

... Childrens Research hospital . The on switch, a protein called CREB, is a transcription factora molecule t...a gene and triggers that gene to make the specific protein for which it codes. CREB activates genes in response to a molecule called cAMP, which acts as a mess...

Protein Targets for Carcinogenesis

...f cancer and other diseases. Our current view on protein ubiquitination as it is found in the textbooks has...his includes fundamental cellular programs such as protein degradation, DNA replication, signal transduction or protein trafficking. Up to now it was believe...

Gene Therapy for Parkinsons Disease

...of fluid containing a viral vector and genes for a protein called GAD, glutamic acid decarboxylase. This enzyme is critical in controlling a neurotransmitter called GABA. In Parkinsons, GABA is reduced in an area of the brain called the subthalamic nucleus. This region is working on overdrive in the diseas...

Researchers Link Bacteria Destroying Proteins to Alzheimer's Treatment

...goals of such treatments is to destroy clumps of a protein called beta amyloid, which are found in the brains... bind to the surface of the cells and connect to a protein called amyloid precursor protein (APP), which is already present on the cell surface. Then both prot...

Researchers Devise New Compound to Treat Fungal Infections

...ion in nails by blocking an enzyme crucial for the protein synthesis of fungal pathogens. The study was con... code, called messenger RNA. Ribosomes, the cell's protein synthesis machinery, then translate the messenger RNA into protein by stitching together the amino a...

More Fat Leads to Less Coronary Artery Calcification

...se these mediators suppress a type of inflammatory protein called tumor necrosis factor alpha (TNF-alpha). TNF-alpha is found in one type of cell, called microglia, that can be closely associated with retinal blood vessels. The retina has one of the highest concentrations of omega-3 fatty acids in the body...

Ancient Ancestors Might Have Had a Clue to HIV

...ey found that the human version of the TRIM5-alpha protein could bind to the virus, labeling it for the cell ... attaching to the ancient virus. This antiviral protein appears to be able to fight one virus or the other. Early humans evolved a defense against PtERV1,...

Chronic Metamphetamine Abuse is Related to Cardiovascular Disease

...heimers disease. Long-lived AGEs can easily modify protein function, initiate adverse cellular reactions, and form damaging deposits on arterial walls. Methamphetamine-AGE proteins not only increased antibody production, the study said, but were strong enough to overcome the drugs natural immunosuppressiv...

Common Antidepressants Linked to Increased Bone Loss in Older Adults

...ibitors (SSRIs) treat depression by inhibiting the protein that transports serotonin, a neurotransmitter involved in sleep and depression, according to background information in the articles, and which has recently been discovered in bone as well. The findings raise the possibility that SSRIs, which are of...

First Gene Linked to Scoliosis Identified

...han it should be, which reduces the amount of CHD7 protein produced. "The change in the amount of the protein produced is subtle, which correlates with the onset of scoliosis, which typically happens very gradu...

Researchers Reverse Mental Retardation Symptoms in Mice

...ntified a key enzyme, a chemical reaction-inducing protein as a possible target for an FXS drug. The enzyme, called p21-activated kinase, or PAK, affects the number, size and shape of connections between neurons in the brain. Researchers found that halting PAK's enzymatic activity reversed the structural a...

Antidepressents may Lower Bone Density in Older People

...ibitors (SSRIs) treat depression by inhibiting the protein that transports serotonin, a neurotransmitter involved in sleep and depression. This protein has recently been discovered in bone as well, raising the possibility that SSRIs may affect bone den...

Study of Bacterial Pathogen may Give Insight to Cancer Development

...r Keith Ireton, had recently found that a Listeria protein called InlB induces internalisation and degradatio...t internalisation and degradation requires a human protein called Cbl. The researchers feel that the knowledge of how to control Cbl may lead to the develop...

Reduced Lung Capacity Linked to Cardiovascular Disease by Inflammation

...lammation, they looked at the amount of C-reactive protein (CRP), an inflammatory marker, circulating in the blood. Higher levels of CRP were found in the blood of those with smaller lung capacities. Although increased levels of markers for inflammation have previously been found in the blood of older peop...

British Scientists Develop Artificial Skin

...s responsible for the production of collagen - the protein that gives skin its strength and elasticity. Using a series of chemicals, the fibroblasts - obtained from an anonymous donor - are coaxed into multiplying and producing collagen. After six or seven weeks, the cells and collagen knit together to fo...

Chilean President's Cousin Successfully Tests Allergy 'Knockout' Technique on Mice

... study has led to the identification of a receptor protein on mast cells, termed CD300a, which has a prominen...m unleashing allergic responses. The identified protein receptor is widely found throughout the immune system and, just like steroids, targeting it could re...

Boffins a Step Closer to Solving Puzzle of Lou Gehrig's Disease

...mists may have solved an important mystery about a protein that plays a key role in a particular form of amy...sor of chemistry and biochemistry, has studied the protein copper-zinc superoxide dismutase since the 1970s, long before it was implicated in ALS in 1993. S...

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