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Tag: "protein" at medical news

Combination of Tratuzumab and Chemotherapy Yields Better Results for Breast Cancer

...l breast cancers express large amounts of the HER2 protein or carry multiple copies of the HER2 gene. Those cancers tend to be associated with aggressive disease, a higher likelihood of recurrence and a decreased response to treatment. Trastuzumab is a monoclonal antibody that directly targets part of the HE...

Prions Capacity can Be Aggrevated by Solid Particles

...n prion expert Judd Aiken reports that prions, the protein agents of a family of fatal brain disorders, bind ...rate of infection.Prions are an abnormal form of a protein produced normally by the body. Tough as nails, they can persist in the environment for long periods ...

Protein Instrumental to Brain Development and Repair Identified

...ional Medical Center have identified a fundamental protein that is instrumental in the development and repair...ity of the epidermal growth factor receptor (EGFR) protein is significant for myelination and remyelination, the processes essential to the creation and repair...

First Genetically Engineered Maize Resistant to Maize Streak Virus Produced in S. Africa

...y of Cape Town mutated a viral gene that encodes a protein that the virus needs to replicate itself and inser...maize will also be tested to ensure that the viral protein is digestible and non-allergenic....

Study Confirms Benefits of Chemo, Trastuzumab Combo to Battle Breast Cancer

...l breast cancers express large amounts of the HER2 protein or carry multiple copies of the HER2 gene. Those cancers tend to be associated with aggressive disease, a higher likelihood of recurrence and a decreased response to treatment. Trastuzumab is a monoclonal antibody that directly targets part of the...

Obesity Drug may Hold Potent Cancer Treatments

...laboratory . The drug binds and interacts with a protein found in tumour cells and blocks the protein's fun... to stop tumour growth. Researchers found that a protein known as fatty acid synthase was expressed at high levels in prostate tumour cells, and was fairly a...

Specific Protein is Instrumental in Myelination

...ter have demonstrated conclusively that a specific protein and its signaling activity are instrumental in my...s study used mouse models to identify an essential protein and its signaling activity in the processes of myelination and remyelination. These processes are re...

Mutated Gene Zaps Pancreas Cancer in Mice

...an cancers The mutant gene named Bik expresses a protein that forces cancer cells to kill themselves, researchers from The University of Texas MD Anderson Cancer Center said. The team even created a more lethal mutant, called BikDD, which spares healthy tissue. "There are no good options for pancreatic...

Gene Therapy Eradicates Pancreatic Cancer in Mice

...ant version of a gene named BiK, which expresses a protein that naturally forces cancer cells to kill themselves, in two different types of mice. Boffins created the more lethal mutant and named it BikDD. Untreated control mice in both experiments all died within 40 days, while mice treated with the mutant...

Scientists Identify New Genetic Mutation Behind Common Dementia

...omosome 17 halves the production of progranulin, a protein growth factor that helps brain cells survive. For the study, the researchers conducted DNA tests on 70 family members, including 13 people with the disease. They found the new mutation in nine of the family members with frontotemporal dementia, and...

Smoking Speeds Up Muscle Loss

...non-smokers. To measure the synthesis of muscle protein they were given an intravenous infusion of blood w.... This measured the rate of synthesis of muscle protein which contributes to the daily maintenance of the muscle mass. The researchers found that it was sub...

Completely Neutral Evolutionary Changes Helped Shape Our Genome

...contained the blueprint (an actual gene) to make a protein that does anything, nor did they seem to control the function of any nearby genes. "At best, it seems numts are a neutral part of our genome. If anything, they may be mildly negative since long repeat sequences can be unstable or get inserted insi...

Penguins Altered Diet When Humans Began Hunting Whales and Seals

...attractive food for penguins because it is high in protein and tends to travel in swarms. "The birds can capture lots of high-energy prey in a short time," says Emslie. Ernslie and Patterson analysed over 220 fossilised eggshells, ranging from 100 to 38,000 years old, and compared them with samples from mo...

Plant Growth Regulated by Both Internal Clock and External Light: Study

... The PIF 4 and 5 genes are "switched on" to make protein during the day, switch off after dark but then turn on again late in the night. But the proteins made by PIF 4 and PIF 5 break down when exposed to light. o while the internal clock drives transcription of the genes to produce proteins, external ligh...

Insights into Acute Promyelocytic Leukemia

...cation between two chromosomes and gives rise to a protein called a fusion protein. In APL, the fusion prot...hought to play a role in the ability of the fusion protein to bind to DNA and regulate gene expression. Dr. Chi Wai Eric So from The Institute of Cancer Rese...

Simple Blood Test May Predict Alzheimers Disease

...lows a study by the team last year, which compared protein levels in the blood of 500 Alzheimer's sufferers with those of healthy older people. They were able to identify which proteins were present in higher quantities in those with Alzheimer's. In any case, the proposed blood test would be an improvemen...

Scientists Identified Obesity Control Switch

...ing to the new report, is controlled by a gene and protein known as PRDM16 that is found in brown but not in white fat -the type that stores excess calories and causes waistlines to bulge. In some of the mouse experiments, the Dana-Farber investigators inserted PRDM16 genes into precursors of white fat, an...

Smokers may Develop Chronic Obstructive Pulmonary Disease

...ene is responsible for the production of the IL-13 protein that is involved in pulmonary inflammation and sus...standing more about the role of IL-13 in COPD, the protein may one day be a target for new drugs for the disease. The variant has been shown to be associated ...

Insulin Sensitizer- Energy Conserving Signal to Brain

...ate fat stores during lean times . A fat-derived protein known for its effects on the liver and skeletal mu...ctivity of a metabolic enzyme called AMP-activated protein kinase (AMPK) to stimulate greater food consumption. Moreover, the researchers found that adiponec...

Cell Toxin Inhibits Survival Protein in Cancer Cells

... Bcl-2 proteins. Higher expression of the target protein made cells more sensitive to the 2-Methoxy antimyc...o certain proteins, so just by over expressing the protein the cell changes so that it cant live without that protein. The next step in this research is to u...

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