protein 1 10

Tag: "protein" at medical news

Long-term Use of Herceptin Does Not Increase Heart Failure in Patients

...se who have abnormally high levels of the HER2/neu protein for five years. Study participants were initially randomized to receive four cycles of a standard combination chemotherapy regimen, doxorubicin and cyclophosphamide followed by paclitaxel, or doxorubicin and cyclophosphamide followed by paclitaxel a...

Recurrent Gliomas: Vorinostat Shows Anti-cancer Activity

...d with vorinostat prior to surgery, and a gene and protein analysis of their resected tumors was performed. This analysis confirmed increase in histone acetylation and showed gene changes indicating that vorinostat reaches the glioblastoma tumors and interferes with the target pathways. Dr. Galanis says the ...

Scientists Discover How HIV Escapes Cells

...mal travel. Surprisingly, all thats needed for a protein to get out of the cell in exosomes are the ability...imilar exosomal deportation fate. The major HIV protein Gag has both of these properties that cells sense in selecting exosomal cargoes. Upon removal of ...

Reduced Oxygen to the Brain Increases Alzheimers Risk in Stroke Victims

...es could begin the increased production of a toxic protein called amyloid which builds up in the brains of people with Alzheimers....

Study Finds Lymphoma Drug Effective Over Long Term

...uided missile through the bloodstream to bind to a protein found on the surface of the cancerous cells. The radiation zaps these malignant cells with minimal exposure to normal tissues. With the Bexxar therapeutic regimen, a patient receives an injected test dose of radioactive Bexxar, followed one to two ...

Clinical Outcomes of Nonsmall Cell Lung Cancer Patients can Be Classified by New Algorithms

...agoya University in Japan, and colleagues analyzed protein patterns in NSCLC tumor tissue and normal lung tissue. The researchers identified a pattern that was associated with increased survival among NSCLC patients and may distinguish patients with poor prognosis from those with good prognosis. They also te...

Cancer Drug Induces HDAC Inhibitor and Enhance Long-term Memory

...d strengthen neural connections in the brain. A protein complex called chromatin causes genomic DNA to com... more easily. Previous studies have shown that the protein CBP causes chromatin to relax, thus facilitating gene activation required for memory formation. The ...

"Pre-treatment Blood Test" A New Guide to Lung Cancer Therapy

...oviding patient samples, set out to determine if a protein profile in the peripheral blood could predict clinical benefit measured in terms of patient survival to EGF receptor TKIs. Using mass spectrometry, the researchers analyzed pre-treatment blood samples from 139 patients who had been treated with g...

Breakthrough for Treatment of Fatal Heart Condition

... identify the mechanism behind specific changes in protein levels that impact upon cardiac cell size. Levels ...gh. Dr Ooi has found that an increase in a third protein in the body, known as REST, can halt the rise of the proteins causing cardiac hypertrophy, which, fo...

New Findings in Fragile X Mental Retardation Protein

...ss in understanding Fragile X mental retardation protein (FMRP), laying the groundwork for possible new tre...und that FMRP interacts with a nuclear mRNA export protein NXF2, in the mouse brain and testes. In this study, the team used mouse neuronal cells to explore th...

GAB2-A New Alzheimers Gene Identified

...n cells from Alzheimers patients and that the GAB2 protein produced by this gene is present in those brain cells containing tangles. When the researchers silenced GAB2 in preliminary studies it increased a molecular process thought to play an important role in the development of tangles. Based on these findi...

New Insights into Antimalarial Drug Resistance

...e PfMDR1 gene. They first obtained the PfMDR1 protein sequence from the NIH PubMed data base. They then back translated the protein sequence using a computer program to change the parasite gene sequence -- which combines nucleotide ...

A New Target for Cancer Therapy-Integrin Alpha7 Molecule

...rly those that resulted in an abnormally shortened protein product, or truncation, in 16 of 28 prostate cance...rew at a much slower rate. This suggests that this protein is a fairly potent tumor suppressor,' said Dr. Luo. Dr. Luo and his coworkers then investigated th...

Health Drink Blamed for Persistent Penile Erection

...l supplement for people requiring extra energy and protein in a limited volume''. Boost Plus is available in vanilla, chocolate and strawberry. The company is aware of the lawsuit, accepted a spokesperson unwilling to comment on the litigation pending before the courts....

Why We Feel a Sense of Dj Vu

...said. "This paper demonstrates that a particular protein signalling molecule (the NMDA receptor) in a particular network of brain neurons (the dentate granule cells of the hippocampus) is essential for these rapid discrimination processes, hopefully paving the way for therapies targeting learning and behav...

A Novel Target for Type-2 Diabetes Atk2

...hen insulin is present, as it is after a meal, the protein Akt2/PKB adds a phosphate group to its molecular partner PGC-1a. When this happens, PGC-1a cannot activate the genes needed for fat metabolism. The findings suggest that if a drug could induce Akt2/PKB to add the phosphate group (phosphorylation) t...

Scientists Observed Live Cell Migration

...cross the egg chamber. Another discovery is that a protein called Kuzbanian is necessary to help border cells detach from the egg wall and begin their journey. "We used to think that Kuzbanian allowed border cells to squeeze themselves between other cells as they moved," Montell says, "but only now do we u...

Super Fruit Fly may Harbor Hope for Human Longevity

...ture Chemical Biology, the discovery that a single protein can slow down aging holds implications for humans prolonged existence and for treatment of some of the worlds most dreaded diseases. This work is important for two reasons, said study author Richard Roberts, associate professor of chemistry, chemic...

Malaria Parasite can Cause Severe Lymphatic Cancer

..., Burkitt's lymphoma, can be initiated by CIDR1, a protein produced by a malaria parasite. The study was c...f the study, researchers analysed whether CIDR1, a protein produced by the malaria parasite could reactivate EBV, by exposing the immune cells of healthy Afric...

Researchers Find New Target to Treat Type 2 Diabetes

...t metabolism control. Researchers found that the protein Akt2/PKB adds a phosphate group to its molecular partner PGC-1a in the presence of insulin after a meal. It results in blocking the activation of the genes by PGC-1a that are required for fat metabolism. Muscle and fat tissue also burn fat stores, ...

1 2 3 4 5 6 7 8 9 10