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Tag: "protein" at medical news

A new century of Alzheimer's disease research

...here. More recent research has shown that the AB42 protein folds in such a way that it creates a pleated-shee...hey had been examining blood serum for evidence of protein “markers” that could help predict which people would develop the disease over time. One marker is AB...

Researchers Discover How Cancer Evades the Immune System

... cells, and over-production of B7-H4, a gene whose protein product inhibits immune activation. The human colorectal cancers, however, showed variations in their immune signatures, which researchers saw as an indication of the need to understand the signature for each patient's individual cancer. "I see ...

Structure of TB Enzyme Points the Way to New Drugs: Study

...ase. The Swiss team first identified the enzyme, protein kinase G (PknG), as a promising drug target back in 2004. At the time, they said that the protein is the secret weapon that enables the TB bug, Mycobacterium tuberculosis, to avoid being hunted down...

Blood Protein may Hold Key to Why Healthy People Get Heart Attacks

Boffins have identified a blood protein myeloperoxidase (MPO) secreted by white blood cells, that both signals inflammation and releases a bleach-like substance that damages the cardiovascular system, which might be a clue to why apparently healthy persons could be at high risk of heart a...

Prions Prevent Alzheimers Disease

...rain cells reduce the formation of beta-amyloid, a protein that binds with others to build plaques in the bra... the effect of high and low levels of normal prion protein on the successful formation of beta amyloid, the source of Alzheimers plaques. They found that beta ...

Alternative Splicing in Neuronal Development

...ternative splicing. Polypyrimidine-tract binding protein (PTB) is a well-known inhibitor of alternative splicing in various cell types. A neuronal version of PTB - called nPTB - is expressed solely in nerve cells, but its function has remained elusive. Dr. Black and colleagues now show that a switch in e...

Gene Variation Increases the Risk of Lung Cancer

... researchers said. According to Engels, the IL1B protein is an integral part of the chemical cascade by which cell signals moderate the response to inflammation. Variations in the gene may lead to greater expression of the protein, which is more likely to turn on the cascade and sustain the damaging effect...

Variation in Genes Related to Inflammation Increase Lung Cancer Risk

...ion process. The researchers noted that the IL1B protein was an integral part of the chemical cascade by which cell signals moderate the response to inflammation. Variations in the gene might lead to greater expression of the protein, which is more likely to turn on the cascade and sustain the damaging e...

New Antidotes may Harbour Treatments for Deadliest Poisons

...work and endoplasmic reticulum before interrupting protein synthesis. A team of researchers led by Jose Saenz screened 14,400 small molecules for compounds that could halt this journey without disrupting normal cell function. According to New Scientist magazine, the researchers' work led to the identif...

Common Environmental Chemicals Hamper Ovary Development in Foetus

...ses in the treatment group had fewer eggs and many protein abnormalities. "We examined the ovaries from the...e fields contained fewer eggs and also a number of protein abnormalities. These differences could have implications for problems such as cancer in later life,"...

Great Lakes Fish in Canada Heavily Polluted

... report. Although fish are a food source high in protein and many health experts recommend regular consumption of them, the report said it did not want to discourage people from eating fish but wanted to highlight the need for continuing action to reduce discharges of harmful chemicals into the water. Fi...

Lab Tests Throw Up New Path for Parkinson's

Finnish doctors say they have identified a new protein that, in rats, rescues brain cells whose death causes Parkinson's disease , the tragic degenerative disorder of the central nervous system. The new molecule, called conserved dopamine neurotrophic factor (CDNF), prevents the degeneration of cells t...

New Oncogene for Brain Cancer

...first time that insulin-like growth factor binding protein 2 (IGFBP2) connects with two other proteins to fue...aused by a treatment that targeted the gene or its protein product. Fuller and Zhang first associated overexpression of the gene with brain cancer in 1999. O...

Fibrinogen may Inhibit Spinal Cord Regeneration

Fibrinogen, a blood-clotting protein found in circulating blood, has been found to inhi...hen blood leaks into the nervous system, the blood protein contributes to the neurons inability to repair themselves. The findings, which show the molecular ...

New Blood Vessels can Be Created from Bone Marrow Stem Cells: Study

...f study, the researchers used a fluorescent marker protein and a tissue-specific promoter for alpha-actin, a protein found in muscles that is responsible for their ability to contract and relax, to develop the new met...

New Insights into Prion Propogation

...er's yeast, while Saupe's research looked at prion protein in another fungus. A key difference between the ...ids glutamine and asparagine in the regions of the protein used to transform them into a prion. In contrast, the fungal prion lacks a rich supply of these amin...

Exercise Reduces Inflammation

...fter exercise on circulating levels of C-reactive protein (CRP). Parasympathetic tone and its inverse function sympathetic tone are components of the autonomic nervous system. CRP, which is secreted by the liver, circulates in the bloodstream and is a biomarker for inflammation in the body. The sympathe...

Genetic Factors Behind Mosquitoes Resistance to Malaria Identified

...istant to malaria. The researchers say that TEP1 protein in the mosquitos immune system is the key to their...l parasite manifest mainly in a region of the TEP1 protein called the warhead, the portion that grabs the parasite. TEP1 is a scout that finds the enemy, in...

Protein That Absorbs Lipids may Provide Future Weight-loss Strategies

...ne in St. Louis has led to the identification of a protein that absorbs lipids in the upper part of the inte...iversity School of Medicine, first identified CD36 protein that facilitates the uptake of fatty acids. The protein is located on the surface of cells and distr...

Liver Cancer More Prevalent in Males

Production of a protein that promotes inflammation appears to be linked to...discovery that female mice produce far less of the protein called interleukin-6 (IL-6) in response to liver injury than males do, and that production of this p...

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