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Tag: "proteasome" at medical news

Successful Islet Cell Transplant in Mice With Type 1 Diabetes

...atients to see if they are suitable candidates for proteasome inhibitors, a promising class of anti-cancer drugs...n cancer patients whose tumors do not produce p53, proteasome inhibitors might be ineffective. This patient group could be spared unnecessary treatment with possi...

Philadelphia Researchers Found A Novel Way To Fight Several Kind of Cancers

... both surprised and lucky," he says. "Velcade is a proteasome inhibitor, but it also induces the lytic cycle thereby activating the TK in the Epstein-Barr virus. Once the TK is activated, we can image the tumors." To test their findings, the researchers used mice carrying human Burkitt's lymphoma, a cancer o...

Tailor-made Cancer Treatment for Multiple Myeloma Patients Offered by Mayo Clinic

...e first approved in a new class of agents known as proteasome inhibitors. Proteasomes are large protein groups i...break down other proteins. Agents that inhibit the proteasome cause a buildup of proteins that affect many signaling cascades (various necessary biological proces...

'Mix and match' of proteins may have a significant role in immunity

...ieces, leads to the formation of peptides. "The proteasome can splice peptides together," says Warren. “Every once in a while, new peptide bonds will be created, not just destroyed. It isn't clear why this happens, or what the newly spliced peptides do. But as the molecules end up on the cell's surface, they...

Cellular System Causing Destruction Of Faulty Proteins In Cystic Fibrosis Identified

...asome. This trash system is known as the ubiquitin proteasome pathway. "We've identified the trash collectors that recognize misfolded proteins, decide if they might be toxic to the cell and mark them with ubiquitin. The ubiquitinated proteins, including faulty CFTR, are then degraded or shredded by the prot...

Study Would Pave Way for the Development of New Drugs That Targets TB Proteasome

...the structure and biochemistry of the TB bacterial proteasome from those found in human cells. This would greatl... human cell survival. So any drug targeting the TB proteasome would have to be extremely specific. Hence studies should be very specific in identifying the unique...

Latest drug shows promise in multiple myeloma

...r later. Bortezomib is a new kind of drug called a proteasome inhibitor. It acts on tiny structures called proteasomes within cells and so stops myeloma cells from multiplying....

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(Date:7/10/2014)... Estonian-born Katerina Alba,s research at the University of Huddersfield ... the most popular emulsion-based food products such as ... is starting to gain an international profile for her ... and food science at the University and now she ... with her supervisor, Dr Vassilis Kontogiorgos, she is investigating ...
(Date:7/10/2014)... A neuroscientist at Rutgers University-Newark says the human brain ... a finding that could provide a better understanding ... conditions that afflict an estimated 13.6 million Americans. , ... , Michael Cole, an assistant professor at the Center ... brain architecture of a person at rest is basically ...
(Date:7/10/2014)... sarcomas research group at the Bellvitge Biomedical Research Institute ... been tested in 19 patients a new therapeutic combination ... indicate that the new treatment could stabilize the growth ... the British Journal of Cancer ., Sarcomas ... complex since there are several subtypes. It can affect ...
(Date:7/10/2014)... 10, 2014) Men who experience hot flashes are ... find relief from their silent suffering if they ... findings from a Baylor University case study., After seven ... had uncontrolled hot flashes following prostate cancer surgery showed ... also an impressive improvement in sleep quality, according to ...
(Date:7/9/2014)... that sudden, acute episodes of low back pain are ... air pressure, wind direction and precipitation. Findings published in ... the American College of Rheumatology (ACR), indicate that the ... wind speed or wind gusts, but was not clinically ... (WHO) nearly everyone experiences low back pain at some ...
Breaking Medicine News(10 mins):Health News:World interest in research work on the benefits of the Okra plant 2Health News:Working to loosen the grip of severe mental illness 2Health News:New therapeutic combination to slow resistant sarcomas 2Health News:Men's hot flashes: Hypnotic relaxation may ease the discomfort men don't talk about 2Health News:Men's hot flashes: Hypnotic relaxation may ease the discomfort men don't talk about 3Health News:Men's hot flashes: Hypnotic relaxation may ease the discomfort men don't talk about 4Health News:Low back pain? Don't blame the weather 2
(Date:7/10/2014)... business incubator, received a $1.4 million federal grant to ... staunch bleeding during brain surgery. , Surgeons can spray ... bio-polymer solutions in the gel will cohere and control ... The gel can shorten an intracranial surgery by 30- ... the patient,s skull to be open and less anesthesia, ...
(Date:7/10/2014)... State University have developed a small, portable and ... over the world better understand the radiation around them, ... poses a health risk. , The device was developed ... incident in Fukushima, Japan, in 2011, when many regional ... being exposed to and whether their homes, food, environment ...
(Date:7/10/2014)... Cancer Research Centre (CNIO) Macromolecular Crystallography Group has ... called BuD to DNA in order to redirect ... researcher who led the study, says the discovery: ... instructions contained in the genome to treat genetic ... is published in the journal Acta Crystallographica, ...
Breaking Biology News(10 mins):A start-up at NJIT develops bleeding-control gel for brain surgery 2Sophisticated radiation detector designed for broad public use 2Sophisticated radiation detector designed for broad public use 3CNIO scientists develop technology to redirect proteins towards specific areas of the genome 2
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