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Tag: "protease" at medical news

African HIV strains more resistant to anti HIV drugs

... of the National Academy of Sciences.Comparing the protease inhibitor to a key and the protease to a lock, Dr. Freire said when there are new strains of the virus, the key will not fit the lock an...

Drugs to stop burgeon of HIV

...– reverse transcriptase inhibitors such as AZT and protease inhibitors. These work by targeting the reproduction of the virus within the host cell."The problem is HIV can mutate to escape the drugs you are using to treat it," said Professor Gage. "If this occurs, the drug will kill off all non-mutated cells l...

More about HIV

...has been replaced by more powerful treatments like protease inhibitors, but it's typical for powerful drugs to have even greater side effects. And with greater side effects comes greater stress reactions and the risk of illness and disease not even related to the infection.Currently, there are two problems w...

Garlic Supplements Impede HIV Therapy

...of the saquinavir, one of a class of drugs called protease inhibitors that are effective at slowing the progression of HIV infection. In the presence of garlic supplements, blood concentrations of saquinavir decreased by about 50 percent. For the study, nine healthy, HIV-negative volunteers received saquina...

AIDS drugs linked to heart attack risk

...re medicines, including a category of drugs called protease inhibitors that are a key ingredient of the pill combinations.// New research raises the possibility that life saving AIDS drugs may also increase the risk of heart trouble, though experts say the medicines' benefits outweigh any danger. Researchers ...

Common Cold Remedy May Treat SARS

...irus. Since viruses for SARS and common cold use protease to reproduce, SARS drug would fight the disease by... blocking the protease. Researchers hope to find a protease inhibitor against SARS soon. However developing a safe drug may be taking time. Meanwhile, researche...

Cure For Persistent Oral Fungal Problem May Be Possible

...troy them. This may be achieved by synthesizing a protease inhibitor cocktail that may inhibit the enzymes that kill the peptides. This cocktail thus may be able to increase the ability of the peptides to treat potential oral infections up to double their original power. One peptide called MUC7 12-mer, whi...

New Combination Therapy Option for HIV Patients

A HIV protease inhibitor Aptivus ( tipranavir ) , has been recently approved by the Food and Drug Administration // . The capsules are to be given in combination with ritonavir for treatment of HIV-1 infected adults. This is the second drug approved for patients w...

Prostratin- Drug to eradicate HIV

...sing performance, will eradicate HIV-disease. When protease inhibitors were given to patients, researchers claimed that HIV will be 'eradicated'....

Oral Sex may carry AIDS related Cancer Virus

...troduction of powerful drug "cocktails" containing protease inhibitors....

Roche offers HIV drug expertise to poor nations

...IV/AIDS population in the world. Saquinavir is a protease inhibitor, one of a class of drugs that work by bl...-line products. Roche said it would make its HIV protease inhibitors Invirase and Viracept available at no-profit prices for direct supplies from Roche Basel ...

TMC 114 and 125 experimental drugs to be tested on four HIV patients

...re found resistant to nevirapine. TMC 114 is a HIV protease inhibitor, which is found to be an analogue to TMC 126 and is found to be effective in reducing HIV virus burden. These clinical trials are conducted in these four patients who had shown resistance to most of the anti-retroviral drugs. These exper...

Patients with HIV-1 can predict plasma lipids level based on race

...etic variants of lipoproteins apoC-III/apoA-I, and protease inhibitors (a class of drugs used against HIV) aff...cess to highly active antiretroviral therapy. Some protease inhibitors have been associated with elevated levels of cholesterol, triglyceride, and low high-dens...

Need For Low Cost, Heat Stable HIV Drug in Developing Countries

...vir belongs to a class of compounds referred to as protease inhibitors. The latest version of the drug that is heat stable was launched for sale in the US in November 2005. The drug does not require refrigeration for storage, making it ideal for use in hot climates, prevalent in most developing countries. T...

New Group Of Drugs For HIV Treatment

...rom copying its DNAinto the human genome,while the protease inhibitorspreventthe production of new viral particles. A recent market report put forth by Datamonitor suggests that by 2012, global sales could be just under $12 billion (€9.2 billion), which approximately double the value recorded for 2003 ($...

Finally, The First Ever Treatment for Drug-Resistant HIV

...ne of the most common treatments existing today, a protease inhibitor. Protease is an enzyme necessary for HIV to reproduce properly. A protease inhibitor binds to protease, making it unusable by the virus. Without the use of protease, HIV is in...

Research Leads to First Treatment for Drug-Resistant HIV

...ne of the most common treatments existing today, a protease inhibitor. Protease is an enzyme necessary for HIV to reproduce properly. A protease inhibitor binds to protease, making it unusable by the virus. Without the use of protease, HIV is in...

Study Shows Promise For Simplified Treatment of HIV Infection

...minary study indicates that using a single boosted protease inhibitor instead of the standard regimen of 3 dru...ssion for 48 weeks or longer receiving their first protease inhibitor (PI)–based regimen. Participants switched PIs to atazanavir-ritonavir at entry and discont...

Study Compares First-Line Drug Therapies For Treating HIV

...than the three-drug combination of two NRTIs and a protease inhibitor called lopinavir/ritonavir. Moreover, a ...se a general belief that combining an NNRTI with a protease inhibitor could result in resistance to two important classes of drugs. But earlier studies with oth...

Dr. Scott Hammer Authors Two New Guidelines for HIV Treatment

...en in patients with the drug-resistant virus using protease inhibitors or the drug enfuvitide. "These guidelines for treating HIV patients with antiretroviral therapy (ART) are important for clinicians worldwide given the rapid evolution of knowledge, the complexity of the field, and the varied clinical sit...

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