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Tag: "promyelocytic" at medical news

Citrinin, a fungal toxin, induces apoptosis via mitochondrial pathway

...hrough the mitochondria-dependent pathway in human promyelocytic leukemia cells (HL-60) and the process is not dire...h cellular oxidative stress. For the study, human promyelocytic leukemia (HL-60) cells were chosen to identify the apoptotic process induced by CTN. Morphological e...

Arsenic Compound Effective in Treating Rare Leukemia

...survival. Patients all had newly-diagnosed acute promyelocytic leukemia, or APL, and participated in a multi-year national phase III clinical study. Twenty eight patients from NSUH and LIJ enrolled in the clinical trials, the largest number of participants from any facility in the New York metropolitan area – an...

Leukemia Drug Turns Mini-Molecules Up, Cancer Genes Down

...shows that a form of vitamin A used to treat acute promyelocytic leukemia induces changes in an unusual class of sm...r Hospital and Solove Research Institute. Acute promyelocytic leukemia occurs when cells that give rise to a form of white blood cell become stuck at an immature ...

Arsenic Poison can Make Longer Life of Leukemia Patients

...rioxide in standard first-line treatment" of acute promyelocytic leukemia (APL) a rare form of acute myeloid leukem...e by Cephalon, Inc and marketed as Trisenox. Acute promyelocytic leukemia represents about 10 percent of cases of acute myeloid leukemia, and hits about 1,500 people...

Insights into Acute Promyelocytic Leukemia

...ecific mechanisms involved in development of acute promyelocytic leukemia (APL) and identifies promising new avenues to develop treatments for some of its variant forms. Results from two new studies provide key mechanistic insights into the complex molecular events that cause a deadly type of leukemia.APL is a c...

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