Surface Logix Commences Phase 2a Clinical Trial of SLx-2101 in Raynaud's Disease
...aking it the first PDE-5 inhibitor to confirm such prolonged duration of activity using an objective measure. Phase 1 studies of SLx-2101 in healthy male volunteers demonstrated its favorable safety, tolerability, pharmacokinetics and pharmacodynamic activity. Additionally, in preclinical animal models, the ...Should Menstrual Suppression Be a Lifestyle Choice?
...d women are more likely to skip periods. Even if prolonged monthly menstruation were unnatural and unhealthy, this would not prove that suppressing menstruation is better, she adds. Menstrual suppression itself is unnatural; a drug chronically overrides the physiological changes associated with the menstrual...Insulin Therapy Shown to Treat Early Experimental Diabetic Retinopathy
...to provide low levels of insulin to the retina for prolonged periods. The hydrogels were engineered to be thermoresponsive and hydrolytically degradable, and their pharmacokinetic and pharmacodynamic properties were studied in vitro and in vivo using R28 cells in culture and SD rats respectively. Lead resear...Aspirin can Prevent Bowel Cancer, Says UK Study
... on a daily basis. "Aspirin at this dose over a prolonged period of time could lead to potentially serious side effects in a few people." According to another recent study, women who take aspirin in low or moderate doses reduce their risk of dying from any cause, particularly heart disease. Researchers ...Researchers Identify Immune Dysfunction in Melanoma Patients
..., in which some doctors have treated patients with prolonged exposure to interferon, sometimes helps. "Doctors ...anoma patients for interferon response and provide prolonged interferon treatment for only those patients whose immune cells have defects in that pathway. That m...Antibiotics Highly Effective for Treating Lyme Disease
...se. However, there is no compelling evidence that prolonged treatment with antibiotics has any benefit in treating symptoms that persist following standard therapy. The guideline is published May 23, 2007, in the online edition of Neurology, the scientific journal of the American Academy of Neurology. Lyme...Breast Cancer Patients Follow-up Devalued
...ase treatment plans which ensure low mortality and prolonged disease-free survival. A flexible programme that both encourages patient choice and develops primary care cancer infrastructure is urgently needed. A national audit of follow-up care could ensure that the wide variety of locally agreed models of comm...Hearing Loss Becoming an Epidemic in Canada
...tening to any sound at 85 decibels or higher for a prolonged period of time can cause permanent damage to hearing. The maximum safe exposure time to 120 decibels is eight seconds. The problem is there is a raft of activities in our everyday lives that exceed those noise levels. For example, an average conver...FDA: New Drug for Advance Kidney Cancer
...roved based on a study that showed use of the drug prolonged survival of patients with renal cell carcinoma. The drug is an enzyme inhibitor, a protein that regulates cell production, cell growth and cell survival. 'We have made significant advances in the battle against kidney cancer,' said Steven Galson, M......e therapeutic dose levels of the immunotherapy had prolonged disease-free survival for a period of at least eig... lymph nodes. In addition, the three patients with prolonged disease-free survival -- but not the five who progressed and died -- showed evidence of treatment-as...Effects of 'starvation Hormone'-Newly Identified in Low-carb Diets
...to the liver when carbohydrates are scarce. During prolonged fasts, ketone bodies can provide nearly half of baseline energy requirements and up to 70% of the energy required by the brain.Maratos-Fliers team examined changes in gene activity occurring in mice fed a high-fat, low-carb diet for 30 days. Their co...WHO Cautions Against Spread of Drug-resistant Tuberculosis.
...cteria through air. Anyone can become infected,but prolonged exposure is usually required. ``About 30,000 out of the 420,000 cases, are extremely drug resistant.This means they are resistant to first line and a number of secondline drugs,'' according to a recent interview of Dr Mario CRaviglione, director of...Super Fruit Fly may Harbor Hope for Human Longevity
... can slow down aging holds implications for humans prolonged existence and for treatment of some of the worlds most dreaded diseases. This work is important for two reasons, said study author Richard Roberts, associate professor of chemistry, chemical engineering and biology at the University of Southern Cal...Overuse of Popular Console can Cause 'Wiiitis' in Gamers
...escribing the cramping of the right hand caused by prolonged use of traditional video game controllers. Though Bonis suffered a sore shoulder, he warned that the flexibility of the could cause injuries to other parts of the body. "Future games could involve different and unexpected groups of muscles," he war...Taiwan Researchers Claim Cancer Therapy Alternative
...ce treated with the new compound had significantly prolonged survival time compared to those treated with a-Galcer, the research institute said in a statement. The Japanese research did not go beyond a phase I trial because while A-Galcer was found to enhance immunity by helping some proteins, it also damaged ...Should Menstrual Suppression Be a Lifestyle Choice?
...d women are more likely to skip periods. Even if prolonged monthly menstruation were unnatural and unhealthy, this would not prove that suppressing menstruation is better, she adds. Menstrual suppression itself is unnatural; a drug chronically overrides the physiological changes associated with the menstrual...Food Preparation may Play a Bigger Role in Chronic Disease
...en in diabetic patients may suggest that early and prolonged exposure to these substances in the diet could accelerate the onset of diseases. Dr. Vlassara notes that the availability and consumption of AGE-rich foods is high and correlates with rising rates of diabetes and heart disease. "Excessive intake o...Exhaustive Study to Expand the Efficacy of Drug L-dopa for Parkinson's
... helps in reviving cellular communication//. After prolonged use of the drug, many patients may experience motor complications and a reduced response to the drug. Parkinson's disease is a slow process of destruction of brain cells which produce dopamine. As dopamine levels fall, the symptoms of Parkinson’s s...A Single High Fat Meal Could Boost Blood Pressures
...the basis for her honors thesis. Exaggerated or prolonged responses to stress are thought to predict the dev... cases have no known cause. And he speculates that prolonged and frequent exposure to fast food meals could provide an explanation for many of these. He said f...LCT Reports Major Step for Islet Transplantation in Diabetes Patient
...significant reduction in insulin requirements, and prolonged insulin independence in some individual animals. Source-Eurekalrt SRM...