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Tag: "proliferate" at medical news

New Drug ALT-711 decreases blood vessel stiffness

...ural flexibility of collagen strands. They tend to proliferate with age. Crosslinks appear to toughen tissues and may contribute to some of the deterioration associated with aging and diabetes, such as elevated systolic blood pressure, stiff arteries, and impaired kidney function. The ability to reduce vascula...

Artificial lenses- Boon to cataract patients

...n Atlanta. But cells left behind after surgery can proliferate and cause the lens capsule to stiffen, he says. For variable focus lenses, this could be a problem. If such trails are successful, they add, however, some patients might not need to wear glasses at all - unlike most elderly people, who gradually los...

Understanding Chronic Infections May Help in Developing Therapeutic Vaccines

... proliferate, or expand in number. This failure to proliferate seemed to correlate with a high viral load, which suggests several directions researchers might pursue in improving response to therapeutic vaccines. "The ongoing stimulus to the immune system that occurs in chronic infection seems to prevent the i...

Therapeutic cloning by regenerating stem cells from heart muscles

...ing to growth of 8,000 separate cells, which could proliferate individually. After growth of these cells in cell line, they developed into different progenitor cells, which could differentiate into heart muscles, blood vessels and neurons. The effect of these cells was confirmed by injecting the stem cells into ...

Cancer Cells Trigger Supporting Cells to Turn Cancerous

...lasts, which are connective tissue cells, began to proliferate rapidly. Eventually these fibroblasts lost the protective action of the tumor suppressor, p53. This meant that the cells continued to merrily divide thereby evolving as cancer cells. "This occurred in 100 percent of the animals studied. It's a strong...

Epstein - Barr virus Protein Implicated in Blood Cancer

...In the absence of this control, cells can begin to proliferate very rapidly and become transformed in cancer cells. The researchers have published their findings in the Proceedings of the National Academy of Sciences. Epstein-Barr virus is already implicated in diseases such as AIDS, Burkitt's lymphoma, Hodgkin'...

Genetic mystery behind muscle development unraveled.

...study are instrumental in determining if myoblasts proliferate or differentiate. The research showed that increas...sing the amount of miR-133 caused the myoblasts to proliferate even more, but prevented them from undergoing differentiation. Similar experiments carried out in ...

UK Computer Grid In Bird Flu Fight

...l neuraminidase, an enzyme that helps the virus to proliferate and infect more cells. As this protein is known to evolve into variants if it comes under drug stress, drug resistance becomes a potential concern in case of an influenza pandemic. The challenge of the drug discovery application is to identify thos...

Western Region Tops in Indian Biotech Growth

...ffordable drug development and bio-partnering will proliferate between US/European and Indian firms. "Venture capital will influence an India-China strategy for investor companies; US/Europe will continue to lead the way in discovery research. Asia will provide leading hubs for clinical development and stem ce...

Suitable Culturing Medium, essential for Stem Cell Development

... involved in the research. ‘Stem cells continue to proliferate because they are in a specialized 'niche' that nurtures them and keeps them dividing. Previous studies have shown that factors in the niche are important for stem cell proliferation. Less studied are the means by which these cells are directed to bec...

Scientists Isolate Leukemia Stem Cells in Mouse Model

...sues of the bone marrow in which white blood cells proliferate abnormally, with life-threatening effects. About 35,000 diagnoses of all types of leukemia will be made in 2006, according to the American Cancer Society, with about 22,280 deaths. Some forms of leukemia have a high rate of cure. In other forms, chem...

Center Launches New International Stem Cell Research Institute

...sue burns. In contrast, embryonic stem cells can proliferate indefinitely into all types of cells and are easy to grow and study. By conducting stem cell research, scientists hope to find new treatments for Parkinson’s, Alzheimer’s, cancer, diabetes, multiple sclerosis, spinal cord injuries and other disease...

Britain’s cancer initiatives leap forward with a miracle dru

...pping an important enzyme that causes the cells to proliferate rapidly, as is the case in some cancers. Further Sutent ensures that tumors run dry of nutrients, thus curbing its growth and development. This is perhaps the first drug of its kind that comprises a dual action. Paul Nathan, a consultant oncologist...

CD86 Found On B Cells Boosts Immune Response

...ell releases a substance that causes the B cell to proliferate and churn out antibodies against the antigen. But there was no indication that the interaction between the CD86 protein and a T cell had any influence on the B cell itself. Earlier work by Sanders and her laboratory, however, strongly suggest the CD8...

Deficient 'Scout Cells' Causes Cancer in Transplant Patients

...cout cells alert the memory T cells, which rapidly proliferate and hunt down and kill any cells that contain growing virus or have become cancerous. ,br."If memory T cells are re-stimulated properly, they can kill the cancerous cells before PTLD develops," VanBuskirk says. "But if that re-stimulation is weak or ...

Gene May Regulate Cellular Aging

...ole of p16INK4a in hematopoietic stem cells, which proliferate continuously during the adult lifespan and produce massive amounts of new blood cells on an hourly basis. Their results suggest that p16INK4a is the molecular basis for an old-age 'signal' previously observed in blood stem cells. The Harvard study al...

Why Don’t All Moles Progress to Melanoma

...are held in check – they don’t die, but they don’t proliferate either,” Soengas explains. “In the case of moles, melanocytes can stay this way for 20 to 40 years or even your whole life. For most of us, just holding cells in an arrested state is sufficient to prevent the development of cancer. That’s why so many...

New Tool for Understanding Estrogen-Fueled Breast Cancer

...lls have an unusually large number of ERs, so they proliferate rapidly in the presence of estrogen. Drugs that block the ER, such as tamoxifen and fulvestrant, are often able to stop or slow the growth of these estrogen-driven tumors. "For the most part, the sequence of steps between the activation of the estr...

Non-Steroidal Anti-Inflammatory Drugs Can Cause Liver Damages

...re of the abnormal alpha-1-ATZ protein but also to proliferate or multiply faster than usual -- a hallmark of liver response to injury. People who have alpha-1-AT deficiency vary widely in the severity of liver injury: some patients never have liver problems while others will require a liver transplant before ...

The Immune System May Be Altered By Certain Chemicals

...KA also inhibited the ability of type 2 T cells to proliferate and survive. Penn said this finding could influence future drug development, because new beta agonists that are more effective in activating PKA may prove useful. Source-Eurekalert SRI...

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