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Tag: "profiling" at medical news

Bioengineering production strains - Microbia develops new methods

...and then utilized these arrays for transcriptional profiling of strains engineered to produce varying levels of lovastatin-a drug used widely to treat high cholesterol. By integrating transcriptional and metabolite data, the authors elucidated the key genetic components and critical regulatory nodes affecting ...

New Race –Specific drug

...e is a powerful lobby which is in favour of racial profiling when it comes to drug development, backed by evidence that suggests a degree of truth in the ethnicity theory. The reasons for the difference inresponse to a drug are unclear although it is thought that genes play a major role. Type-2 diabetes is m...

Nutrient Profiling System Launched By Food Officials in UK

...d, regulators could look towards the UK's nutrient profiling system in the near future say reports. Medindia on diet and nutrition: Medindia Calorie Calculator helps in calculating Daily Average Calorie needs of individuals. This calculator would be of immense use to those intending to shed weight. Calor...

Hip Replacement Can Now Be Performed On Virtual Patients

...veral techniques involving virtual reality, tissue profiling and stereoscopic vision have been culminated to create virtual patients that mimic the tissue of real patients. After the virtual surgery, doctors can even get a feedback regarding the likely success or failure of the operation. These devices create ...

Proteomic Profiling Can Detect Preterm Birth Risk

...gnant women are concerned can be diagnosed through profiling particular proteins // for inflammation in amniotic fluid. The chances of a premature birth taking place can also be predicted through this process, according to the researchers. This will be presented on 2 February 2006, at the 26th Annual Socie...

Ultimate Destination of anti-depressant, Prozac

...eir existence, have been a mystery until now. By profiling the telltale marker proteins produced by different kinds of cells in the brains of adult mice, the researchers first defined discrete steps in the complex process, called neurogenesis, that converts unspecialized stem cells into mature, specialized n...

Breast Cancer Mortality Rate is Higher Among Black Women

...xpression patterns, which, in turn, enable genomic profiling of tumor cells. UNC School of Medicine study co-author Dr. Charles M. Perou, assistant professor of genetics, pathology & laboratory medicine, and a Lineberger member, is a pioneer in microarray technology. 'Gene expression analysis using DNA micro...

Cell Survival Depends on Chromosome Integrity

...ogies, mass spectrometry technologies, single-cell profiling and other novel methods to detect, quantify and monitor lysine modifications on DNA-coiling histones. Histone modifications are critical for many biological processes, such as epigenetic control of gene expression, which itself dictates the expressio...

Novel Approach Assists in Locating Leads for Drug Discovery

...ning will aid better precision and accuracy in the profiling of compounds in chemical libraries, which will enh...demonstrates the feasibility of a new paradigm for profiling every compound in large collections of chemicals. Traditional high-throughput screening measures the...

Novel test for diagnosis of breast cancer

...om University Hospital Basel found gene expression profiling of needle biopsy samples gave an accurate picture ...College School of Medicine, said: "Gene expression profiling tells you the likely natural history of the disease - whether it is going to be aggressive or not - ...

Genetics to bring about Medical Breakthroughs

...akthroughs of the future.According to them//, gene profiling will transform the way patients are treated, within a period of ten years. "This new technology means consumers will have little choice but to take preventive action when faced with proof their lives might be at risk, " says John Shine, the executi...

Age of Medical Miracles has come upon us

...heal brain injuries. Breakthroughs, such as gene profiling to detect disease risk are expected to become available within a decade while some such as the growth of new organs through stem cell research could take longer but are still likely in the foreseeable future. One of the scientists, Professor Graeme...

Profiling of Cancer Genes May Lead to Earlier Detection Human Cancers

...t that it may be possible to develop a methylation profiling platform that could be used to screen patients for common solid tumors, while at the same time identify what type of tumor the patient may have,” Dr. Shames said. The study also illustrates that some of the basic processes that underlie the develo...

Accuracy of Gene Expression Test for Heart Transplant Patients Confirmed

...y) study reported the utility of a gene expression profiling (GEP) test, called AlloMap? molecular expression test, which led to the test’s commercial availability in January 2005. Currently 40 transplant centers in the U.S. offer the test. 'GEP testing is not only less invasive and less risky than biopsy, it...

New Test Predicts CLL’s Sensitivity to Experimental Drug

...etai said work is under way to make the laboratory profiling operation more automated, looking toward a time when it could be used on a routine basis to assess the vulnerability of patients' cancers to compounds that antagonize BCL-2 or related anti-death proteins. "This is a totally new class of drugs and h...

FDA Clears Breast Cancer Specific Molecular Prognostic Test

...pes of data that should support claims for genetic profiling for breast cancer prognosis. According to the American Cancer Society, an estimated 178,480 new cases of invasive breast cancer will be diagnosed among women in the United States this year and over 40,000 women are expected to die from the disease....

Genetic Tests to Reveal ‘substance Abuse’ Tendencis

...te of Systems Biology in Seattle. "Transcription profiling involves looking at all the genes -- nearly 30,000 of them -- at one time. We label all the expressed genes by fluorescent tags, and changes in fluorescence intensity are used to identify differential gene expression," Madan explained. "We can see ...

Gene Test Shown to Measure Heart Function After Transplant

...planted heart is performing.// The gene expression profiling (GEP) test, known as the Allomap test, is currently used to detect the absence of heart transplant rejection instead of routine invasive heart muscle biopsies, but has now been shown to correlate with oxygen saturation levels, the pressure in the hea...

Drink, Binge and the Genetic Link

...arkers of familial alcohol-dependence. Genetic profiling through technologies like microarrays , also known as gene chips, is in increasing demand. Attempts are being made to shape treatment protocols by studying the causative genetic variants. Prevention and treatment of smoking and other abusive s...

New Genetic Clue to Type 1 Diabetes

...KIAA0350 were spotted as risk factors in a genetic profiling of 563 patients with Type 1 diabetes, which were compared to 1,146 healthy people, says the study, published online Sunday by Nature. Type 1 diabetes occurs when the immune system destroys cells in the pancreas that produce insulin, the hormone tha...

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