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Tag: "preclinical" at medical news

Antioxidant Molecule Could Help Minimize Stroke-Linked Brain Damage

...rofessor of neurology/neuroscience and director of preclinical stroke modeling at the Burke Medical Research Institute in White Plains, N.Y. The new study suggests that SS31 works by inhibiting the activity of CD36, a "scavenger" receptor that Dr. Cho and her colleagues in the Department of Neurology/Neurobiol...

A New Pain Killer With Less Side Effects

...sthesia Division has been at the forefront of such preclinical research." Since appointment in 1991 as a lecturer Professor Lambert has been working on opioids and opioid receptors with particular emphasis on understanding receptor function and the design and evaluation of new drugs to target these receptors. ...

Four-way Dengue Vaccine a 'success', Say Scientists

...d that the vaccine had also demonstrated safety in preclinical toxicology studies. Dong told SciDev,Net that a further study on non-human primates has been conducted and will soon be submitted to a scientific journal for publication by colleagues at the US-based Naval Medical Research Center. Prida Malasit o...

Drug Companies Should Not Have a Monopoly Over Clinical Trial Data

...e rights to commercial companies over clinical and preclinical trial data—could jeopardize efforts to create gene... medicine, safety and efficacy are established via preclinical and clinical trials; hence submission of the trial data is an important prerequisite for registratio...

Natural Brain Substance Linked to Parkinson's Symptoms

...studies to prove, with the possibility of years of preclinical research to even reach the human testing stage. Independent experts said it was an intriguing new lead for a condition that afflicts 1.5 million people in the United States. "This is an extremely intriguing finding," said Joan Samuelson, president ...

Novavax Says Bird Flu Vaccines Effective

...its virus-like particle vaccines were effective in preclinical studies in protecting// against different strains of the bird flu virus, and its shares surged in after-hours trading. The studies involved two of Novavax's H5N1 influenza virus-like particle, or VLP vaccines, one targeting the Indonesia strain of ...

Oral Flu Vaccine On The Horizon In Russia

...nza Research Institute (RAMS) recently completed a preclinical study on intranasal formulation, with encouraging results. Clinical studies are due to start this autumn, and the vaccine will follow in the footsteps of a rival intranasal flu vaccine, MedImmune's FluMist, which is already on sale in the USA. The...

Researchers Find Stem-cell Therapy Effective in Targeting Metastatic Cancer

...rostate and breast cancer, and are planning future preclinical trials using those tumors as well. Source-Eurekalert...

Common Virus Enhances Cancer-Fighting Ability of Standard Chemotherapy Drugs

...ncer-killing abilities of existing cancer drugs? A preclinical study presented// at this year’s EORTC-NCI-AACR symposium on Molecular Targets and Cancer Therapeutics, in Prague, Czech Republic concluded that the answer is “yes.” These findings may lead to more effective treatment options for patients suffering f...

"Trojan Horse" Agent Halts Bone Metastasis in Mice

... bone tumors in 50 percent of the mice tested in a preclinical //study, providing early evidence that it could treat, or thwart, growth of tumors in bone, a common destination for a number of cancers when they start to spread. Researchers at The University of Texas M. D. Anderson Cancer Center reported in the ...

Swelling of Prostate Gland Prevented with New drug

... “It’s interesting work, and we are pleased that preclinical testing may translate into real benefits for patients.” Source-Medndia NLA...

Inhibition of Colorectal tumor growth by Grape seed extract

...th Sciences Center in Denver. "The value of this preclinical study is that it shows grape seed extract can atta...ive activity against skin cancer. Their subsequent preclinical work has shown that the extract also retards growth of prostate cancer cells. In this study, Agarw...

New Drug Blocks Influenza, Including Bird Flu Virus

...nfection. The team hopes to move the research into preclinical phase as quickly as possible. Currently, there are a few effective antiviral medications on the market for influenza, but they are beginning to show signs that they are losing their effectiveness, and scientists and health professionals worry that ...

Bacterial Protein Shows Promise in Treating Intestinal Parasites

...e the spectrum of activity of Cry5B as part of its preclinical development as a human therapeutic.” ource-Newswise SRM...

Tiny Sphere Of Nanoparticles Can Fight Cancer

Researchers have found in a preclinical trail, that siRNA packed as a tiny sphere can shrink ovarian cancer.// Researchers from the University of Texas M. D. Anderson Cancer Centre had reported in the August 15th edition of Clinical Cancer Research, that siRNA that are wrapped up in a ti...

Genes Identified To Protect Heart Muscles

...aboratory is actively pursuing the development and preclinical testing of these new gene therapies using sophisticated viral vector systems, which are highly responsive to the pathological conditions of the plaque itself. Although the possibility of using these experimental therapies in the clinical setting is y...

Advance in Program for Development of Non-Intravenous Therapy for Hemophilia

...al for milestone payments for achieving discovery, preclinical and clinical goals as well as royalties in the event of marketing approval. About Hemophilia People with hemophilia do not produce adequate amounts of factor VIII or factor IX protein, which are necessary for blood to effectively clot. If untreated...

Manual vs. Automated Chest Compression After Cardiac Arrest

...ign and implementation strategies may need further preclinical evaluation. The results of this study underscore the complexity of resuscitation from out-of-hospital cardiac arrest. Further work is required to understand the interaction of manual or assisted chest compressions with other aspects of resuscitation...

New Multi-Modal Contrast Agents, A Boon For Medical Imaging

...last? All of those kinds of things are part of the preclinical work, before people can even consider usin it.’ Source: Eurekalert...

New Gene Therapy Treats Diabetic Neuropathy

A preclinical trail carried out to treat diabetic nerve damage h...ds and feet – diabetic neuropathy. The positive preclinical results – reported in the journal Diabetes – are further evidence that the research could lead to a ...

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