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Tag: "poorly" at medical news

Merck's Pain Reliever Arcoxia Rejected by US Federal Advisory Panel

...icials criticized Merck for using what they called poorly designed scientific studies in an attempt to put Arcoxia in the best possible light. Bruce Psaty, director of the cardiovascular health research unit at the University of Washington, says manufacturers can "rig" trials by comparing their drug to on...

Training Health Workers and Better Drug Access Vital to Combat TB in Mozambique

...a need to focus on people living in unsanitary and poorly ventilated conditions, who are more vulnerable to TB. Sampaio also highlighted the need to prevent the development of multi-drug resistant strains of the disease, including extensively drug-resistant TB, which is resistant to the two most potent f...

PSA Not a Good Predictor of Lethal Prostate Cancer

...write. "However, early PSA characteristics perform poorly in distinguishing those who develop a lethal prostate cancer from those at low or no risk of disease progression. Therefore, better decision tools are needed for active monitoring of patients with early disease." In an accompanying editorial, Dipen...

Revised Cholesterol Guidelines Causes Concern Among Medical Community

...ut the long-term effects of statins have been very poorly studied. "Prescribing a drug to a healthy person needlessly puts them at risk for a drug's side effects," says Zickler. In the case of statins, there are two very important side effects, although they are extremely rare: a muscle-wasting condition an...

Stroke Treatment Works Better For Men

...t. While discussing the reasons for women faring poorly after stroke and tPA treatment, Mitchell S. V. Elkind, Associate Professor of Neurology at Columbia University Medical Center said that the blood of women have higher level of substances which will cause clots. He also added that post-menopausal wo...

WHO Urges Higher Priority for Neglected Diseases

...h and development, and health programmes are often poorly implemented. International funds tend to be directed towards childhood immunisation and treatment of HIV/AIDS, malaria and tuberculosis — the three diseases that kill the most people globally. "Other communicable diseases, including leprosy, fila...

Researchers Discover Potential Targets To Reduce Risk Of Stem Cell Transplants

...ny remaining cancer cells to prevent relapse. But, poorly matched donor grafts can be rejected, just as in organ transplants, or cause GvHD. "Currently, suitable donors can only be found for 20 to 30 percent of patients who might be cured by allogeneic transplants," said Kerr. "But by learning which genes c...

Scientists Uncover Cause of Antipsychotic Drug Weight Gain

...chizophrenia and bipolar disorder in people who do poorly on conventional drugs. Mice given clozapine showed quadrupled AMPK activity compared to activity measured pre-drug. The researchers then gave the mice leptin, a hormone that suppresses appetite, and as suspected, saw lowered AMPK levels. Drill...

Long-term Marijuana Smoking Leads to Respiratory Complaints

...l outcomes, the effect of marijuana smoke has been poorly understood,” said Tetrault, ambulatory care fellow at Yale School of Medicine and the Department of Veterans Affairs Connecticut Healthcare System. Tetrault and colleagues systematically reviewed articles from 1966 through 2005 identified from the ...

Man-Made Proteins Could Be More Useful Than Real Ones

... these synthetic a-peptides adopted very little or poorly defined tertiary structure, and no one had yet shown that a a-peptide could self-assemble into the kinds of stable bundles of spiral-shaped helices that are characteristic of natural proteins, Schepartz said. In their studies, Schepartz and collea...

Environmental Toxicants Target Stem Cells

...ases and health problems that have heretofore been poorly understood by the medical community. Noble and his colleagues are pioneers in the field and have been involved in the discovery of several of the progenitor cells that are involved in building the central nervous system. The growing knowledge of t...

Tuberculosis Experts Outline Proposals to Speed Up Drug Development

...large part because existing TB drugs and tests are poorly adapted for use in people with HIV/AIDS. "In TB research, there needs to be a convergence of innovation, incentive, and access," said Dr. Carl Nathan, Rees Pritchett Professor of Microbiology and Chairman of Microbiology and Immunology at Weill Cor...

One in Four Specialist Trainee Doctors 'Very Worried' About Future Job Prospects

...ponses reveal. Eight out of 10 respondents felt poorly prepared to meet the challenge of working as specialist practitioners in the community, and wanted additional training to enable them to work in the new environment. Three out of four felt that this should take the form of a university based degre...

Genetic Tests in the Treatment of Depression Not Yet Useful

...t test for all variations of the enzymes, and were poorly designed, according to the researchers. The majori...he researchers concluded that all six studies were poorly designed, which limits the ability to draw conclusions about how differences in CYP450 genes influen...

A New Strategy to Control Breast Cancer

...present in a form of breast cancer, which responds poorly to current therapies. TACE (tumor necrosis facto...“Women with those types of tumors would seem to be poorly served by existing treatments and may stand to benefit from therapies that are based on the inhibiti...

New Therapy to Treat Patients With Severely Elevated Cholesterol Levels

...ts who suffer from homozygous FH typically respond poorly to standard drug therapy and have a very high risk of premature cardiovascular disease. Homozygous FH is caused by loss-of-function mutations in both alleles of the LDL receptor gene. It is a rare form of hypercholesterolemia affecting approximatel...

Benefits of Diachrome for People With Type 2 Diabetes

...-day study examined thirty-six overweight or obese poorly controlled patients with type 2 diabetes taking Diachrome who were already receiving oral anti-diabetic drug(s). The results also showed a significantly greater reduction in the total area under the curve for glucose (AUCg) during the oral glucose to...

New MRI Technique Measures Intracranial Pressure in Brain Disorder

... non-invasive way to study a relatively common and poorly understood neurological problem." Chiari malformation is a condition where lower parts of the brain, the brainstem and the cerebellum, protrude downward into the spinal column. In the past, it was estimated that the condition occurs in about seven...

Law Professor Finds Home Health Care Workers Have Few Legal Protections

... considered low-skill work, Smith said workers are poorly paid, and receive few if any benefits. Depending o...t fund health care for the elderly on the backs of poorly paid workers," she said. "All too often, when policymakers consider home health care work, they focu...

Montreal Researchers And US Develop Model Of Key Immune-System Component

... organization and functioning of the phagosome are poorly understood." By analyzing a cell line of phagocytes from the Drosophila fruit fly, a common biological model, the researchers identified more than 600 proteins that may be involved with the operation of the phagosome. They then constructed a detai...

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