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Tag: "pivotal" at medical news

Drug to Prevent the Onset of Arthritis

...ts the molecular pathway and an enzyme that play a pivotal role in the onset of the condition. Researchers from Cardiff University conducted research to better understand the molecular pathway involved in the onset of arthritis. Early research has shown activity levels of two enzymes, MMP-2 and MMP-9, are ...

Drug to Delay the Onset of Arthritis

...ts the molecular pathway and an enzyme that play a pivotal role in the onset of the condition. Researchers from Cardiff University conducted research to better understand the molecular pathway involved in the onset of arthritis. Early research has shown activity levels of two enzymes, MMP-2 and MMP-9, are f...

New advance in prostate cancer management

...e prostate cancer will be. The technique will be pivotal in developing a test for prostate cancer aggressiveness which may ultimately prevent thousands of men undergoing unnecessary surgery, with its often associated severe side effects including incontinence and impotence. Prostate cancer is now the mos...

Early Awareness About Weight Management Needed To Tackle Lifelong Obesity

...se.The years before adolescence, then, emerge as a pivotal time for preventing a lifetime of excess weight -- for both biological and social reasons. For one thing, younger children are more willing to listen to adults and less susceptible to peer pressure, making it easier to convey this message: ''There's...

Gene Can Keep Brain Cells Alive

... of chemical stress, showing that the gene plays a pivotal role in keeping dopamine cells healthy. The authors point out that if the cells are subjected to oxidative stress, then the DJ-1 gene turns on the production of the antioxidant peptide, glutathione. When acting in this way, the DJ-1 protein can als...

Distinguished Scientist Award Conferred on University of Rochester Scientists for Work on Preventing Cavities

...r. Koo's work in this area helps us understand the pivotal role of nutrition in the development and prevention of dental decay," said Cyril Meyerowitz, D.D.S., M.S., head of the Eastman Department of Dentistry and director of Eastman Dental Center. Marquis is a microbial physiologist, who focuses on how the...

Resistant Influenza strains creates panic in US

... Association. Amantadine and rimantadine were the pivotal drugs used against influenza A. Statistics show that about 10-15% of the U.S. population suffers due to flu every year, and about 31,000 people die of it. Vaccination is considered the best strategy to prevent infection. It was found that 91% of ...

Ovarian Cancer Research Faces Funds Crunch

... by international standards. Hence therefore it is pivotal that such fun runs and ribbons are necessary to add to the research funding. This also has another advantage of making the participants to feel involved in finding a solution to the ubiquitousness of cancer. They ply a very important role in creating...

Carotid Stenting Can Help Patients With Silent Disease

...ry stenting for symptomatic patients following the pivotal ARCHeR trial, which enrolled a significantly smaller number of patients at centers with expert experience in carotid artery stenting. The larger CAPTURE trial was designed to determine the safety and efficacy of carotid stenting among a broader group...

Cholesterol Plays An Important Role In Finger and Toe Development

...opment of fingers and toes. The attachment of this pivotal chemical to a specific development protein is the key to proper digit development. Mice devoid of cholesterol developed digits in wrong places, in addition to extra digits. The results of this interesting study have been found in the online edition o...

Molecular Basis Of ALS Found

... long overlooked part of the SOD1 protein, plays a pivotal role. The ALS mutations appear to predispose SOD1 to form incorrect disulfide bonds that lead to aggregation of the protein and perhaps initiation of the disease. If these ideas are borne out, our next step is to look for therapeutic approaches that ...

Animal Study Found Cure For Huntington Disease

... and lead author in the study. This work is also pivotal for the individuals and families affected by Huntington disease. ‘Patients of this disease should know that this is a research milestone for all and that this work brings the field closer to finding effective treatment for a devastating disorder’, sa...

Abnormal Abeta - Protein Level in Human Brain Trigger Alzheimer's Risk

...llmark of Alzheimer's disease and believed to be a pivotal cause of the condition. Tests that measure Abeta levels in the cerebrospinal fluid have been available for some time. However, those fixed assessments of Abeta gave no indication of whether the flood of Abeta in patient's brains came from an increase...

Addition Of Budesonide To Formoterol Reduces Risk Of Mortality

...ta from the analysis of combined data from the two pivotal Symbicort(R) studies, announced today at the 5th International Multidisciplinary Conference on Chronic Obstructive Pulmonary Disease (COPD5), reveals that budesonide added to formoterol (Symbicort(R)) and/or terbutaline significantly reduces mortalit...

DNA-bound p53 Tumor Suppressor Protein Structure Determined

...ointing to this region of the p53 protein as being pivotal to its anti-cancer activity. Clearly, a detailed view of the p53 protein in direct contact with DNA could provide important insights into preventing and treating an array of human cancers. To date, however, despite having learned a good deal about ...

Only A Few Differentiating Factors Between Adult And Stem Cells

...ntenance of embryonic stem cell identity also play pivotal roles in the induction of pluripotency" in other body cells, he explained. The researchers selected 24 genes--all previously found to play a role in early embryos and embryonic stem cell identity--as candidate factors that might give body cells the...

Idursulfase Is Effective Treatment for Hunter Syndrome

An article reporting results from a pivotal clinical trial that helped gain U.S. Food and Drug Administration approval for the first treatment for Hunter disease has been// published online by the journal Genetics in Medicine. Lead author is Dr. Joseph Muenzer, an associate professor in the ...

Immune Cells Destroy Bone In Gum Disease

...igand, (RANKL)-mediated osteoclastogeneis, and the pivotal role it plays in inflammatory bone resorption. The aim of this study, which will be published in the September issue of the American Journal of Pathology, was to identify the cellular source of RANKL in the bone resorptive lesions of periodontal dise...

Results for Wet Age-Related Macular Degeneration Show Significant Vision Improvements

...dence.” Data from the two randomized, controlled pivotal Phase III clinical trials of Lucentis (ranibizumab injection) shows that at one year, 95 percent of patients treated with Lucentis did not lose vision. Of these patients, 55 percent maintained their vision (defined as a loss of less than 15 letters i...

Declining Incidence of stroke in Australia

...by 2017 due to the ageing of the population. The pivotal eleven-year Perth Community Stroke Study, conducted from 1989 to 2001, focused on the trends of strokes in both men and women, and the frequency of risk factors that play a key role in the incidence of stroke. The project involved collaboration betwe...

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