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Tag: "phase" at medical news

A new century of Alzheimer's disease research

...d, and in 2006 the company reported results from a phase II clinical trial enrolling 207 patients with mild...ings, Myriad Genetics launched a 1,600-participant phase III clinical trial in the summer of 2006, describing it as the largest placebo-controlled study ever...

Maxygen Initiates Phase IIa Clinical Trial of MAXY-G34 in Breast Cancer Patients

...ygen, Inc. today announced that it has initiated a phase IIa trial to evaluate the efficacy, safety and tolerability of MAXY-G34 in the treatment of chemotherapy-induced neutropenia . MAXY-G34 is a novel pegylated granulocyte colony stimulating factor (PEG-GCSF) shown in preclinical and Phase I studies to ...

Ambitious Gastric Cancer Research Project Proposed in Singapore

... S$1.5 billion has been set aside for the second phase of the Biomedical Sciences Initiative, which aims to position Singapore as a leader in scientific and medical research....

India's Share in Global Diabetes Research is One Percent

..., Dr Reddy's Laboratory, Hyderabad is in the third phase of clinical trials of a new class of anti-diabetic... intra-nasal insulin spray Nasulin in its second phase of clinical trials for type-2 diabetes. The editorial says that diabetes, heart disease and cancer...

New "second-line" AIDS Drug Shows Promise in Trials

...atients in two 48-week trials, the third and final phase of a long and complex process to assess new drugs for safety and effectiveness. The volunteers in the DUET 1 and 2 trials are divided into two groups. Half receive etravrine and half a dummy, lookalike pill, a placebo. In addition, all receive tw...

New Drugs Show Promise in Fighting Drug-Resistant HIV

...y 7th special HIV/AIDS issue. The multinational phase III clinical trial, which involved 18 nations and ...se who received TMC114 alone. The results from the phase III clinical trial will be submitted to regulatory authorities, which must grant their approval befo...

Drug Firm on the Threshold of Developing Dengue Vaccine

...ying. The Thai trials will be part of the second phase of the process. The vaccine was tested on 500 people in the United States during the first phase and proved safe and effective, Stephenne said. Once the Thai trials are completed, the vaccine will ...

Gene Therapy Eradicates Pancreatic Cancer in Mice

...he authors report. Dr. Abbruzzese says that the phase I clinical trial will advance under a National Cancer Institute Specialized Programs of Research Excellence (SPORE) grant in pancreatic cancer. SPORE awards are designed to translate scientific findings into the clinic. "There are no good options f...

Roches Arthritis Drug Successful in III Stage Trail

... arthritis drug Actemra has proved successful in a phase III clinical study. Actemra helps relieve symptoms of rheumatoid arthritis in difficult-to-treat patients in a clinical study thus bringing it closer to regulatory approval. The Radiate study was conducted over 24 weeks with 498 patients with diffi...

Hyperthermia With Chemotherapy Improves Sarcoma Healing

...ffectiveness of local, deep hyperthermia proved in phase III study . Hyperthermia, combined with chemothe...ed the results of the first, randomised, worldwide phase III study in which the effectiveness and superiority of the combined-therapy methods are proven, in ...

Researchers Find New Target for Anti-cancer Drugs

...o IL-6 which could be used to neutralize IL-6. A phase II trial is underway testing a monoclonal antibody against IL-6 for patients with multiple myeloma, a cancer that depends on IL-6 but is not known to have a connection to the ras oncogene. If the results of this trial are positive, studies might begi...

Value Meal Would Lower Drug Costs

...and Cohen are currently conducting such a study, a phase I trial of the combination of oral sirolimus (rapamycin) taken with grapefruit juice, which contains substances that delay the breakdown of many drugs. Dozens, perhaps hundreds, of drugs ought to be studied in this way, the authors said. "If we und...

Orthodontic Treatment is Better During Adolescence

...ly does not appear to have any advantages over one phase treatment. Prominent upper front teeth may be due to many different combinations of jaw, tooth and lip positions. Without treatment the teeth can become damaged over time, but it appears that there is no harm done in waiting for early adolescence be...

Gardasil Could Be Effective, but Aggressive Marketing Raises Ethical Concerns

...cipal investigator at the clinic site for both the phase two and phase three trials for both Gardasil and Cervarix. She shares the concern of many that the hype could le...

Food Cravings are Linked to Weight Managenemt

Findings from the first six-month phase of a calorie-restriction study conducted at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University suggest thataccepting food cravings and keeping them in check may be an important component of weight managemen...

Artificial Trans Fat Banned in Chain Restaurant in King County

...d last December, King Countys artificial trans fat phase out occurs in two steps. Food service establishments have until April 1, 2008, to switch to trans-fat-free frying oils and shortenings and until February 1, 2009, to remove artificial trans fat from other products. "This legislation is being driven...

Weight Management Achieved by Controlling and Not Suppressing Food Cravings

...ponent of weight management. The first six-month phase of the study provides new insights into food cravings, specific types of foods craved, and their role in weight control. Cravings are really normal; almost everyone has them, says corresponding author Susan Roberts, PhD, director of the USDA HNRCAs...

Interactions Between Food and Drugs Could Lower Drug Costs

...and Cohen are currently conducting such a study, a phase I trial of the combination of oral sirolimus (rapamycin) taken with grapefruit juice, which contains substances that delay the breakdown of many drugs. Dozens, perhaps hundreds, of drugs ought to be studied in this way, the authors said. "If we un...

Etanercept Reduces Psoriasis

...ence Center at Houston, and colleagues conducted a phase 3 randomized, double-blind trial with an open-label extension . After a 12-week period during which 618 patients with moderate to severe psoriasis were randomly assigned to receive either placebo or 50 milligrams of etanercept twice weekly (the curr...

Protein That may Prevent Eye Damage in Premature Babies Identified

... University of Goteborg are currently conducting a phase 1 clinical study to evaluate the use of IGFBP-3 in combination with IGF-1 to examine the effects on prevention of retinopathy in premature infants, based on the clinical findings in our study," Smith said. "This work suggests that both IGF-1 and IGFB...

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