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Tag: "phas" at medical news

Emphasis to ban Drugs ads by Doctors

An increase in the number of advertisements by the drug companies has prompted the doctors to urge the government to ban prescription drug ads from television, news papers and magazines. American Medical Association's New Jersey delegate Dr. Angelo agro said that such ads can undermine doctor's credibility especially if physician thinks an advertised drug isn't the best choice for a patient who d...

Emphasis on eating pattern

A study of middle-aged women suggests that those who eat the healthiest diets also eat a lot of fruit and a wide variety of foods. The Healthy Eating Index (HEI) is a measure that US nutritionists have developed to assess the quality of someone's diet. This emphasises your eating pattern rather than intake of specific nutrients. You get marks out of ten for servings of grains, vegetables, fruit,...

FDA approves Phase 0 trial which tests experimental drugs on humans

Good news for researchers has FDA has approved testing of small quantities of experimental drugs in human beings. Approval of small quantity drug clinical trial will be very helpful for researchers to// understand the path of the drug in the body and its efficacy if the drug is proved effective in small quantities researchers can proceed with a phase I clinical trial. ..Researchers feel that e...

SARS-Free Taiwan to Mark End Phase of Global Fight

The WHO said on Friday it expected to announce the removal of the island from what was once a long list of infected regions or countries where new cases of the deadly virus had been reported within the previous 20 days. ..The normal incubation period for the disease is 10 days, and twice that time is the mandatory transmission-free period before //the WHO can declare a local emergency situation...

S. Africa AIDS in 'death phase'

The AIDS epidemic in South Africa is entering the "death" phase as mortality outstrips new infections, say scientists..."South Africa is experiencing a devastating epidemic -- the world's worst -- and this is just the beginning,'' said researchers . ..South African President Thabo Mbeki's government has been criticized for its lackluster approach to tackling the disease, //which has already infec...

Spray on contraceptive clears Phase I trial

An Australian drug delivery company called Acrux specializes in administering medicines// through the skin. It has recently reported positive results for its Phase I clinical results of a contraceptive for women in the form of a spray. ....The novel contraceptive spray called Nestorone MDTS is being developed in collaboration with a US-based research group 'The Population Council'. Interestingly...

Phase 3 trials of two multi-kinase inhibitors against cancer

Sorafenib and stutent multi-kinase inhibitors against cancer is undergoing phase 3 trials// and these two drugs gained more appreciation in this years ASCO (American Society of Clinical Oncology) conference. This drug is gaining interest due to its multiple mechanism of action – known as Multi-kinase inhibitors. These drugs are in trial against different types of cancer and are found to be very e...

Antigenics Pharmaceuticals plans for Phase III trial of its Melanoma vaccine

Antigenics Pharmaceuticals is to start its Phase III cancer vaccine trial against Melanoma which is a type of skin cancer. Oncophage is the new skin cancer vaccine developed by Antigenics.// The vaccine trial of Oncophage which was conducted in 322 patients failed to meet the required statistically significance results compared to prolongation in survival and the vaccine was not shown to have any...

Need For Social Churning Emphasized In CMC Meet On ‘Leadership In Healthcare

The Secretary of the National Commission on Macroeconomics and Health, K Sujatha Rao, emphasized the need for the Union Government to make mandatory a comprehensive Universal Health Insurance System for the people//. ..She advocates the utilization of 9 % of the GDP on health and adopt a cross-sectoral approach which should include education, socio-economic growth and provision of basic infrastr...

Phase II trails of new HIV vaccine to be held in South Africa

In a step further to combat the AIDS epidemic, South Africa's first Phase II HIV vaccine trials were launched by charitable group the International AIDS Vaccine Initiative (IAVI) and U.S.-based Targeted Genetics Corporation. // .. ..The trials will test the safety of "tgAAC09" is a preventive HIV vaccine candidate that is based on HIV subtype C, the subtype of the virus most prevalent in southern...

WHO Calls For Greater Emphasis On Combating AIDS

The Asia-Pacific nations have been called upon by the World Health Organization (WHO) to review the progress made by them with regard to combating AIDS.// This is required to wage a more effective campaign against HIV/AIDS. ..Shigeru Omi, Director of the WHO's Western Pacific Region office in Manila, said the theme for this year's World AIDS Day Thursday, "Stop AIDS, Keep the promise" was a call...

Jalgaon: Third Phase Of Culling Operations Begin

The third phase of culling operations targeting 3.1 lakh chickens in 354 villages in Jalgaon district began on Saturday even as the Government assured people that there was no cause for panic.// District Collector Vijay Singhal said that the villages had been identified as being within a radius of 10 km as specified by the High Security Animal Diseases Laboratory in Bhopal. ..This third phase is...

Phase 1 Drug Trials on Humans to Be Made Public

World Health Organization (WHO) asked the pharmaceuticals companies and academic institutions to reveal all information on all clinical drug trials on humans. // All drug trails including the details about Phase I trials, initial toxicity tests that were conducted on healthy humans are to be registered on independent registers as soon as they begin. Though this decision is not been made legal but...

Importance of Hygiene to Be Emphasized For Health Acre Workers

According to the research conducted by Mary-Louise McLaws, of the University of New South Wales it was found that health workers often failed to wash //their hands after every patient which resulted in increased cross infections among patients. She said that failing to wash their hands is due to the attitudes learnt in childhood. ..If they were taught from a young age to wash their hands to pro...

Lupin Gets DCGI Nod For Phase II Clinical Trials On Desoside-P

Pharma company Lupin Ltd today said it has received approval from the Drugs Controller General (India) (DCGI) to conduct Phase II clinical trials for the molecule LL-42 18 (Desoside-P).// ....The company received permission to continue Phase II clinical trials on the Psoriasis pure compound, LL-42 18, after DCGI found the clinical Phase I data of the molecule to be satisfactory... ..Lupin inform...

Cadila to Commence Phase I Clinical Trials On ZYH2

Cadila Healthcare Ltd today said it has received approval from Drug Controller General of India (DCGI) to conduct Phase I clinical trials on its New Molecular Entity// (NME) - ZYH2, used for treating diabetes. ....In pre-clinical studies on 'ZY H2' displayed that it has the potential to improve insulin resistance and lower blood glucose in diabetic conditions without causing hypoglycemia, the co...

iGATE Completes Phase I Testing Of Meningitis Vaccine

Contract research firm iGATE Clinical Research International today completed the Phase I clinical trial of a new meningococcal-A conjugate vaccine. // ....The project, which is being done in partnership between the World Health Organization (WHO) and the Program for Appropriate Technology in Health (PATH), an American NGO based in Seattle aimed at eliminating epidemic meningitis in sub-Saharan A...

China’s AIDS vaccine-successfully finishes first phas

According to the government health officials, initial clinical trials show that China’s first AIDS vaccine is safe and probably effective//. ...."Forty-nine healthy people who received the injections showed no severe adverse reactions after 180 days, proving the vaccine was safe," said Zhang Wei, head of the pharmaceutical registration department of the State Food and Drug Administration (SFDA)....

Rise in Esophageal Cancer is emphasized by Richards’ deat

The death of the ex-governor of Texas, Ann Richards marks the rapid increase in esophageal cancer cases in the US. ..She died 6 months after being diagnosed with esophageal cancer.// Only 16 % or around 2,200, of the 14,000-esophageal cancer cases diagnosed in the US this year, will survive in 5 years. ..There has been a 6-fold annual rise in the number of esophageal cancer cases over the past 2...

ADHD Treatment -Phase 3 data on Lisdexamfetamine dimesylate Presented

The investigational ADHD treatment, lisdexamfetamine dimesylate (also known as NRP104 or LDX) by Shire plc and its collaborative partner// New River Pharmacuticals has yielded a good response in children with Attention Deficit Hyperactivity Disorder, it was announced today. ....The data was presented at a national meeting of child and adolescent psychiatrists last weekend. ....The study was don...

Pharmac to Phase Out Aropax, Well-known Antidepressant

Government Drug Agency, Pharmac, is in the process of doing away with a commonly used antidepressant, Aropax. // ....Pharmac intends to phase out the ‘Aropax’ brand of paroxetine and bring in the generic alternative ‘Loxamine’. It is estimated that Aropax is used by about 49,000 New Zealanders. ....This move has drawn flak from psychiatrists in Australasia. Yet, the agency maintains that both...

Vandetanib Study Enters Third Phase

The Phase 3 study of the drug Vandetanib, marketed by London company AstraZeneca PLC// has begun. .. The study will cover 508 patients of lung cancer in whom the first-line treatment has failed. The study extends over 20 countries and 20 sites. .. The patients who have a recorded a case of locally advanced or metastatic non-small cell lung cancer will be given the once-daily drug Vandetanib in...

Care During Last Phase of Life Needs to Be Uplifted

Medical specialists have underlined the urgency to uplift end of life care. In the current issue of BMJ, doctors have waxed eloquent on the flaws// in the healthcare system that do not adequately care for people in the last lap of life. .. ..Our health care systems do not reliably meet the needs of people living with serious illness in the last phase of life, write Sydney Dy and Joanne Lynn, two...

Australian Food Industry Plans to Phase Out Trans Fats

A meeting of food industry representatives in Sydney has come out with the decision to gradually phase out trans fats from their products//. The move follows similar ones followed overseas by other food companies. ..The industry in Australia is also coming under pressure from the federal government to deal with the issue, or else face regulatory requirements. This would force levels of trans fat...

NIH Announces Phase III Clinical Trial of Creatine for Parkinson's Disease

The NIH National Institute of Neurological Disorders and Stroke (NINDS) today is launching a large-scale clinical trial to learn if the nutritional supplement creatine// can slow the progression of Parkinson's disease (PD). While creatine is not an approved therapy for PD or any other condition, it is widely thought to improve exercise performance. The potential benefit of creatine for PD was ide...

UN Secretary Emphasize Action Against Tuberculosis

UN Secretary General Ban Ki-moon urged governments to join the anti-tuberculosis global plan, which would save 14 million lives in coming years as// the disease has become extremely drug-resistant. ....Ban's message aimed at stressing the importance of World TB Day on Saturday. The World Health Organization (WHO) recently reported about the rise in the extensively drug resistant strain of tuberc...

Intercell to Begin Phase II JE Vaccine Trials in India

Austrian biotech major, Intercell and its partner Hyderabad-based Biological E. Ltd. announced that they have obtained regulatory clearance to start// a pediatric phase II clinical trial for Intercell’s novel Japanese Encephalitis vaccine in India. ....The randomized and controlled study aims to demonstrate the dose, safety and immunogenicity of Intercell’s JE vaccine compared to a locally produ...

Crucell's Rabies MAb Enters Phase I Trial in India

Dutch biotechnology company, Crucell N V’s Rabies monoclonal antibody (mAb) product has entered a phase I clinical study in India, four months after launching// a similar study in the US. .. ..Crucell has developed a human monoclonal antibody product for the post-exposure prophylaxis of rabies, using Crucell’s MAbstract and Crucell’s PER.C6 technologies. This second phase I study is closely link...

FDA Re-Emphasizes Warnings to Consumers on Risks of Pet Turtles

The Food and Drug Administration (FDA) is urgently reminding the public that contact with baby turtles can pose a serious health risk to infants//, small children, and adults with impaired immune systems as they can be natural hosts to Salmonella, a group of bacteria that can cause severe illness and death. Recently, a four-week old infant in Florida died of infection traced to Salmonella pomona,...

CRN Emphasizes Importance of Folic Acid Benefits

WASHINGTON, The Council for Responsible Nutrition (CRN) today responded to a study and accompanying editorial on folic acid and the prevention of cancer in the June 6 issue of the Journal of the American Medical Association (JAMA) by urging the scientific research community, the media, and the government not to jump to conclusions that would undo the important strides made in recent years in enc...

Cell Genesys Reports Additional Data From Phase 2 Clinical Trial of GVAX Immunotherapy for Pancreatic Cancer

Cell Genesys, Inc. (Nasdaq: CEGE) today announced follow-up data from a Phase 2 clinical trial of GVAX immunotherapy for pancreatic cancer which was conducted by the Johns Hopkins Sidney Kimmel Cancer Center. The trial enrolled 60 patients with operable pancreatic cancer who received GVAX after surgical resection of their tumor and adjuvant radiation and chemotherapy. The median overall survival...

Combination Improves Survival of Metastatic Melanoma Patients: Phase II Study

CHICAGO According to study findings presented today at the 2007 American Association of Clinical Oncology, two chemotherapy drugs combined with an agent that prevents the growth of blood vessels, significantly delayed the spread of tumors in patients with metastatic melanoma. ......In this phase II clinical trial of 53 patients, tumor growth was delayed by almost six months, whereas, typically...

Surface Logix Commences Phase 2a Clinical Trial of SLx-2101 in Raynaud's Disease

BOSTON, -- Surface Logix Inc. today announced the initiation of a Phase 2a clinical trial for SLx-2101 in patients with secondary Raynaud's disease. SLx-2101 is a novel , long-acting PDE-5 inhibitor being developed for the management of diseases associated with vascular dysfunction such as Raynaud's, a vasospastic disorder of small blood vessels leading to a marked reduction of blood flow to area...

Avicena to Advance Huntington's Disease Clinical Program into Phase III

Avicena Group, Inc. (OTC Bulletin Board: AVGO), a late stage biotechnology company that develops central nervous system therapeutics for neurodegenerative diseases, announced today the selection of the optimal dose of HD-02, its novel drug candidate for the treatment of Huntington's Disease. ...This dose was determined in an open-label dose escalation study, led by Dr. Steven Hersch and Dr. Dia...

Alteon Initiates Phase 2 Trial of ALT-2074 in Diabetes and Haptoglobin 2-2

Alteon Inc. announced today that it has dosed its first patient in a 60-patient Phase 2 clinical trial (Study 201) of ALT-2074, its lead glutathione peroxidase mimetic, in diabetic patients with a variant of haptoglobin that renders them at high risk for cardiovascular complications. ... This dose escalating study is designed to evaluate ALT-2074's ability to lower inflammatory cardiovascular...

UK to Support Third Phase of India's AIDS Control Programme

The Department for International Development (DFID) in Britain has announced a funding of 102 million pounds (Rs.816 Crore) over five years in support of the third phase of Government of India's (GOIs) National AIDS Control Programme (NACP III). ......The NACP III is a comprehensive prevention, care and support programme to halt and begin to reverse the AIDS epidemic in India by 2012. The ann...

Replidyne Announces Positive Phase I Results for Topical Antibiotic REP8839

Replidyne, Inc. today announced results from three Phase I trials studying REP8839, a novel topical antibiotic that has shown potent in vitro activity against major skin pathogens including methicillin-resistant S. aureus (MRSA). ......The results of the Phase I trials show that topically applied REP8839 appears safe, well-tolerated and associated with low systemic exposure, or drug absorption...

Novagali Pharma Presents Phase III Clinical Trial of Vekacia(R) for Vernal Keratoconjunctivitis

Novagali Pharma, an emerging pharmaceutical company specialized in ophthalmology presents positive results of its pivotal phase III clinical trial positive results from the Phase III clinical study of Vekacia(R) in children suffering from Vernal Keratoconjunctivitis (VKC) at the XIV Afro-Asian Congress of ophthalmology (AACO) held from June 20 to 25 2007 in Marrakech (Morocco). ......VKC is a s...

LifeCycle Pharma to Initiate Phase II Clinical Trial of LCP-Tacro for Organ Transplantation

LifeCycle Pharma will initiate a Phase II clinical trial of LCP-Tacro for the prevention of organ rejection in kidney transplant patients following the update of its initial Investigational New Drug Application (IND) in the United States (U.S.) ......LifeCycle Pharma has also reached protocol agreement with the U.S. Food and Drug Administration (FDA) for its first Phase II trial in kidney transp...

Phase II Data Show Efficacy and Tolerability of Tapentadol in Chronic Pain Treatment

The German pharmaceutical company Grunenthal GmbH presented the first clinical evidence for the efficacy and tolerability of tapentadol ER (extended release) for patients suffering from chronic pain at the Annual Congress of the European League Against Rheumatism (EULAR), 13-16 June 2007, Barcelona, Spain. Tapentadol, a centrally acting analgesic, is the first of its kind, combining two analgesi...
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