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Tag: "peripheral" at medical news

A Novel System For Clinical Banking Of Umbilical Cord Blood

...nd is used as an alternative to the bone marrow or peripheral blood for treatment of several onco-hematological diseases. Because of the limited number of CD34+ hematopoietic stem cells present in UCB units and of the elevated costs of cryopreservation, it is of paramount importance to select the UCB units th...

Bortezomib for salvage therapy against progressive myeloma

...ades 3?4 toxicities (thrombocytopenia, leucopenia, peripheral neuropathy and vasculitis) were observed in 7 patients, but no patient interrupted the treatment due to side effects. The study indicates that the use of bortezomib, in this specific setting, is generally safe and may be effective in a relevant pro...

The potent anti-leukemia activity of Berbamine

...ccumulation of mature and immature granulocytes in peripheral blood and bone marrow due to uncontrolled growth // and resistance to apoptosis. The dysregulated activity of the bcr/abl oncoprotein tyrosine kinase, which is encoded by the bcr?abl fusion gene, has been shown to be responsible for the malignant ph...

Carnitine deficiency in children and adolescents with type 1 diabetes

... the cells to insulin.// The use of glucose by the peripheral tissues and proper metabolic control in Type 1 diabetes has potential impact on long-term complications. In diabetes, the metabolism of carbohydrate and fat is abnormal and an association between the proper metabolic control and the development of ...

Association Of Breast Arterial Calcifications With Diabetes And Hypertension

...ere are calcium deposits in the media layer of the peripheral arterioles and this condition is called M?nckeberg medial// calcific sclerosis or medial arterial calcification. Many groups have reported the association of BAC with diabetes and cardiovascular risk, but there are few reports related to BAC and hype...

Age-Dependent Alterations Not Specific For Alzheimers Disease

...evidence indicates that AD is also associated with peripheral vascular changes //that might be important markers in tests of given pathophysiological hypotheses. Researchers from the Faculty of Medicine, University of Szeged, Hungary, hypothesized that the onset of AD affects cholinergic microcirculatory patt...

Malaria infection can accelerate HIV infection and disease progression

...a. In pregnant women HIV-1 is associated with more peripheral and placental malaria, higher parasite densities, more fever, and increased risks of adverse birth outcomes. Researchers had previously worked on seven fold higher HIV-1 viral loads in adults with acute malaria compared with those without, and that t...

Ambiguous Efficacy Of Opioid Drugs In Chronic Inflammatory Joint Pain Relief

...ral analgesic to their target spots throughout the peripheral tissue of joints. Recently a study, published in ...and Rheumatism, was conducted to determine whether peripheral administration of the endogenous - opioid peptide endomorphin 1 could reduce knee joint pain, using ...

A new anti diabetic drug on the anvil

...iated with glucose dependent insulin secretion and peripheral insulin resistance. While no DPP-IV inhibitor has been approved for marketing till date, among the scientific community DPP-IV inhibitors are expected to offer significant potential for being the therapy of choice, once approved. The Phase I study w...

Use of a fast-acting insulin analog to control diabetic ketoacidosis in Children

...ntravascular volume up to the normalization of the peripheral perfusion. Once cardiovascular stability was achieved, the child was alert, and vomiting has stopped, oral rehydration was started. Cerebral edema, the most feared complication of DKA, did not develop in the patients during this study. Also, there we...

Diabetics increases likelihood of falling and associated accidental injury in elders

...reased fall risk. It has been speculated that with peripheral nerves that can affect the sensation in diabetic people's feet, known as peripheral neuropathy, could be the mechanism at fault for the higher fall rate in diabetic patients. Followi...

Incidence of breast cancer increasing in urban India

...pausal women an enzyme called aromatase present in peripheral tissues such as fat, muscle and liver produces oestrogen that triggers breast cancer. At the "Viva for Eva" - Breast Cancer Summit '05, doctors stressed that women coming from families where a mother or sister below the age of 50 has breast cancer ...

Diabetic Amputation May Reduce If Free Screenings Are There

...ll set to start a free screening program to detect peripheral arterial disease (PAD) on time to prevent loss of ... life-threatening vascular disease. If undetected, peripheral arterial disease can lead to amputation and increase a person’s risk of having a heart attack and st...

Alzheimer's Disease Caused By Insulin Increase

... AD) in plasma and cerebrospinal fluid. "Moderate peripheral hyperinsulinaemia (increased levels of insulin) provoked striking increases in CNS (central nervous system) inflammatory markers," the authors report. "Our findings suggest that insulin-resistant conditions such as diabetes mellitus and hypertension ...

Quitting Smoking Made Easy By Track Of New Chemical

... The study showed that levels of MAO B in smokers' peripheral organs - the heart, kidneys, spleen and lungs - were reduced by 40 to 50 percent compared to non-smokers. The results of tracking [MAO] A showed that is fairly well intact in all of the organs but the lungs. The levels in smokers were 50 percent l...

Elevated Insulin Levels To Influence Levels Of Inflammatory Markers

... AD) in plasma and cerebrospinal fluid. Moderate peripheral hyperinsulinemia (increased levels of insulin) provoked striking increases in CNS (central nervous system) inflammatory markers, the authors reported. Their findings suggest that insulin-resistant conditions such as diabetes mellitus and hypertension...

Arsenic in drinking water

...ed that arsenic causes other, less severe forms of peripheral vascular disease. According to some estimates, arsenic in drinking-water will cause 200,000 – 270,000 deaths from cancer in Bangladesh alone (NRC, 1998; Smith, et al, 2000). Prevention And Control Absorption of arsenic through the skin is minima...

Toll-like Receptor (Tlr3) Attachment Leads To Lethal Encephalitis

... following this challenge, the viral burden in the peripheral blood was increased in Tlr3 mice compared with wild type mice. Analysis blood cytokine levels showed increased levels of inflammatory cytokines in wild type, compared with Tlr3 mice early in infection. The results indicate that Tlr3 did have a role i...

Wearing High Heels May Be Dangerous To Health

...the hypothalamus and some areas of the central and peripheral nervous system. Dopamine and its agonists play an important role in hormonal, cardiovascular, renal and central nervous system regulations. The dopamine transporter mediates the acceptance of dopamine into neurons and is often the target of various d...

Amputation may depend on availability of vascular surgeons

Patients suffering from peripheral arterial disease may lose their limb to amputation...ons, report less number of cases where patients of peripheral arterial disease have suffered through an amputation. Peripheral arterial disease (PAD) is often no...

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