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Tag: "peptide" at medical news

Rheumatoid Arthritis: Early Aggressive Treatment Needed

...ity, and the presence of anti-cyclic citrullinated peptide antibodies. Then, using the area under the curve (AUC), the diagnostic performance of the prediction rule was evaluated. A prediction score, ranging from 0 to 14, was calculated for every patient in the group, with a higher score indicating a great...

‘Baby Food’ to Battle Obesiy

...he amounts of a hormone named GLP-1; glucagon like peptide that was responsible for a feeling of satiety. The fiber also had a stimulating effect on the gene that was responsible for this hormone. In retrospect the rats under observation ate less and had a better blood lipid profile. Says Dr. Raylene Reime...

Man-Made Proteins Could Be More Useful Than Real Ones

...ngle chemical component—a methylene group—into the peptide backbone. “The fundamental insight from this st...pattern. The researchers found that the Zwit1-F peptide folded into a bundle of coiled helices that resembled those in natural proteins. In particular, Sche...

Bacteria Fighter Goes Where Antibiotics Can't

...umber and order of amino acids in an antimicrobial peptide determines how it recognizes and attacks an invadi... shown that removing amino acids from one end of a peptide can boost its antibacterial properties. However, these shortened peptides are also more deadly to re...

Vitamin D3 Protects Skin from Harmful Microbes

....” Gallo’s lab discovered that an antimicrobial peptide called cathelicidin is produced by wounds and is n...eers, and patients with disorders in antimicrobial peptide production such as atopic dermatitis and acne, are being studied to determine if vitamin D3 can impr...

Natural Antibiotics Yield Secrets to Atom-level Imaging Technique

...roscopy is used to construct a detailed image of a peptide or protein and to reveal how it sits in the cell membrane," providing clues for modifications that might make synthetic AMPs even more effective in overcoming ever-increasing bacterial resistance. For instance, rearranging parts of the molecule might...

Scientists Explore Ways to Reduce Insulin Resistance by ‘handcuffing’ Gens

...udies, have discovered that silencing a gene for a peptide involved// in insulin secretion will not only redu...wbacks associated with a high calorie diet. The peptide in question is ucocortin 3. This was discovered after ucocortin 2. Both are peptides produced in t...

$1.5 Million Grant to Yale for Narcolepsy-Neurotransmitter Study

...other disorders linked to neurons that produce the peptide hypocretin. “The activity of these hypocretin cells is important for enhancing cognitive arousal and resisting sleep, and they may also play a role in anxiety and body weight regulation,” said the principal investigator, Anthony van den Pol, neuros...

Inhibiting Blood to Save the Brain

...chool of Medicine have identified a fibrin-derived peptide that inhibits this specific inflammation process i...er the first episode of paralysis using the fibrin peptide prevented subsequent relapses. It also prevented further microglia activation and damage to myelin i...

Antioxidant Molecule Could Help Minimize Stroke-Linked Brain Damage

A novel peptide discovered by researchers at Weill Cornell Medical...no effect," Dr. Cho says. "That suggests that this peptide is working via inhibiting CD36 pathways." The exact mechanism by which SS31 inhibits CD36 remains ...

Hormone-based Heart Pill to Control High Blood Pressure

...riginating in the heart, called B-type natriuretic peptide (BNP). "Our formulation of an oral peptide is a technological accomplishment that really can advance the field," says John Burnett, Jr., M.D., ...

Penn Scientists Engineer Small Molecules to Probe Proteins Deep Inside Cell Membrane

...d cells important in clotting. When the designed peptide is inserted into the platelet membrane it binds to the portion of the integrin within the membrane, and subsequently perturbs another function in the clotting process downstream. "By having molecules that bind to the membrane-embedded portions of the...

Breast Cancer Vaccine Stimulates Potent Immune Response to Cancer Cells

..., M.D., Ph.D., and colleagues designed a synthetic peptide vaccine that stimulated an anti-tumor T cell respo...ne HER-2/neu, researchers administered a synthetic peptide vaccine during the early stage of tumor development. The experiment was effective in 100 percent of ...

HIV/AIDS- Possible Cure From Within

...an body itself. // Announcing the discovery of a peptide (chain of amino acids) derived from filtrate residues of kidney dialysis patients, lead researcher Frank Kirchhoff from the University of Ulm in Germany was quoted: “You want a lot of drug classes, because multi-drug resistant viruses are starting ...

Peptide Found in Human Blood Inhibits 60 Strains of HIV, Study Says

A peptide found in human blood inhibited 60 strains of HIV f...Francisco Chronicle reports. Researchers found the peptide can inhibit HIV strains that have developed resistance to existing medications --a discovery that co...

Brazil Spider Offers Hope for Those Suffering from Erectile Dysfunction

...ompared with control rats, those injected with the peptide showed a significant increase in penis pressure. The scientists also found an increase in nitric oxide within the two main cylindrical cavities that run the length of the penis and are called corpora cavernosa. The significance of the nitric oxide...

New Developments in Rheumatoid Arthritis

...ed a test to measure for anti-cyclic citrullinated peptide antibody, or anti-CCP. It is now being used as a diagnostic for rheumatoid arthritis. Scientists are now finding that patients have CCP antibodies months or years prior to the illness, suggesting a way to identify the disease before it starts and per...

Now a Drug to Stop the Feeling of Hunger

...ch makes people feel full . Researchers developed peptide BL-3020 as an analog to aMSH, a naturally occurrin...appetite, thus leading to natural weight loss. The peptide has already been patented in Europe and the U.S., and a commercial firm, Bioline RX Ltd. of Jerusale...

Pramlintide-A Boon to Restrain Fast Food Consumption

...other hormones involved in weight control, such as peptide YY and leptin, Weyer said. Research in obese rats suggests that amylin may restore the response to leptin, which is often lost in obesity. The hope is that this combination approach will help achieve even greater appetite control and weight loss....

Stress Protein Inactivation Cuts Alzheimer's Peptide in Mice

...ealed that stress boosts the production of a brain peptide critical to Alzheimers disease, a new study on mice has now shown that blocking a different brain peptide slows the stress-induced increases. The study, reported online in the Proceedings of the National A...

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