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Tag: "pathway" at medical news

Substance P May Pre-empt VIP in Regulating Temperature

An elusive neurotransmitter pathway in the skin may have been isolated by University o...regon. “What we’ve found is that the NK-1 receptor pathway is a major player in this response, and this finding could represent a paradigm shift. Our data impl...

Key Gene Controlling Eye Lens Development Identified

...r discovery helps to better unravel the regulatory pathway that controls normal lens formation,” said the paper’s senior author, Guillermo Oliver, Ph.D., a member of the St. Jude Genetics and Tumor Cell Biology department. “Specifically, it puts the Six3 gene at the top of the genetic cascade that controls t...

Turmeric to prevent arthritis and osteoporosis

...ints. It also showed effectiveness in blocking the pathway that affects bone loss associated with Osteoporosis. Turmeric may also be effective in tackling other inflammatory disorders like asthma, multiple sclerosis and inflammatory bowel disorders. The article, 'Efficacy and Mechanism of Action of Turme...

Revolutionary Eye Cancer Treatment

...ma experts thought that a mechanism called the p53 pathway triggered apoptosis in other types of cancer cells...er, the St. Jude team proved not only that the p53 pathway was activated in early-stage retinoblastoma, but that excessive levels of a molecule called MDMX blo...

Systemic Pre-Surgical Treatment Can Prolong Survival Of Kidney Cancer Patients

...roup, which meant that blocking the VEGF signaling pathway with bevacizumab might have resulted in feedback to the AKT pathway, which is known to be involved in cell signaling. 'At the moment, we don't understand what mechanisms are operating to bring about the response we have observed in patients,' said ...

Tidbits on Tarantula bites and fiery Pepper sensations!

...ering pain. The research aids understanding of the pathway of pain and expounds that new drugs to treat persistent pain can be evolved based on these new intriguing findings which has been reported by the online journal Nature. The tarantula venom and fiery chili pepper targets the same heat sensor on nerv...

Turmeric prevents rheumatoid arthritis: US study

...udy shows that the curcuminoid extract blocked the pathway that affects bone resorption. Source-IANS...

Regulatory Mechanism for Tumor Suppressor Protein Identified

...e control of cancer in humans. The new molecular pathway described in the study suggests intriguing approaches to diagnosing or intervening in the progression of many types of cancer. A report on the team's findings will be published online November 15 in the journal Nature. "The p53 protein is vital for ...

Limb Regeneration Exists Innately In All Vertebrates – Says Researc

.... "It could be that we could use the Wnt signaling pathway to dedifferentiate cells inside a body at the site...c amount of time," he says. "The fact is that this pathway is involved in cell proliferation, whether it is to generate or regenerate limbs, control stem cells...

Insect Protein Effective for Treating Heart Enlargement, Arrythmias

...which are costly and invasive. “By blocking the pathway that leads to overgrowth of cardiac cells, we have shown that it is possible to prevent the progressive deterioration of heart function and the development of abnormal heart rhythms.” said Chiamvimonvat, a physician who specializes in cardiac rhythm ...

Zinc – A New Key Player In Brain Circuitr

...hat interfering with zinc modulation of a synaptic pathway leads to a significant alteration in the phenotype of the animal." The three scientists added that the finding "puts a nice dent in the zinc armor, which held firm for more than 50 years." Source-Eurekalert SRI...

Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum

...start to divide because of a defect in a signaling pathway starting at the cilium” This sensory role of primary non-motile cilia has now become the model for many other diseases and syndromes, all of which trace back in many different tissues to defects in receptors or channels on the ciliary membrane, or t...

How Taste-buds Develop?

... engineered mice, they discovered that a signaling pathway activated by small proteins called Wnts is require...f taste-bud development in humans. The signaling pathway activated by Wnt proteins is critical to the development of many organ systems, and its inappropriat...

Study Uncovers Mutation Responsible for Noonan Syndrome

...AS and its downstream target, MAP kinase, the same pathway activated by PTPN11 mutations. 'These results are the first example of activating mutations in an exchange factor in human disease,' notes Neel, explaining that for families at risk for Noonan syndrome, the findings will aid in prenatal diagnosis a...

Tailor-made Cancer Treatment for Multiple Myeloma Patients Offered by Mayo Clinic

...singled out tumor specific alterations in cellular pathway by which drug bortezomib (Velcade) works.// This... newly diagnosed patients. "Now that we know the pathway the drug targets, and genetic mutations within this pathway that make patients respond better, we ar...

Study Explains How NSAIDs Halt Cancer Growth

...hibition did not appear to be the only anti-cancer pathway being targeted by the compounds. We, therefore, undertook a comprehensive review of NSAIDs in order to decipher the precise molecular mechanisms that were at work.” Using whole genome microarray analysis, Libermann and first author Luiz Zerbini, Ph...

The Outbreak of Pseudomonas Aeruginosa In An LA Hospital, Makes 7 Children Sick

...ors and other equipment that give bacteria an easy pathway to the body. "It's a group of patients that are very vulnerable," said Dr. Arjun Srinivasan, a medical epidemiologist at the U.S. Centers for Disease Control and Prevention. "They're very sick, so they are at risk of these infections. The care that...

Study Identifies Mechanism Which May Help Tamoxifen Work Better

...urvive the loss of estrogen. “Blocking the Notch pathway with a Notch inhibitor offers a new strategy to st...n be done by using a novel drug to block the Notch pathway while simultaneously controlling estrogen signaling through the estrogen receptor,” said Albain, dir...

Cellular Pathway Yields Potential New Weapon in Vaccine Arsenal

... helper T cells. But he didn’t know how often this pathway is used or how efficient it is. Now, a new study p...ward addressing these questions and shows that the pathway is so common that it could be a valuable new way of boosting vaccine efficacy. There are two types...

Unfolded Proteins May Protect Cells from Dying

...e pathway, and therapeutically this is the type of pathway you want to boost to protect cells from stress ind...that more aspects of the unfolded protein response pathway can be illuminated. While they found that the unfolded protein response initially protects retinal c...

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