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Tag: "overactive" at medical news

Researchers Find New Target for Anti-cancer Drugs

...unter added. The researchers discovered that the overactive ras gene was responsible for above-normal secretion of a factor known as interleukin-6 (IL-6). Scientists know a great deal about IL-6 and its functions in the body, but its link to oncogenic ras was unknown. In addition to finding that the ras onc...

Second-hand Smoke Exposure in Pregnancy Linked to Kids' Psychological Problems

...are hard to sooth as infants. As toddlers they are overactive and oppositional. Later on they are irritable, inattentive and low on pleasure," he added. Funded by the National Institute of Mental Health, the research also supports a 2006 report by the U.S. Surgeon General that found passive smoke exposure pos...

Preterm Labor Drug Causes More Side Effects

...called tocolytics, are thought to work by relaxing overactive uterine muscles and halting ongoing cervical changes that may lead to delivery. But it's not been clear if one is better than the others. Force of habit has dictated the use of magnesium sulfate by many physicians in the absence of a compelling reaso...

Pain and Intensity Of Post-stroke Spasticity Decreased by Botox Treatment

...and/or thumbs flexor of the affected limb to block overactive nerve impulses that trigger excessive muscle contractions. Patients were assessed every six weeks for one year. Patients demonstrated a significant reduction in pain and excessive muscle tone at each follow-up. In addition, average pain intensity was...

Stimulating the Ankle Can Help Patients With Overactive Bladder

...nd help for this embarrassing problem. It's called overactive bladder (OAB) and it's characterized by a sudden ...eurostimulation for urological conditions, such as overactive bladder and urge incontinence," says Jenelle Foote, MD, an Emory Crawford Long Hospital urologist. "...

Women Urged to Be Wary of Ads Promoting Unwanted Drugs

...ty disorder, heartburn, restless leg syndrome, and overactive bladder are all examples of symptoms or normal physiological events that are now presented to consumers as being in need of long-term drug treatment. Prescription drugs used to be advertised mainly in medical journals aimed at health care provider...

Sugar Supplement may Harbour Cure for Immune Diseases

...e found that a sugar supplement may help treat the overactive immune cells that are responsible for autoimmune diseases, such as multiple sclerosis (MS) and type 1 diabetes, and stop them attacking the body's tissues. Lead researcher Michael Demetriou says that their finding is based on a study of N-acetylgl...

Breast Cancer Drug Curbs Heart Disease.

...ely one in four women with breast cancer have this overactive gene, which is associated with increased cancer recurrence and worse outcomes. Lapatinib was approved earlier in March for use in women who have not responded to trastuzumab therapy. Trastuzumab revolutionized the treatment of HER2-positive breast ...

A New Drug That Could Help Alcoholics

... of Neuroscience, show that the CRF system becomes overactive in animals with a history of alcohol dependence, increasing the risk of relapse. The researchers say MTIP can be given orally, and reaches the brain in sufficient amounts to block more than 90% of CRF receptors. But MTIP does not accumulate in othe...

RNAi Shows Promise in Gene Therapy

...sed as gene therapy, RNAi turns off genes that are overactive in such diseases as cancer or macular degeneration, or disables genes needed by an invading virus. With key genes shut off, viruses such as hepatitis or HIV are unable to multiply and cause disease. In early RNAi experiments, researchers saw some h...

Europeans Developing First-Ever Dengue Fever Vaccine

...bitor was introduced into the culture blocking the overactive metalloproteinase, natural permeability was restored. Their hypotheses concerning metalloproteinase were again supported through in vivo testing in mice. The results uncovered by the European-led international team shed new light on Dengue’s pathol...

Gene Therapy May Be the Solution for Erectile Dysfunction

...y works on smooth muscle, it is also promising for overactive bladder disease,” adds Dr. Melman. Dr. Melman, with George Christ, PhD, developed the process for ion channel therapy at the Albert Einstein College of Medicine, which owns the patents. Montefiore is the academic medical center for Einstein. Einste...

Combination Therapy More Effective for Treating Lower Urinary Tract Symptoms

Men with overactive bladder and lower urinary tract symptoms who recei...en 40 years or older have symptoms consistent with overactive bladder, according to background information in the article. Lower urinary tract symptoms include ur...

Botox Shots May Even Help In Reducing Knee Osteoarthritis Pain

...t from treatment of headache, ringing in the ears, overactive bladder, diabetic nerve pain and much more. These studies have got the approval of FDA. Researcher Maren Mahowald, M.D., rheumatology section chief at the Minneapolis Veteran's Affairs Medical Center and professor of medicine at the University of ...

Women in the throes of depression portray differences in brain chemistry

...searchers also found that the mu-opioid system was overactive in women with depression, even at baseline, when they weren't being asked to recall sad memories. During the "sadness challenge", the non-depressed women did not show any activation of their mu-opioid system, but the depressed women had a significa...

Psoriasis raises risk for heart attack

...bout 3% of adults.According to many scientists, an overactive immune system is responsible for this condition that accelerates the skin cell growth cycle, causing the skin cells to shed too rapidly and form visible, red plaques. Some patients develop a type of arthritis causing stiffness and swelling in the j...

Bladder Control following Weight loss in women with Prediabetes

...ecause urge incontinence is more closely linked to overactive nerves that control the bladder, causing occasional triggering of inappropriate contractions. It has been estimated that more than 13 million people in the United States, mostly middle-aged and older women, experience loss of bladder control. Over...

Patients With Major Depression Have An Overstated Inflammatory response to Stress

...cine, had stated in their findings that just as an overactive inflammatory response might contribute to a number of medical disorders as well as to depression, the increased inflammatory responses to stress in depressed patients might also act as a link between depression and other diseases, including heart dis...

"Miracle" Cancer Drug Gleevec Can be Toxic to the Heart

...a hybrid BCR-ABL enzyme that is always active. The overactive BCR-ABL, in turn, drives the excessive proliferation of white blood cells that is the hallmark of CML. According to Dr. Force, 10 patients taking Gleevec at the University of Texas’ M.D. Anderson Cancer Center in Houston developed fairly severe hea...

Researchers Have Linked Rett Syndrome to Mitochondrial Gene

...ession of this gene was solely responsible for the overactive mitochondria. And the data said it's likely to be," says Bird. He adds that additional experiments are needed to link the mitochondrial abnormalities to the symptoms found in the mutant mice. The researchers also caution that similar defects need to ...

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