Novel drug holds promise for treatment of Rheumatoid Arthritis
...essful completion of Phase II clinical trials of a novel drug called dnaJP1 for treatment of osteoarthritis... against other infectious diseases or cancer. The novel drug is a peptide derived from a naturally occurring protein, dnaJ, which generates inflammation in ...HIIP- A Novel Inhaled Insulin Delivery System As An Alternative To Injectable Insulin Therapy
... Care, evaluated the key performance features of a novel inhaled insulin delivery system -- human insulin inhalation powder (HIIP) -- based on AIR particle technology and its relative biopotency compared with subcutaneous (SC) insulin lispro. The researchers enrolled 20 healthy, nonsmoking, male or femal...A Novel Method For Measuring Interstitial Fluid Pressure In Cancer Tissues
...liable measurement of IFP in tumor tissues. This novel procedure, using a polyurethane transducer-tipped catheter (Millar), allows reliable measurement of interstitial fluid pressure (IFP) in cancer tissues. Before and after each use, the transducer is calibrated at 37°C by a water column. After calibrat...UV- Light Tanning As A Type Of Substance-Related Disorder
...itively expose themselves to UVL to tan may have a novel type of UVL substance-related disorder....Age-Dependent Alterations Not Specific For Alzheimers Disease
...Both of these functions are preserved in AD. The novel findings from this study, which appears in the journal Microvascular Research (available online 14 October 2005) are that the forehead flow motion displays an age-dependent pattern. Also, under resting conditions, low-frequency oscillation in the for...Protein Carbonyl Level Causes Oxidative Protein Damage In Diabetics
...nt. The authors propose plasma PCO derivate as a novel specific marker for oxidative protein damage. Medindia on Diabetes: Diabetes is a group of diseases with one thing in common - a problem with insulin. The problem could be that your body doesn't make any insulin, doesn't make enough insulin or ...Novel Technique For Targeting Small-Cell Lung Cancer
...n. In a recent work, researchers from Israel used novel backbone cyclic peptides, which function as Somato...binding, tumor-targeting vectors. They synthesized novel somatostatin analogs, based on backbone cyclic peptides, and conjugated them with fluorescent agents...A New Initiative To Fight Childhood Obesity
In a novel initiative to combat the spread of childhood obesity, The Alliance for a Healthier Generation, a joint initiative// of the William J. Clinton Foundation and the American Heart Association, has announced that it has entered into a partnership with Nic...The potent anti-leukemia activity of Berbamine
.... The authors conclude that berbamine might be a novel bcr/abl inhibitor with potent anti-leukemia activity, and that the potency of berbamine against both Gleevec-sensitive and -resistant Ph+ leukemia cells, and its distinct mechanism of anti-leukemia activity warrant further investigation of berbamine ...Bortezomib for salvage therapy against progressive myeloma
...b (Velcade, formerly PS-341, Millennium, USA) is a novel first-class agent that inhibits the proteasome, a // multicatalytic cellular enzyme whose activity entails several molecular mechanisms, including, in particular, the NF-kB pathway. Currently, bortezomib, alone or in combination with dexamethasone...Chronic Exposure To Benzene May Result In Dysplasia
...ism remains unknown. This paper describes a novel form of bone marrow dysplasia in 23 workers exposed to high concentrations of benzene. Distinguishing features of benzene-induced dysplasia include: marked dyserythropoiesis, eosinophilic dysplasia and abnormal cytoplasmic granulation of neut...Exercise Can Strenghten Knee Cartilage
...e of Arthritis & Rheumatism, describe the use of a novel MRI technique to determine the impact of moderate exercise on the knee cartilage of subjects at high risk for developing OA. The main aim of the study was to evaluate the effects of moderate exercise on glycosaminoglycan content in knee cartilage in ...Protein Markers for Identification of Brain Tumor
... new treatment approach and the EphA2 represents a novel target for the development of molecular therapeuti...ebinski has been focusing on identification of new novel molecular markers, which helps in diagnosis of cancer in an early stage. Source: Newwise....Survey finds that discussion with family very crucial in organ donation decision
The novel idea of organ transplantation continues to entice the imagination of successive generations with significant advancements being achieved every day. The worldwide demand for human organs has prompted researchers to look into the concept of organ donat...New spinal surgery technique developed by UCSF Surgeon
...erable can now be handled with ease. Thanks to the novel technique developed by surgeons at the USCF instit...ial pedicle screws. The neurosurgeon behind this novel innovation specializes in spinal reconstructive surgery for trauma, tumors and degenerative disease,...Ruboxistaurin As A Novel Treatment For Diabetic Nephropathy
...tes Care, establishes Ruboxistaurin as a promising novel treatment that may improve upon established therap...blished therapies. Therefore, treatments targeting novel pathogenic mechanisms may be beneficial. Studies have shown an important role for prote...New Model for understanding Tumor Metastasis
... and signaling pathways that could be targeted for novel therapeutic strategies to inhibit the spread of melanoma," Hendrix said. Metastatic cancer cells are characterized by increased tumor cell invasion and migration, as well as an undifferentiated, or "plastic," nature. The Hendrix lab has hypothesi...Novel Actemra monotherapy in treating patients with early aggressive rheumatoid arthritis
...genetically identical group of cells, a clone. The novel mechanism of action of the antibody can eventually pave way for a new therapeutic option for the treatment of RA. Nearly 306 patients with early aggressive rheumatoid patients were taken up for the study and were randomized to receive either Actemra ...A Step Towards Unraveling The Schizophrenia And Depression Mystery
...This new research has the potential for developing novel ways of diagnosing and treating this debilitating disease." Peter Hutson, the Neuroscience Research Centre, Merck Sharp & Dohme, said: "Mental illness remains a scourge of society. Our insights into the important role that the proteins PDE4B and DI......nd make for healthier food and social habits.” The novel finding of the study was that a healthy maternal attitude to family eating and diet was more important than the frequency of shared meals. The sample size was 3795 mothers and their teenagers, which was taken in Brisbane when the teenagers were at a...