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Novel "CYCLOSPORINE CAPSULE FORMULATION" to be launched

Cyclosporine has revolutionised the transplantation scene in the last 20 years by helping with immunosuppresion. Novartis have so far had the patent for the drug and enjoyed the profits. The cost of the medicine is prohibitively expensive.However in the past few years other pharma companies have been allowed to manufacture the drug giving Novartis a competetion. The current tablet size are big an...

Novartis files application with FDA for Zometa

Novartis Pharmaceuticals has submitted an application to the Food and Drug Administration, seeking marketing authorization for Zometa in the treatment of bone complications associated with a broad range of tumor types. These include prostate and lung cancer, for which no bisphosphonate therapy is currently approved. The spread of cancerous cells from the original tumor to the bone, can lead to se...

A novel augmentation

Scientists from Japan have augmented the cells of frog eyes and ears in a test tube, in the erstwhile step towards grow-your-own organs.The mode uses special cells taken from frog embryos called stem cells. These have the potential to develop into any specific type of cell in the frog's body - heart, skin, muscle and so on.// ....The major technique used by the team at Tokyo University is the us...

Novel biopsy technique for prostate cancer

Recently a more extensive biopsy detecting technique for prostate cancers has been found out by researchers.// This is very effective than the traditional examination. In the traditional exam for prostate cancer, the doctor takes six tissue samples from the prostate gland. .. At Ohio State University, researchers said that it is better to take more samples. ..Dr.Robert Bahnson and his team, call...

Genetic innovation

Over 4cm of men's height is due to the combination of just two genes, according to a new study undertaken at the University of Melbourne.The research, published in the Journal of Clinical Endocrinology and Metabolism this week,// identifies one gene on chromosome 15 and one on the Y chromosome as contributors to height in men. These genes may also help explain why men are taller than women. ...."...

Novel computer model for breast cancer

A worldly-wise computer model can forecast which breast cancers will spread and so need aggressive treatment. Researchers at University of Hopkins, have developed a neural network system - where a computer is taught to spot patterns //- in combination with fuzzy logic, a way of modeling the uncertainty of natural language. The result is a model which can scrutinize images of breast cancer cells,...

Novel research on liver cancer

A new study contributes to the findings of liver cancer. Investigators at Johns Hopkins University School of Medicine report findings on a potential new treatment for this ghastly cancer. In the study, researchers injected a compound called 3-bromopyruvate// directly into the artery that leads to the cancerous tumor. They say it did not adversely affect the healthy portion of the liver or surroun...

Innovative device aids in advanced heart failure

A mesh jacket positioned around the heart improves function in patients with advanced heart failure. Researchers at the University of New York felt that in heart failure, the heart enlarges and is unable to effectively pump blood around the body.// Commonly, the heart valves are damaged too. Heart failure is a progressive condition, with no cure other than a transplant - although it can be manage...

Zometa [Novartis Drug] For Treatment Of Paget’s Diseas

Results of the clinical study carried out by Professor Ian Reed and his team from the University of Auckland in New Zealand has found that the drug Zometa manufactured by Novartis treats Paget’s disease// far better than the drug Actonel produced by Procter and Gamble. ....Paget's disease is a condition in which the bones breaks or becomes weak faster than the normal and the new bone replacement...

Novel Test For Early Detection Of Gullet Cancer

Detecting cancer of the esophagus could be as simple as swallowing a spongy pill with a string attached to it. Thanks to the fervent efforts of Cambridge University researchers // that can detect more than 7,000 such cancers that occur in UK every year. It is the ninth most commonly occurring tumor in the Britain. ....Once in the windpipe, the pill is pulled out, gently scraping cells from the g...

Novel Treatment to Cure People with Learning Disabilities

Wynford Dore a British millionaire currently living in Australia claims to have discovered a novel way of curing children suffering from the worst form of attention deficit hyperactivity disorder (ADHD). //This novel method, space-age technology is usually used for testing astronauts returning from space. But it can also be used by the doctors to cure ADHD patients by rebalancing their brains. .....

Novel Approach to Identify Protein Links with Genetic Disorder

Researchers at Johns Hopkins University and the Institute of Bioinformatics in Bangalore, India, created a database of more than 25,000 protein-protein interactions// . It is the first large-scale analysis of protein interactions in human cells. This has helped in the scientists to identify new genes that cause genetic diseases. ..This database is the most detailed human interactome developed so...

Novel way to fight cancer

Scientists feel that they have found a innovative way to fight deadly cancers: increase a patient's immune cells in the laboratory to recognize and fight the patient's own tumor, then inject the cells back into the body and let them go to work.// ....Known as adoptive transfer, the experimental technique involves the body's T cells, which are responsible for finding and attacking foreign cells th...

Novel test for bowel cancer

Researchers have developed a rapid and infallible test for bowel cancer based upon a molecule found only in cancer cells. We already know that bowel cancer is highly curable if caught early. Screening with sigmoidoscopy - an internal exam// of the bowel can reduce the incidence of the disease. Now researchers in the find that a reliable test can also be done on samples of feces. ....The bowel sh...

Canine Painkiller unveiled by Novartis

Novartis received approval from the Food and Drug Administration to begin marketing Deramaxx, a canine painkiller, which will be used to relieve post-operative pain in dogs. This drug being produced by a Novartis facility at Puerto Rico //is the result of a development project undertaken by Novartis Animal Health that was run for several years at veterinary clinics, colleges and its manufacturing...

Novel Anti-Neutrophilic Effect produced by Salmeterol in mild asthma patients

A recent three-way crossover study over six weeks by clinicians at the National Heart and Lung Institute, Royal Brompton Hospital, London has shown that Salmeterol produced a novel anti-neutrophilic effect among patients with mild asthma. The study was prompted by the long standing argument about the effects of long-acting beta2-adrenergic receptor agonists, such as salmeterol, on inflammation. T...

Novel Therapy for Chronic Problem

Doctors at Mayo Clinic in Rochester, Minn., say they have found a new treatment for a fast-growing disease. Eosinophilic esophagitis (EE) is an allergic inflammatory reaction of the esophagus. The symptoms for EE mimic gastroesophageal reflux disease (GERD). New research shows a topical corticosteroid therapy is effective for patients with EE. ....EE is caused by the presence of high levels of eo...

Innovative footwear may prevent fall in elderly

A new device may be able to stop the geriatric population from falling and hurting themselves from being //unable to maintain their balance... ..The device is called Yaktrax Walker. This is plastic netting like structure that conforms to the footwear and helps the people wearing them in maintaining a stable walk that will prevent falls. ....Researchers for the device had asked the participants t...

Gene enchances radiation therapy - A novel approach to fight cancer

In the era of fighting battle against cancer, researchers of Virginia have come out with a novel approach to execute the destiny. Radiation therapy is used to treat many types of cancer. An experimental form of gene therapy makes cancer cells more susceptible to radiation therapy. .. .. Although radiation kills cancer cells, it has unwanted side effects that could counter its positive effe...

Innovative yeast genome may handle Cancer Clues

According to scientists mapping of have mapped all the genes in a second type of yeast that they hope will provide new insights into basic cell biology and the development of cancer.A team of international scientists led by Nobel medicine laureate Sir Paul Nurse of the charity Cancer Research UK has sequenced the genome of fission yeast, a cousin of the brewer's yeast whose genome// was mapped. ....

Glivec the hot cancer drug from Novartis

Novartis is the world's sixth-largest drugmaker (by sales). ..Novartis was formed after merger of two Swiss companies, Sandoz Ltd. and Ciba-Geigy."Novartis ..is emerging as one of the premier powerhouses in the global pharmaceuticals industry," ..says Richard R. Stover, senior analyst with brokerage Natexis Bleichroeder Inc. ..in New York. The new cancer drug, Glivec's success led to Novartis re...

Blood Sugar Kept In Control By Novel Protein

Scientists claim that a new protein identified can help in the treatment of metabolic disorders such as type 2 diabetes. The protein has already shown promising results by extending lifespan in yeast, worms and flies // and is known to keep blood sugar under control in mice. ..Experiments have demonstrated that mice with an excess of the protein Sirt1 in cells of the pancreas have improved glucos...

Novel antibiotic dressing developed for improved wound healing

Hospital acquired infections, remains a significant health issue to be tackled and the number of mortality as a result of this keeps increasing every year. Antibiotic-resistant // bacteria, such as methicillin-resistant staphylococcus aureus and vancomycin-resistant enterococci, cause about 70 percent of such infections... ..In an attempt to reduce the incidence of such events, researchers have n...

Novartis MS Drug Shows Promising Results

Data from the extension of a Phase II study to 12 months confirm the significant effects of FTY720, a novel oral medication//, for the treatment of patients with relapsing multiple sclerosis (MS). ....The data, presented at the ECTRIMS/ACTRIMS meeting in Thessalonica, Greece, showed that both patient groups taking FTY720 (1.25 mg and 5 mg) who had experienced a reduction in their annualized rela...

United Kingdom Is Lagging In Novelty In The Field Of Pharmaceuticals

United Kingdom is lagging in innovation, as shown by the market share of new medicines in various countries, including primary care and hospital markets. Reports from various sources prove that Europe has shown very low growth in the field of pharmaceuticals and hospital care//. .. ..Europe has a new plan in order to counter the worsening competitive position of its biopharmaceutical enterprises....

Novel drug holds promise for treatment of Rheumatoid Arthritis

The successful completion of Phase II clinical trials of a novel drug called dnaJP1 for treatment of osteoarthritis that works without suppressing the immune system has been announced by Researchers at the University of California//. ..Rheumatoid arthritis is a chronic, painful disease affecting millions worldwide. It is thrice more common in women in men and affects people of any age. It strike...

HIIP- A Novel Inhaled Insulin Delivery System As An Alternative To Injectable Insulin Therapy

The disease burden of diabetes continues to grow and currently affects more that 18 million Americans and their families. These data emphasize a need for alternative diabetes therapies with earlier more physiologic use of insulin.// ..The delivery of insulin by the lung may provide an attractive alternative for many patients with diabetes. However, alternative insulin delivery systems must meet...

A Novel Method For Measuring Interstitial Fluid Pressure In Cancer Tissues

In normal subcutaneous tissue, the interstitial fluid pressure (IFP) is negative, and so, when the subcutaneous tissue of an animal is exposed, fluid does not seep out. //By contrast, IFP is often increased in tumor tissue and forms a barrier against efficient drug delivery into the tumor. ..Many anticancer drugs and antibodies used for treating patients with cancer are transported from the circ...

Novel Strategy To Combat Alzheimer’s Disease

Alzheimer’s disease (AD), characterized by progressive memory loss, decline in language skills and other cognitive impairments, has been a major threat to ageing population.// ..A recent paper in the October issue of FEBS Letters, reviews the different strategies in drug discovery. Hong-Yu Zhang, the author of the study, muses that the success of the present one-drug-one-target strategy in drug...

A Novel Method Of Detection Of High Nuclear Grade Localized Renal Cell Carcinoma

Elective nephron-sparing surgery (NSS) is considered appropriate for small renal cell carcinoma (RCC) tumors; however, it is still difficult to detect high nuclear grade RCC preoperatively. // ..Although no specific tumor markers have been identified for RCC, immunosuppressive acidic protein (IAP) is a variable predictor of lymph node and distant metastasis in patients with RCC. At present it is...

Novel Technique For Targeting Small-Cell Lung Cancer

Small-cell lung cancer (SCLC), accounting for about 20% of all lung cancers, is a particularly aggressive form of malignancy// with about 80% of cases presenting in advanced stages. Early, accurate detection of SCLC, before it becomes systemic, is essential for successful treatment. ..Tumor targeting with specific carriers is a promising approach that can significantly enhance the diagnostic powe...

Novel protein found to enhance effect of Vitamin E and suppress prostate cancer

Researchers have identified a protein that disrupts an important signaling pathway in prostate cancer cells, thereby suppressing the tumor. The protein also enhances the retention of Vitamin E // that limits the proliferation of cancer cells. ..The researchers of the present study are the first to describe the role of a protein known as alpha tocopherol associated protein or TAP in prostate canc...

Kasturba Medical College Organizes 'CME- Orth 2005' From 4th To 6th November

A Continuing Medical Education Programme 'CME- Orth 2005' is being organized by the Orthopedics department of Kasturba Hospital, Manipal from November 4 to 6. The programme includes course lectures,// clinical case discussions and demonstration of orthosis, prosthesis and radiological techniques. .. ..The programme was inaugurated by Dr. R S P Rao, Dean of Kasturba Medical College. Dr D P Saras...

A Novel System For Clinical Banking Of Umbilical Cord Blood

Researchers from Italy have designed a closed circuit, where Umbilical cord blood (UCB) collection and RBC depletion are performed, in order to reduce the contamination risk and to speed the nucleated cell separation//. ..Their findings appear in the journal Blood Cells, Molecules, and Diseases (available online 19 August 2005)..Umbilical cord blood is a source of hematopoietic progenitor cells...

Novel Technique For Management Of Inverted Papilloma Of Frontal Sinus

According to new research, large sinus tumors can be removed through the nose using endoscopy rather than having to make large incisions in the face//. ..With this approach, doctors use tiny scopes and cameras to enter the nose and remove the tumor with a device that pulverizes and suctions. At points where the tumor adheres to the sinus lining, the lining is removed and a diamond drill is used...

Ruboxistaurin As A Novel Treatment For Diabetic Nephropathy

Recent research, which appears in the current issue of Diabetes Care, establishes Ruboxistaurin as a promising novel treatment that may improve upon established therapies for diabetic nephropathy//. .. Nephropathy is known to develop in 40% of people with type 2 diabetes and is the leading cause of end-stage renal disease in the U.S. and the developed world. .. Many persons w...

Low turnover by Diabetics for free annual checkup

New Zealand President Murray Dear is not happy with the amount of diabetic patients signing up for annual check up. The statistics show that only 60% of diabetic patients // had signed up for free annual check up for diabetics, which is a state, funded program. .. ..The President is not happy with the outcome and as said to the people that diabetics is not properly monitored it could lead to com...

Novel Biological Pacemaker Under Construction for Weak Hearts

Johns Hopkins scientists have developed a natural or rather biological pacemaker by fusing connective tissue cells of guinea pigs with heart muscle cells. The newly developed pacemaker can fire on it’s own and regulate the rhythm // of the heart in a more physiological way... ..Two sets of tiny electroactive 'pacing cells' (SA node) give rise to the heart’s normal rhythm by stimulating other cell...

Novel Actemra monotherapy in treating patients with early aggressive rheumatoid arthritis

The first Phase III study involving the use of Actemra in the treatment of rheumatoid arthritis has revealed that it is superior to conventional treatment modality that uses disease modifying anti-rheumatic drugs (DMARDs to inhibit // joint destruction. It has also been found to provide symptomatic relief and improve sensation of pain. .. ..Rheumatoid arthritis is a debilitating autoimmune diseas...

Delhi To Host International Women’s Congress From Nov 2

Delhi will play host to 800 women from 55 countries who will be the fourth International Congress on Women from November 27. // ..The four-day international congress titled "WWH-2005" (women, work and health) will be held for the first time in South Asia. The earlier meetings were held in Barcelona (1996), Rio de Janeiro (1999) and Stockholm (2002)... ..Among its main objectives, the congress aim...
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