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Tag: "notch1" at medical news

Mutations in NOTCH1 cause an early developmental defect in the aortic valve

Dr. Srivastava and his colleagues of UT Southwestern Medical Center of Dallas// discovered that the mutation in a gene NOTCH1 is responsible for aortic valve disease. Aortic valve disease is a common heart birth defect which causes adult heart disease. ..The study was done in five generations of a Dallas family; the researchers studied the DNA mutations in all the 11 members of the family who we...
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