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Tag: "mutating" at medical news

Genome Annotation by Mutation

...e developed a faster, less expensive technique for mutating those large, non-gene stretches of DNA. Genes acco...nces. The new method is a faster, cheaper way of mutating DNA, costing $200 to create each mouse with a mutant gene or other DNA sequence, although the saving...

Theory of How HIV Attacks is Wrong: Study

...tion, the authors said. "The virus is constantly mutating and there may be selection - in a Darwinian sense -- over time for 'fitter' mutants of the virus in an infected person," said lead author Andrew Yates of Emory University in Atlanta, Georgia. "There are several ways the virus could become fitter - ...

Bird Flu Risk Still Running High in Egypt, Indonesia, WHO Says

...ypt and Indonesia where the risk of the H5N1 virus mutating into a major human threat remains high, the UN health agency said Wednesday. "In the 15 or so countries in Asia, Eastern Europe and the Middle East where the H5N1 virus was introduced during the past six months, it was rapidly detected and elimina...

Highly Effective Method for Screening Drug-resistant Forms of HIV Developed

...rious stages in its replication, but still quickly mutating forms of HIV can complicate treatment outcomes. The researchers reckon that nearly 50 per cent of individuals being treated for HIV in the US carry drug-resistant forms of HIV, which was either caused by mutations in the virus in response to drug ...

Malfunction of Gene Causes Schizophrenia, Depression

... researchers sought to explore the consequences of mutating a gene called "Disrupted in schizophrenia 1" (DISC1), which was found to be associated with schizophrenia, bipolar disorder and major depression. The researchers' theory was that different mutant variations of DISC1 might have different pathologica...

Mutant Parasites, Unable to Infect Hosts, Highlight Virulence Genes

...irulence, they took the reverse approach, randomly mutating individual genes in the parasites, then looking to see which of the mutant parasites could no longer infect host brains. "Let's let the parasite tell us what's important," Knoll says. The broad approach helped them uncover dozens of genes - many of...

Malfunction of Gene Causes Schizophrenia, Depression

... researchers sought to explore the consequences of mutating a gene called "Disrupted in schizophrenia 1" (DISC1), which was found to be associated with schizophrenia, bipolar disorder and major depression. The researchers' theory was that different mutant variations of DISC1 might have different pathologica...

Indonesia Struggles Against Bird Flu and the Drug Industry as Well

...keeping experts from monitoring whether the bug is mutating into a dangerous form that could potentially spark the next pandemic that kills millions. But government officials continue to hold their ground in a showdown with WHO - despite agreeing last month to resume sending samples. They are using the viru...

Bird Flu Vaccine - Indonesia Attracts WHO Attention

... to be abreast with the genetic composition of the mutating virus. The WHO whets this information and creates a seed strain for pharmaceutical companies to produce vaccines. This process went on unhindered till Indonesia, the country faced with virulent bird flu attacks, withdrew from the prior arrangement ...

Genetic Pathways to Curable and Incurable Forms of Pancreatic Cancer Identified

...c cancer oncogene called Kras and then selectively mutating tumor-suppressor genes such as p53, p16 and Dpc4 in different combinations. In the mouse model, which Hingorani first developed while at the University of Pennsylvania, the combination of Kras and p53 led to the more deadly form of pancreatic duct...

MSU Research Strengthens Link Between Smoking, Pancreatic Cancer

..., multimechanism process of carcinogenesis, not by mutating the stem cell, but by triggering the stem cell that’s been previously mutated to proliferate,” said Trosko, a professor of pediatrics and human development. “This finding has major implications, including the possibility that dietary intervention mig...

HIV Spread May Be Arrested By A New Compound

...pound appears to work differently and counters the mutating capability of HIV virus. This team plans to go further deep into this research focusing on the molecular mechanisms of 2-5AN6B and the remedial measures for HIV infection. JYT...

Not Just ‘Bird’ Flu Anymore- Avian Influenza Strikes Cas

...s infected, that could be a sign that the virus is mutating to adapt to mammalian hosts. If they are adapting to mammals, they could be on the way to adapting to humans, to become a human virus.” In another case, Gusti Ngurah Mahardika, a virologist at Udayana University, surveyed pigs and domestic animals ...

Sugars in Liver Found to Clear Fats from the Bloodstream

...ryo or death shortly after birth. “By selectively mutating a single tissue in mice, in this case the liver, we avoided a lethal effect,” said Esko. In the lab, the researchers combined the heparan sulfate mutation with a mutation in the LDL receptor, which has long known to be responsible for clearing choles...

Young Women Beware Of LAM

... caused the cell proliferation and identifying the mutating gene that was responsible. Next, Krymskaya’s lab at the University of Pennsylvania was responsible for the breakthrough step of discovering the function of the gene that caused the cell malfunction, paving the way for a potential treatment utilizing ...

Study Unveils West Nile Virus Immune Evasion, Points to Vaccine Development

...in could be used as a basis for a vaccine, perhaps mutating North American strains so they no longer disrupt immune signaling. The remaining key is figuring out the exact mechanics of how the strains block signaling, a project Dr. Gale’s team is already at work on. Fortunately, North American strains are ex...

Virus Can Mutate lethally With Help Of Carbohydrates

...on of the proteins on the outer shell of the virus mutating to get a more lethal grip on a cell's sugary coat of carbohydrates, or glycans, as they were studying the Minute Virus of Mice, or MVM. They found that that a single strain of the virus, MVMp is actually a harmless strain that causes no ill-effects e...

Breakthrough Announced in Development of Bird flu drug

...y that so far no evidence exists that the virus is mutating towards a state where it is transmissible among humans, although this could happen at any time. About 60 percent of those infected with the deadly H5N1 virus have died. The best known drugs to fight the H5N1 infection in humans are zanamivir known...

Drug Firms Competing to Produce Cheap and Effective bird flu vaccine

...nfected with the disease. Fears exist of the virus mutating as the disease spreads within families or close-knit communities. Although it is still not certain that any vaccine would be effective against H5N1 in humans against new pandemic strains it is expected to provide some immunity. Nevertheless, this n...

Dutch chemical group Akzo Nobel Develops A New Bird Flu Vaccine

...ain low-pathogenicity virus strains are capable of mutating into high-pathogenicity viruses. They explained this vaccine acts by attacking the problem at the root level, and therefore prevents the spread and advancement of the disease. Toon Wilderbeek, Akzo's executive in charge of pharmaceuticals also expl...

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