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Tag: "mutant" at medical news

Red haired withstand to pain more than blond headed

...University in Montreal, Canada. Mogil identified a mutant version of a gene called melanocortin-1 (Mc1r) that is linked to ginger hair and fair skin and makes women, although not men, more resistant to pai....

Gastrin, Much More Than The Weight Management Hormone

... said. The experiments compared normal mice with mutant mice whose gastrin production capability was removed through genetic engineering. Researchers observed that if gastrin is removed in mice with normal diet, the mice become obese. So, the team set out to find out why removing gastrin made mice fat. Up...

Gene in Melanomas

...y of Cancers.// Seventy four per cent of the Cdk4 mutant mice developed melanomas after being exposed to carcinogenic treatment, the authors report.The finding gives a better understanding of the body processes underlying melanoma, which could eventually lead to better treatments. The Cdk4 gene has been k...

Gene enchances radiation therapy - A novel approach to fight cancer

...archers in their experiment injected the mice with mutant form of EGFR, called EGFR-CD533 that prevents the ...ound that tumor cells in the mice treated with the mutant gene were 46% less likely to survive than those in untreated mice. The study shows that disrupting...

Possibility Of Treatment For Permanent Hearing Loss

...nt negative mechanism -- when a single copy of the mutant gene is sufficient to cause disease because the pr... loss. Then they had simultaneously introduced the mutant gene and a short piece of interfering RNA specifically designed to silence the gene. Standard hearin...

Hangovers: why some people suffer and some don’

Japanese study had identified a mutant form of the enzyme aldehyde dehydrogenase// (ALDH)...lar problems. People from East Asia often have a mutant allele called ALDH2*2 and an inactive ALDH that prevents them from drinking heavily because of feeli...

Emergence Of New Gene Scanning Technology In Disease Research

...t foundation and Department of Health identified a mutant gene causing high, moderate cholesterol levels among 10,000 middle aged individuals. Through this technique one can identify rare genetic mutation in a population and identify gene level changes says professor Day. Although this research is at still...

Gene is related to premature ageing disease

...o reverse the symptoms. The process will eliminate mutant LMNA mRNA and lamin A protein using splicing correction to the activated cryptic splice site. On doing this, the HGPS fibroblasts become like normal cell nuclei. This helps in the proper _expression of the several deregulated genes that cause the dis...

Mutant sperm beat out healthy brethren in study

According to Researchers Men produce more mutant sperm as they get older //and they found to their surprise that some of these mutations give the sperm an edge. The deformed sperm increase the risk of disease in the men's offspring, but nonetheless are likely to beat out their healthy counterparts...

Missing Protein In Cancer Development

...somehow gets disrupted, the resulting cells become mutant versions of the original cell. The researchers studied mouse cells that lacked E2F3 as well as cells that contained the protein. The cells were grown in culture dishes in a laboratory. The researchers were particularly interested in the behavior of c...

Special proteins to fight TB identified

...and Medicine in London, and colleagues developed a mutant form of the TB bacterium that produced extra heat-...ble to cause an acute infection in mice. But this mutant form of TB did not cause a chronic infection unlike ordinary TB bacteria. It is possible that high ...

Anthrax vaccine produced

...by Dr Rakesh Bhatnagar. It is made up of harmless mutant forms of three key proteins that together make the toxin that does the damage to humans infected with anthrax. The protective antigen, lethal factor and edema factor. Individually, the proteins are non-toxic, but in combination they can be deadly. Th...

Genes for Vision discovered

...ptors?” she said. A little more than half of the mutant genes for degenerative diseases of the retina had been identified when Cepko began his study. Using a computer program that compares snippets of genetic material taken from mouse retinal tissue with a huge genetic database from the mouse and human ge...

Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese

...ngton's] was due to a toxic activity caused by the mutant protein. Here we show that there is a loss of normal function" Dr. Elena Cattaneo said. "There must be a cure for this disease," she added, "and there must be one very soon."...

Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase

...ngton's] was due to a toxic activity caused by the mutant protein. Here we show that there is a loss of normal function" Dr. Elena Cattaneo said. "There must be a cure for this disease," she added, "and there must be one very soon."...

Special proteins to fight TB identified

...and Medicine in London, and colleagues developed a mutant form of the TB bacterium that produced extra heat-...ble to cause an acute infection in mice. But this mutant form of TB did not cause a chronic infection unlike ordinary TB bacteria. It is possible that high ...

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