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Tag: "monotherapy" at medical news

ZD1839 Proves Effective - A Breakthrough in fighting Lung Cancer

...ith advanced non-small cell lung cancer (NSCLC) as monotherapy and in combination with standard chemotherapy agents after segmental scrutinization in two different studies. Vincent Miller, MD, of Memorial Sloan-Kettering Cancer Center in New York and the principal investigator of the first study said, "It is ho...

Cure for osteoporosis in prostate cancer patients

...idal synthetic oestrogen should be considered as a monotherapy in men who require long-term antiandrogen therapy.// Over 18 months the researchers evaluated 54 patients with clinically localised prostate cancer and 24 with benign prostatic hyperplasia. Those with prostate cancer were either treated with externa...

Novel Actemra monotherapy in treating patients with early aggressive rheumatoid arthritis

...y and were randomized to receive either Actemra as monotherapy or traditional treatment. Actemra was administered...rly, aggressive disease. The tolerability of the monotherapy was comparatively much higher in the Actemra group. Although there was a slight increase in the chol...

Combination Therapy With ENBREL And Methotrexate Found Effective In RA Treatment

...ound to be superior when compared to either of the monotherapy forms. A comparison of the combination therapy, ENBREL monotherapy and methotrexate monotherapy revealed that ENBREL monotherapy had significant results when compared ...

Global Fund Policy Encouraging Drug Resistance

... Global Fund's compliance list and boost their own monotherapy sales. Although several countries have also agreed...endorsement for drugs and is used for marketing by monotherapy manufacturers. ...

Combination Drug Therapy For Hypertension

...lighted the importance of multiple drug therapy to monotherapy in diabetics with hypertension. According to Neu...ients. According to Flack, some doctors practice monotherapy and do not add/change the drug even in patients who continue to have high blood pressure. He furth...

Enbrel Joins with Methotrexate to Cure Rheumatoid Arthritis

... and methotrexate. Subjects receiving methotrexate monotherapy during the 3-year double-blind TEMPO trial were sw...d methotrexate (n = 55). Subjects receiving ENBREL monotherapy during the 3-year double-blind TEMPO trial were switched to the combination of ENBREL and methotrexa...

LABA Drugs Dangerous In Asthma

...y LABA drugs. LABA on its own is not safe and this monotherapy is neither supported by current evidence nor encouraged by the current British Thoracic Society guidelines," Vassiliou wrote. The US Food and Drug Administration issued a warning last year that LABA drugs may be related to asthma-linked deaths. “It...

Combination Therapy More Effective for Treating Lower Urinary Tract Symptoms

...ents receiving tamsulosin. Neither group receiving monotherapy demonstrated significant differences vs. placebo i... overactive bladder symptoms, might not respond to monotherapy with either ?-receptor antagonists or antimuscarinic agents. Treatment with tolterodine ER plus tams...

Statin Therapy Cuts Bad Cholesterol Unprecedented 70 Percent

...ith 29% with Crestor monotherapy. * Both CRESTOR monotherapy and CRESTOR combined with ezetimibe produced similar increases in HDL-C (“good” cholesterol) (8.5% vs. 10.8%). * CRESTOR and ezetimibe were both well tolerated. ** EXPLORER (Examination of Potential Lipid modifying effects Of Rosuvastatin in com...

FDA Decision Encourages Lamictal Generics

...ic patients. It is also approved for conversion to monotherapy in adults with partial seizures who are receiving treatment with a single enzyme-inducing antiepileptic drug or valproate. In addition, Lamictal is indicated for the maintenance treatment of bipolar I disorder in certain patients. Source-Bio-Bio T...

Combination Therapy More Effective Than Monotherapy for Treating Migraine

...perior to sumatriptan monotherapy, naproxen sodium monotherapy and placebo. The incidence of adverse events was s...atriptan–naproxen sodium compared with sumatriptan monotherapy might be explained by its targeting of multiple pathogenic mechanisms in migraine," the authors writ...

HIV Eradication Unlikely Following Bone Marrow Transplantation

...ght provide a more satisfactory outcome, since AZT monotherapy had been used in most cases (Huzicka 1999). Since then, however, other less toxic and/or invasive methods of HIV eradication have been attempted, and many different kinds of studies are ongoing. French investigators have now reported the first ...

Pazopanib Shows Positive in Advanced Renal Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

...pment program for pazopanib, in various cancers as monotherapy and in combination therapy, including combinations...an cancer study. This ongoing Phase II open-label, monotherapy study is evaluating pazopanib in patients with cancer of the ovary, fallopian tube or peritoneum, wh...

FDA Approves INTUNIV (guanfacine) for the Treatment of ADHD

...lets Shire is seeking approval of INTUNIV as monotherapy for the treatment of ADHD symptoms throughout the day in children aged 6 to 17 years, with dosage strengths of 1 mg to 4 mg daily. The INTUNIV New Drug Application (NDA) includes data from two placebo-controlled trials in children and adolescents age...

New Study Challenges NICE Guidelines on Adolescent Depression

...ation of SSRI and cognitive behaviour therapy over monotherapy for depression in adolescents, writes Professor Ph...ontrary to NICE guidelines, evidence suggests that monotherapy with an SSRI is a reasonable treatment option for moderate to severe depression in adolescents, part...

Alternative Option for Type2 Diabetes Treatment

...ibitor (a class of oral hypoglycemics), for use as monotherapy or in combination with other medications. The effectiveness of this class of medications in managing type 2 diabetes is not well understood. Renee E. Amori, M.D., of Tufts-New England Medical Center, Boston, and colleagues conducted a meta-analysis...

EpiCept Accelerates Development of Phase I Clinical Study for Cancer

... a Phase 1b trial is planned to follow the current monotherapy trial. EPC2407 is one of two VDA compounds currently in clinical trials discovered through EpiCept's Anti-cancer Screening Apoptosis Program (ASAP). The second compound, Azixa(TM), is part of the EP90745 series of apoptosis inducers, which was licens...

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