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Tag: "monoclonal" at medical news

Lymphoma Patients Maybe Helped by Adding Radioimmunotherapy to Chemo

...py was delivered through the use of a radiolabeled monoclonal antibody specifically designed to kill lymphoma ce...oactive atom. We found that adding a radioactive monoclonal antibody to standard chemotherapy helped lymphoma patients achieve a higher complete response rate. ...

Medarex Announces Collaborative Research Agreement With Mitsubishi Pharma

...panies expect to generate and evaluate fully human monoclonal antibodies against a Mitsubishi target for the potential treatment of autoimmune diseases. The companies plan to use Medarex's UltiMAb Human Antibody Development System(R) to generate antibodies for research and possible development. Under the term...

Peregrine Pharmaceuticals Initiates Patient Enrollment In New Cotara(R) Brain Cancer Trial

...tage biopharmaceutical company developing targeted monoclonal antibodies for the treatment of cancer and hepatitis C virus infection, today announced initiation of a new clinical trial designed to evaluate the safety and efficacy of its tumor necrosis therapy (TNT) agent Cotara(R) in patients with glioblastoma...

New Adjuvant Breast Cancer Treatments Found Cost-effective

...ast cancer, the addition of the anti-HER2 receptor monoclonal antibody, trastuzumab (trade name: Herceptin), is projected to improve life expectancy at a comparatively low cost. Breast cancer is a major cause of cancer mortality, second only to lung cancer as a cause of cancer death in women. The five-year sur...

Cost-effective Treatments for Breast Cancer

...ast cancer, the addition of the anti-HER2 receptor monoclonal antibody, trastuzumab (trade name: Herceptin), is ...gical treatments, including hormone modulators and monoclonal antibodies. Many of these agents have led to decreased mortality and disease recurrence. As the ther...

Untreatable Eye Disease Improves With Avastin

... for macular radiation retinopathy. Avastin is a monoclonal anti-body which inhibits the formation of abnormal blood vessels by selectively blocking a substance known as vascular endothelial growth factor (VEGF). Avasitin (also called bevaciaumab) is used systemically (throughout the body) for some cancers an...

Humanized Antibody Therapy Found Highly Effective in Easing RA Symptoms

...umanised anti human interleukin 6 (IIL-6) receptor monoclonal antibody, a cytokine involved in the pathogenesis of RA....

Researchers Find New Target for Anti-cancer Drugs

...e. A biotechnology company has already developed a monoclonal antibody specific to IL-6 which could be used to n...ize IL-6. A phase II trial is underway testing a monoclonal antibody against IL-6 for patients with multiple myeloma, a cancer that depends on IL-6 but is not k...

Monoclonal Antibody Induces Death in Liver Cancer Cells

...hool of Medicine have found that a newly available monoclonal antibody has the potential to induce death in liver cancer cells. In a study, the monoclonal antibodies' use demonstrated significantly reduces tumour cell proliferation and survival in human ...

A New Monoclonal Antibody Kills Cancer Cells

...lar Cancer Therapeutics. Using a newly available monoclonal antibody, they demonstrated significant reductions...ted human and mouse liver cancer cell lines with a monoclonal antibody targeted against PDGFR alpha. It resulted in a significant decrease in tumor cell prolifera...

Roches Arthritis Drug Successful in III Stage Trail

...toms. Biologic Actemra (tocilizumab), a humanized monoclonal antibody works by a different mechanism than today's rheumatoid arthritis treatments. Actema is the first biologic to inhibit the interleukin-6, or Il-6, receptor. IL-6 is considered an important mediator of the acute inflammatory response. Sufferer...

Study Confirms Benefits of Chemo, Trastuzumab Combo to Battle Breast Cancer

...creased response to treatment. Trastuzumab is a monoclonal antibody that directly targets part of the HER2 tyrosine kinase receptor. The results showed that combining trastuzumab with chemotherapy results in a 34 percent reduction in mortality and a 38 percent increase in disease-free survival, Dahabreh sa...

Combination of Tratuzumab and Chemotherapy Yields Better Results for Breast Cancer

... decreased response to treatment. Trastuzumab is a monoclonal antibody that directly targets part of the HER2 tyrosine kinase receptor. The results showed that combining trastuzumab with chemotherapy results in a -34% reduction in mortality and a 38% increase in disease-free survival, Dahabreh said. Those sur...

Biologics valuable treatment option for patients with inflammatory bowel disease

...Europe. The conference examined the literature on monoclonal antibodies or antibody fragments currently approved by the FDA or likely to be approved in the near future. The participants of the Consensus Development Conference, medical experts in IBD convened by the AGA Institute, sought to answer a series of q...

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