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Tag: "monoclonal" at medical news

New drug helps boost cancer treatment

...ients. IMC-C225, the new drug which is actually a monoclonal antibody, is designed to interfere with the epider...ectal, head, neck, pancreatic and lung cancer. The monoclonal antibody was well tolerated by the patients. The most common side effect attributed to the drug was ...

Experimental SARS Vaccine

... of SARS prevention, known as a neutralizing human monoclonal antibody, in ferrets that were also deliberately infected with SARS. Results showed the animals had significantly reduced levels of the virus in their lungs and did not develop any SARS-induced lung damage. Researchers say, though further studies ar...

Transplanted heart made more acceptable by daclizumab

...standard immunosuppression. The drug, a humanized monoclonal antibody, is directed against the interleukin-2 receptor, thereby inhibiting T-cell proliferation. Patients who were taken into the Study were either given daclizumab or a placebo. The primary endpoint was a composite of moderate or severe cellular...

Fighting against disease as easy as eating eggs

...anism. Anti-bodies produced this way are called as monoclonal antibodies. With advances in the field of immunolo...s to fight specific invaders. First, the specific monoclonal antibody that has to be produced is inserted into chicken embryonic stem cells along with the genes ...

Therapeutic Monoclonal Antibody Production Is More Profitable Than Small Molecule Drugs

New study has suggested that therapeutics based on monoclonal antibodies (mAbs) are fare more likely to be commercially successful than their small molecule predecessors. According to a study completed by // consultancy Propagate Pharma, about half the mAbs launched so fare appear to be profitable. That means m...

Monoclonal antibodies show promise in treatment of blood cancer

...ke University Medical Center have found that a new monoclonal antibody that targets immune system B cells could ...tory are the co-authors of this report. Basically, monoclonal antibodies are directed against specific proteins. In this study, the Duke researchers targeted a su...

Stem Cells Can Be Used To Kill Cancer Cells

...tudy by Duke University researchers who found that monoclonal antibodies could be used to treat several types of leukemias, autoimmune diseases and transplant rejections. In the present study, researchers were also able to accurately study how the immune system woks when confronted with unknown invaders. "We ...

Novel Actemra monotherapy in treating patients with early aggressive rheumatoid arthritis

...humanized anti-human interleukin-6 (IL-6) receptor monoclonal antibody. A monoclonal antibody is used to denote antibodies derived from genetically identical group of cells, a clone. Th...

Patients More Willing To Use Self-Injectable HIV Therapy Than Anticipated

... integration of other new innovative drugs such as monoclonal antibodies that are increasingly being developed for the management of HIV and other diseases. The study was conceived to look at attitudes to FUZEON (enfuvirtide), the first approved HIV fusion inhibitor, and an important option for treatment-expe...

Herceptin for Early Stage Breast cancer

...ogen therapies). The Drug Herceptin is a humanized monoclonal antibody prepared for treating Her-2 positive patients but the drug is very costly and the Herceptin treatment is to be given for 1 year. Herceptin is approved for late stage breast cancer treatment but a new study conducted by Breast Cancer Intern...

Treatment of Breast Cancer with Herceptin for Nine Weeks

...nts the risk of heart problems.// Herceptin is a monoclonal antibody that attacks the HER-2 protein that is highly expressed in about 30% of the breast cancers. The results of the combination therapy (Herceptin + anthracycline-based chemotherapy) were better when compared to chemo alone. A study was condu...

Epstein - Barr virus Protein Implicated in Blood Cancer

...rontline drug for treating B cell lymphoma, a CD20 monoclonal antibody." The researchers surmise that the first use of future therapies from these studies could be in lymphoproliferative disease in transplant and immunocompromised patients." Contact: Karen Kreeger karen.kreeger@uphs.upenn.edu 215-349-5658 Uni...

Monoclonal Anti-Body To Revolutionize Brain Cancer Treatment

The use of monoclonal anti-body (mAb) L2G7 could revolutionize treatment...evised to test the effectiveness and safety of the monoclonal anti-body in the glioma treatment. Implantation of L2G7 under the skin was found to produce complete...

Regulators Object Drug Produced from Genetically Engineered Farm Animals

...such types of biotechnology drugs. Cancer-fighting monoclonal antibodies and many such drugs are produced using cultures of genetically engineered animal cells. These factories are a very expensive proposition costing several hundred million dollars for each factory. Many other protein drugs, similar to the ...

Drug Firm Disowns Liability

...effects may be encountered during any trial with a monoclonal antibody drug, though they did not occur even at the highest tested doses in animals. The various side effects listed are immunosuppression, autoimmunity, cytokine release, and anaphylaxis. Even the Medicines and Healthcare Products Regulatory Agency...

Biocon To Shift Focus On Innovation To Accelerate Growth

...he company is gearing up to manufacture a range of monoclonal anti-bodies and other recombinant therapeutic products. "We have completed registration enabling clinical trials for our therapeutic drug (BIOMAb EGFR) to treat neck and head cancers. Investigational new drug application (IND) for diabetes oral i...

Kalam Dedicates New Cancer Drug Developed By Biocon

...congratulated Biocon scientists for developing the monoclonal antibody, BioMab EGFR (epidermal growth factor rec... Company executives said though a large number of monoclonal antibodies have been launched in the country, they are beyond the reach of a majority of cancer pati...

New Multi-Modal Contrast Agents, A Boon For Medical Imaging

...we put a ligand -- an organic substance, such as a monoclonal antibody -- on the outside that searches out in the bloodstream. Antibodies seek their antigens. So we target something to seek out a substance that's expressed by cells -- cancer cells, in my work. Cancer cells express particular antigens to which a...

New Molecular Treatment Identified To Treat Blood Cell Cancers

...a tumors in mice. LLP2A is intended to work like a monoclonal antibody – but a peptide is much smaller than an a...es or anti-cancer drugs directly to a tumor. Three monoclonal antibodies, rituximab (Rituxan), ibritumomab tiuxetan (Zevalin), and tositumomab (Bexxar), have alre...

Cuba Registers New Antibody

...nology (CIGB) has registered the first recombinant monoclonal antibody to be used in the production of an anti-h...d nations. Baptized as CB-Hep.1, the recombinant monoclonal antibody made of plants is of great relevance to increase the production of the anti-hepatitis B vac...

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