Genetic Pathways to Curable and Incurable Forms of Pancreatic Cancer Identified
...genetic reason why. Using unique mouse models to mimic the progression of both forms of human pancreatic cancer, researchers have discovered that a specific sequence of otherwise common genetic mutations is responsible for sending cells down the less-traveled path toward cystic pancreatic cancer versus t...Estradiol Guards Against Osteoporosis
... other pharmacological or nutritional agents might mimic or aid this action of estradiol." Source-Eurekalert PRI...Micro-jets for Painless Needle-free Injections
... dose, and can be delivered in quick succession to mimic a standard injection, or delivered slowly over a period of time in a similar fashion to a conventional transdermal delivery system. The device could also be developed to incorporate multiple nozzles to facilitate higher doses. Using insulin as a ...Obesity And Environmental Chemicals: Research Probes Potential Link
... on gene expression. Does exposure to PBDEs, which mimic estrogen and thyroid hormones in the body, make cells more likely to develop into fat cells? “Everything I do has to do with how changes in signaling result in changes in gene expression,” she says. Carey’s work is at the cellular level. Isolating...Natural Antibiotics Yield Secrets to Atom-level Imaging Technique
... fungi and even cancer cells, so drugs designed to mimic them could have widespread medical applications, said Ramamoorthy, who is an associate professor of chemistry and an associate research scientist in the Biophysics Research Division. While researchers have identified hundreds of AMPs in recent year...Max Planck Researchers Incorporate Odorant Receptors into Artificial Membranes
...proteins to artificial lipid membrane systems that mimic natural cell membranes from a statu nascendi, and the membrane proteins actually did simply insert themselves into the artificial membranes. The odorant receptors selected by the researchers were a type of G-protein coupled receptor taken from brown ...Natural Brain Substance Linked to Parkinson's Symptoms
...ed and recorded when the mice were given toxins to mimic the symptoms of Parkinson's. The mice were administered a drug combination - potentially a precursor of a human experimental therapy - to test the main findings. One drug, called quinpirole, boosted dopamine - a standard medical strategy in human c...Food Odors Linked With Lifespan in Fruit Flies
... pharmaceutical companies would like to be able to mimic the beneficial effects of caloric restriction by h... pharmaceutical companies would like to be able to mimic the beneficial effects of caloric restriction by having you take a pill. But for that to work, you n...A Novel Technique Nudges Genes Into Activity
...which they interact with the chromosome appears to mimic what naturally happens in the body. "One of the reasons why these synthetic strands work so well is that we’re just adapting a natural mechanism to help deliver a man-made molecule," Dr. Corey said. "We’re working with nature, rather than against i...UIC Researchers Receive $2.1 Million Grant
... inhibit the enzyme glycogen synthase kinase-3 may mimic the therapeutic action of the mood stabilizers, Kozikowski said, and might point the way to the design of improved drugs for treating patients with bipolar disorder. More than 2 million American adults, or about 1 percent of the over-18 population,...Allergic Reactions to Insulin Have Declined
...rd to the arrival of newly designed molecules that mimic the action of insulin while avoiding triggering an allergic response. In addition new modes of drug delivery, such as continuous subcutaneous insulin infusion (CSII), may help, and early reports suggest that CSII can help people who have previously h...MIT Creates 3-D Scaffold for Growing Stem Cells
...ffolds have been studied for more than 30 years to mimic a living 3D microenvironment, but concerns exist about their degradation products and chemicals," the authors wrote in the paper. Other synthetic polymer biomaterials are simply too big. Getting cells to grow on them is like forcing spiders to buil...Molecular ‘On/Off Switch’ Controls Immune Defenses Against Viruss
.... “This knowledge will help us design drugs that mimic the viral effects on these proteins to either acti... to design novel therapeutics and drugs that could mimic viral effects on RIG-I to spur antiviral response or, conversely, mimic viral effects on LGP2 to shu...Research on Bipolar Disorder Launched
...BPD is tough, though, because some of the symptoms mimic emotions and behaviors that are initially thought to be typical of children. Unlike normal mood changes, however, bipolar disorder significantly impairs functioning in school with peers and at home with family. Diagnosis is also hampered by the sympt...Stem Cell Activity Deciphered in the Aging Brain
...ored is to treat older rats with drugs designed to mimic the action of compounds called neurogenic factors, which encourage stem cells in the brain to divide, Shetty said. The researchers also are grafting neural stem cells grown in culture dishes into the hippocampus, to stimulate those already present. A...'Clumping' Protein Linked to Return of Ovarian Cancer
...tal mice. Shih says that in the future, drugs that mimic N130 can be used to treat cancer. Source-Newswise SRM...Video Games Fun but Pose Social, Health Risks
... a game that requires players to dance on a mat to mimic moves they see on their TV, elicits the same level of motion in children as other forms of exercise. But the game is a solo activity, Storch said. Dancing with friends or playing sports would get kids moving and give them a chance to spend time with ...Majority Of Doctors Tend To Ignore Milk Allergy Cases In Babies
...he high content of phytoestrogens - compounds that mimic the action of the female hormone oestrogen. This could pose a risk in the long - term reproductive health of infants and also by causing allergies to both kinds of milk in infants. Jane Bell, 34, mother, who lives in London with police officer hus...Medically Induced Abortions (MIAs) Causes More Deaths Due To Infection
...ifficult to identify and, in the early stages, can mimic other, more common infections. Both authors stress the need for further research to discover the factors that predispose to these infections so that preventive measures can be designed. Source-Eurekalert SRI...