Gene enchances radiation therapy - A novel approach to fight cancer
... The researchers in their experiment injected the mice with mutant form of EGFR, called EGFR-CD533 that p...and then they irradiated them. They found that the mice that had received the gene therapy had a nearly threefold decrease in activation of the EGFR repair ...Dissecting Diabetes - Is protein AKT2 the cause of type 2 diabetes?
...iabetes mellitus. They have discovered that mice lacking a gene that produces the enzyme called Akt...studies showed that the liver of the Akt2 knockout mice did not respond to insulin by lowering glucose production, and their tissues were consuming less glu...And now its super mice for longer memory
...n a landmark breakthrough, scientists have created mice with unusually long memories raising hopes of peop...nd French scientists conducted this study in which mice were created with a gene that blocks the function of a signaling protein called calcineurin in the b...Protein causing spread of colon cancer identified
... They are also hoping to inject tumour cells into mice from which the protein has been removed, to check if the tumour cells still spread to the liver.......ona journal say that a gene has been identified in mice which, if absent, causes symptoms remarkably simil...and lungs. The investigators from UCSD,found that mice with a genetic mutation in an enzyme called alpha-mannosidase II develop lupus-type symptoms. This e...Limiting sperm motility for contraception
...ut the gene in mice. They found that, although the mice were normal in every other respect, and that female mice were fertile, the male mice were completely infertile. Studies of the sperm motility of the mice we...Fat Cell Protein Hits Type-2 Diabetes
...an exact copy of the Acrp30 protein. They injected mice with Acrp30 until they doubled the protein level. The question was that iIf we simply doubled the concentration of this adipose-derived hormone and then carefully measure the hepatic glucose production -- or action of insulin on the liver-- are we g...New Stem Cells lines will be required
...lls and serum" creating the fear that pathogens in mice or cows could be transmitted to humans if the stem cells are used for therapeutic applications. Another problem is that patient's immune system may attack the newly introduced stem cells. One way of sidestepping the problem is through a process know...Breakthrough in Type II Diabetes
...iabetes mellitus. They have discovered that mice lacking a gene that produces the enzyme called Akt...studies showed that the liver of the Akt2 knockout mice did not respond to insulin by lowering glucose production, and their tissues were consuming less glu...Research in mice has drawn a direct link between a human gene and t...cology in Sweden found that genetically engineered mice with a mutation in the gene, known as Cdk4, were more likely to develop melanomas when exposed to ca......rnia and Gladstone developed strains of transgenic mice that produce two human proteins – human amyloid pr...ed with Alzheimer’s and hSYN with Parkinson’s; and mice that produce one of these proteins develop the symptoms of the associated disease. The researchers...Mystery of nacrolepsy uncovered
... Howard Hughes Medical Institute in Dallas created mice that were incapable of making hypocretin. They discovered that the animals could not stay awake. It also seems likely that environmental factors may play a role in the condition. One identical twin may suffer from the condition, while the other may n...Genetic failure in cloned animals
.... Jaenisch's team looked at 5,000 genes in cloned mice and found hundreds of genes important to development were not correctly expressed in the animals, he said. Overall, about one out of every 20 genes was not expressed correctly in the placenta. Abnormal gene expression also was observed in the liver b...Primates reveal a new dimension to human genome
...se of time. There is a huge time lapse between the mice and humans since they shared common ancestors, which makes it difficult to compare them. But primates were comparatively recent in sharing common ancestors, and hence it is more easier to make a comparative study. Consequently, non-human primates ha...An Enzyme That Turns a One –time Experience into a long-time Memor
... C.// Researchers in New Orleans studied female mice and how they remembered their mating partner. They...covered that with only one exposure at mating, the mice can later recognize their partner’s scent. After mating, a female mouse exposed to the scent of a st...Hope For Patients With Muscular Dystrophy
... 1997. They found “knocking out” the gene produced mice with muscles that were twice as large as those of ...gents already known to block myostatin activity in mice may be able to increase muscle mass in humans too....SNUPPY – Woo Suk Hwang reveals World’s first dog cloe
... cells. Stem cells can currently only be cloned in mice and human cells. “Once stem cells can be established it may be possible to learn about the genetic basis of traits by studying cells in a dish rather than in the dogs themselves,” he says. But despite Schatten’s warning, many people are likely to im...Enzyme Responsible For Congenital Blindness
...he blindness in these children, as was observed in mice and dogs with RPE65 mutations, said the researchers. This is a major breakthrough in understanding the visual cycle. It has ramifications for several inherited blinding diseases caused by mutations in visual cycle genes. The newly identified isomera...A Protein That Increases Risk Of Tumours
...at the protein encourages the growth of tumours in mice exposed to a carcinogen, reports the science porta...ethane, a lung-specific carcinogen, on two sets of mice -- wild-type mice, which have two functional genes that express Bcl-xL, and transgenic mice that hav......as also found to encourage the growth of tumors in mice following exposure to a carcinogen. The study comp...in, developed less number of tumors in contrast to mice that produced more of Bcl. Moreover, mice with more Bcl protein production on an average had larger ...