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Tag: "mice" at medical news

Discovering cholesterol-absorbing genes

According to researchers in a recent study on both mice and humans are showing why some people absorb more...ersity have been working with genetically modified mice to discover the genes for cholesterol absorption. They have narrowed their search to two distinct re...

Fireflies help speed development of new drugs

...sible for the firefly glow-producing molecule into mice with cancer. The researchers kept the molecule fro... highly sensitive camera to detect the glow in the mice as the cancer cells were destroyed by the drugs which was being tested. Researchers concluded that ...

Myostatin gene could hold the key to treatment for DMD

...published online, that muscle mass and strength in mice with DMD is increased by the loss of the myostatin...opkins geneticist Se-Jin Lee to create a strain of mice lacking the myostatin gene which were later bred with mice with DMD. They found that the offspring h...

Treatment for cholesterol-related illnesses likely with the discovery of receptor in mice

...r with the discovery of a receptor in the cells of mice that protects them from toxins. Researchers discovered the receptor during a study of cerebrotendinous xanthomatosis (CTX), a rare and often fatal disorder caused by excessive cholesterol metabolites. They said that Pregnane X receptor (PXR)// is pre...

Stroke victims have new hope with activated protein C

... by stroke. Researchers who conducted the study on mice found that APC could protect brain cells from the ...neurological deficits by 91 per cent when given to mice following a stroke. Currently, only tissue plasminogen activator is useful for the 80 per cent of st...

Mental retardation linked to brain protein

...ell communication. The research was carried out on mice that were produced, without the WAVE-1// protein, by the researchers . It was found that these mice had balance, motor, learning and memory problems and the symptoms in these mice without WAVE-1, corr...

Scientists locate key hormone involved in appetite control

...search has shown that increasing ghrelin levels in mice for an extended period resulted in weight gain. Gh...h informs the brain when it's time to eat. In both mice and humans, ghrelin levels increase naturally in response to weight loss or reduced caloric intake a...

Gene defect linked to dilated cardiomyopathy(DCM)

...ankles becoming swollen. Scientists used tests on mice to determine if a defect in this gene is enough to trigger DCM. They found that a mouse with a defect on the phospholamban gene also suffered severe damage to its heart. Further laboratory tests also showed that this defect disrupts the calcium pump ...

Liver cancers which spread are linked to a particular gene

...tein prevents cancer cells from spreading, both in mice and in the laboratory. Osteopontin can be used as a diagnostic marker, as it is found in all body fluids and, drugs that block the protein may help contain liver tumors that spread....

Blindness can be stopped with drug for acne treatment

...tops the accumulation of lipofuscin in the eyes of mice with Stargardt's macular degeneration. Upon examination of the mice after two months of treatment with Accutane, the side effect of which includes night blindness, the ...

Cells critical for asthma development found

Researchers have found that mice lacking a specific immune cell are unable to devel...earchers at Stanford University have been studying mice that lack a specific type of// immune cell called natural killer (NK) cells. These mice do not get a...

Adult stem cells in treatment for Multiple sclerosis (MS)

...und that treatment with adult stem cells has cured mice suffering with a form of multiple sclerosis. While...wed improvement. Researchers injected the diseased mice with stem cells extracted from the brains of adult in the bloodstream or spinal cord. On examination...

Diabetes Cure With Gene Therapy

...apy developed by researchers has cured diabetes in mice by inducing cells in the liver to become beta cells that produce insulin and three other hormones. The researchers used NeuroD gene which induces the liver to produce cells that make insulin and hormones relating to pancreas. NeuroD partially cured d...

Virus Helps Remove Brain Cancer

...und in repeated experiments that more than half of mice that had human glioblastoma tumors implanted in th...vived for more than four months, whereas untreated mice lived for less than three weeks. Many experiments have been conducted since this study and they all ...

Enzyme help destroy cancer cell

...cells directly. When experiments were conducted on mice researchers identified an cell suicide enzyme, getting activated when struck by radiation. This enzyme destroys tumor nourishing blood vessels to die. Tumors cannot survive without oxygen and nutrient supply. While it was thought that damage to the D...

Lithium May help in Alzheimer's Disease

...t issue of the journal Nature has reported that in mice experiments, Lithium blocks the production of proteins that form deposits in the brains of Alzheimer's patients. Lithium, though widely used to treat mental problems does have many side effects, including kidney damage. "Potentially, lithium could ...

Hope for First New Melanoma Treatment in Decades

... temporarily switched off the tumor cell growth in mice and allowed apoptosis, or cell death normally occurring in non-cancerous cells, to resume. Apoptosis made the cells behave more like normal cells, thereby clearing away the dysfunctional and damaged cells. Of the three forms of skin cancer, melanoma...

New target for antidiabetic agents identified

...f TRB3 RNA and protein were identified in diabetic mice compared with wild-type mice, the authors report. Hepatic overexpression of TRB3 was associated with hyperglycemia and glucose intolerance. Based on these findings, the researchers suggest that TRB3 may be an "attractive drug target in the treatment...

Vitamin D Wipes out Cancer Cells

...east cancer.Investigators compared tumor growth in mice treated with radiation alone to mice exposed to both radiation and EB 1089, a derivative of vitamin D. After treatment, the tumor volume ...

Gene Mutation Causes Ovarian Failure

...ery 100 women ages 30 to 39. Investigators created mice that lack both copies of a gene called FOXO3a, whi...to aging, cancer and diabetes. As the gene-altered mice aged, the females had fewer and smaller litters. By 15 weeks, which is comparable to early adulthood...

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