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Tag: "mice" at medical news

Enzyme may be target for obesity drugs

...icoids. Alteration in the levels of this enzyme in mice produces not only obesity, but obesity especially of abdominal fat. Since this enzyme is known to be similarly elevated in the fat of obese people, it is very likely that the same pathway is involved in many cases of human obesity. Blocking the enz...

Early delivery can prevent cancer

... against breast cancer. In experiments, rats and mice given doses of natural hormones that mimic pregnancy were protected against breast cancer. When the animals were injected with a known carcinogen, they did not develop as many mammary tumours as expected. The research was carried out by a team at Bay...

Alcohol within the body

... the liver. Dr Diehl's team tested the theory on mice genetically engineered to be obese. The mice were fed on a diet that did not contain alcohol, and breath samples were taken as they aged. Obesity...

Cinnamon combats Diabetes

...halcone polymer (MHCP), and unpublished studies on mice found that abnormally high glucose concentrations in diabetic mice fell dramatically when given MHCP. Clinical trials of this chemical are due to begin within a year, ...

A new study surpasses Gene Therapy Hurdle

...rred into human blood stem cells and injected into mice that were bred so they would not reject the human cells. After 9 weeks, Chengh felt that the researchers looked at all the cells descending from the stem cells and found only the APCs showed the green fluorescence. This is a green light for regulated...

Nose plug-switch that stops smelling

...lly engineered mice, one research team showed that mice lacking CNGA4 could sense odours but could not adapt to them.Other scientists studied the molecule’s behaviour in laboratory-grown cells and reported that CNGA4 speeds up the ‘nose’s closing. Without CNGA4, the closing took 100 times longer...

Vitamin E useful for Alzheimer's

...age they cause. The study has been carried out on mice with stupenduous potential.Oxidative stress is caused by the toxic effect of highly reactive oxygen molecules, called free radicals, which damage cells and DNA. Growing evidence shows it may be responsible for certain progressive neurodegenerative di...

Heriditary dental disorders

...lkarni and his colleagues genetically// engineered mice that make extra amounts of TGF-b1 (transforming growth factor beta-1) in their teeth. The animals were born with no apparent defects, but at two weeks their teeth became discolored and eventually fractured, leaving behind small stumps. Specialized st...

WBC linked with periodontitis

...t at six weeks of age the// genetically engineered mice had lost 27 percent of their alveolar bone whereas the normal mice had no bone loss. The loss of alveolar bone, which anchors teeth in place, is an indication of peri...

Nose plug: switch that stops smelling

...lly engineered mice, one research team showed that mice lacking CNGA4 could sense odours but could not adapt to them. Other scientists studied the molecule’s behaviour in laboratory-grown cells and reported that CNGA4 speeds up the ‘nose’s closing. Without CNGA4, the closing took 100 times longer....

Experimental drug to fight flu

... dose of multimeric zanamivir successfully treated mice infected with human influenza A and B....

Blood test may aid foretell Alzheimer's

...s, a novel blood test can detect plaque buildup in mice brains, suggesting a possible new way to predict w...aque later in life. The St. Louis team examined 40 mice carrying a genetic mutation to develop buildup up amyloid plaque. Two types of this amyloid protein ...

Pill may replace exercise

... study, Williams and colleagues created a group of mice with genes that made a surplus of a protein called calmodulin-dependent protein kinase, or CaMK. When this protein is activated, it and another protein, calcineurin, trigger the physical changes that muscle cells undergo after intense exercise....

Leptin connected to obesity blood clots

...ing the blood clot more easily. Experiments with mice have shown that leptin-deficient mice have clotting times twice as long as normal mice. And mice with a deficiency in the leptin receptor ...

Leptin linked to Blood Clots

...s in mice. Eitzman looked at a group of overweight mice that were genetically engineered to lack the gene ...70 minutes to clot, almost twice as long as normal mice who clotted at 40 minutes. Blood clotting capabilities were tested on another group of mice missing...

Clotting Protein plays a role in nerve repair

...in. The researchers made the discovery by studying mice that lacked the protein. After an injury to the sc...yelin regenerated much more rapidly in fibrin-free mice than in normal mice. Strickland's team describes fibrin's role in the repair process--at least outs...

Stem Cells Have Few Mutations

...t common embryonic stem cell mutation found in the mice was the deletion of a chromosome that is replaced ...han are human stem cells and that what is found in mice often does not apply to humans....

Changing stem cells to liver cells

..., for the first time, that stem cells from humans, mice and rats can be turned into functioning liver cells. A team at the University of Texas have been able to treat adult bone marrow stem cells so that they become liver cells.// These cells look, stain and function like authentic liver cells. They produ...

How to repeal male infertility?

...ings from an animal study that show infertile male mice treated with gene therapy are able to go on to produce offspring.// According to researchers, up to 30 percent of couples worldwide are infertile. Between 20 percent and 40 percent of these are due to male infertility and the majority of those are a...

Important substance in curry conciliate Inflamed Colon

... induced severe colitis, or colon inflammation, in mice using a chemical and immediately gave the mice a diet containing 1% to 2% curcumin for a week. The mice are used to study inflammatory bowel diseas...

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