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Tag: "methotrexate" at medical news

China Cracks the Whip Against Drug Manufacturers Who Fail Quality Norms

...g Administration said it had suspended the sale of methotrexate made by Shanghai Hualian Pharmaceutical Co. Ltd. ...ifficulty in walking after being injected with the methotrexate drug numbered 070403A and 070403B," the statement said. "Local drug regulators have been ordered t...

China Bans Sales of Leukemia Drug in Latest Medicine Scare

...g Administration on Saturday suspended the sale of methotrexate after children being treated for acute leukemia reported feeling pain and had difficulty walking after being injected with the drug, Xinhua news agency said. The medicine is also used to treat rheumatoid arthritis, it said. The watchdog ordered f...

Roches Arthritis Drug Successful in III Stage Trail

...en in combination with a standard treatment called methotrexate in patients who had an inadequate response to a relatively new type of drugs known as anti-tumor necrosis factor therapy, or anti-TNFs. The treatment showed a significant improvement in disease signs and symptoms. Biologic Actemra (tocilizumab), a h...

Humanized Antibody Therapy Found Highly Effective in Easing RA Symptoms

...A), who receive tocilizumab in addition to ongoing methotrexate therapy , showed a 50 per cent improvement in the ... subjects were permitted concurrent treatment with methotrexate at their pre-study dose, though treatment with all other disease modifying anti-rheumatic drugs was ...

Aging Gracefully, With a Chronic Disease

...and disease-modifying antirheumatic drugs, such as methotrexate and tumor necrosis factor (TNF) blockers. Exercise, weight loss and diet changes also can be helpful, Fox says. RA is one of more than 100 varieties of arthritis, a wide-ranging set of conditions that affects 70 million people in the United States....

Denosumab Reduces Bone Erosion

...of bone erosions in patients with RA on background methotrexate (MTX standard RA treatment). Mean erosion scores were significantly reduced for the groups treated with denosumab compared to the control group. Change in mean erosion score at 12 months was reported as 0.33 and 0.19 for treatment with denosumab 6...

New Drug for Rheumatoid Arthritis Looks Promising.

...hieved better clinical results in combination with methotrexate than when used as monotherapy. Currently available drugs that target a protein called tumour necrosis factor, or TNF, have helped revolutionise treatment for rheumatoid arthritis, but up to 40 percent of patients do not get an adequate response. TNF...

Carbon Nanoneedles For Drug Delivery

...h as amphotericin B (an anti-fungal treatment) and methotrexate (an anti-cancer drug) using the functionalised carbon nanotubes, but encountered some obstacles with drug release along the way. ”Once you chemically conjugate the drug on the nanotube, the drug is not capable of leaving the nanotube,” Dr Kostarelos ...

Adalimumab Proves Effective for Children with Juvenile Rheumatoid Arthritis

...ts were categorized as those taking and not taking methotrexate at the beginning of the study. The dose of methotrexate and all other arthritis medications remained stable throughout the trial. Adalimumab doses were base...

Chemo drugs cause cognitive decline in breast cancer patients

...he drug treatment group received standard doses of methotrexate and 5-fluorouracil (5FU), two drugs widely used in...t the adverse effects of this treatment regimen of methotrexate and 5FU probably do not extend to all regions of the brain. It appears that the hippocampus and fron...

RA Drugs Not Implicated In Cancer

...r than therapy with a standard prescription DMARD, methotrexate (MTX). The researchers focused on 7,830 RA patients, age 65 and older, drawn from healthcare databases in New Jersey, Pennsylvania, and British Columbia, Canada. Subjects included 1,152 biologic DMARD users and 7,306 MTX users. Of those treated wit...

NICE supports application of advanced biological therapies as treatment option for acute psoriasis

... to other systemic therapy including cyclosporine, methotrexate or PUVA (Psoralen (a light-sensitizing medication) combined with exposure to ultraviolet light A (UVA). Enbrel is also approved for the treatment of active and progressive psoriatic arthritis in adults when the response to previous disease-modifying ...

Enbrel Joins with Methotrexate to Cure Rheumatoid Arthritis

... year TEMPO trial reports in addition to the usual methotrexate therapy, rheumatoid arthritis patients also benefi...ion of ENBREL and methotrexate. Subjects receiving methotrexate monotherapy during the 3-year double-blind TEMPO trial were switched to the combination of ENBREL an...

B-Cell Biologic Therapy Could Revolutionize Rheumatoid Arthritis Treatment

...r another placebo. All subjects received the DMARD methotrexate (MXT). All subjects were evaluated every four weeks for changes in the Disease Active Score (DAS), a 28-joint assessment for swelling and tenderness, as well as for overall disease improvement, with the goal of meeting the American College of Rheumat...

No Lymphoma Risk From Rheumatoid Arthritis Drugs

... anti-rheumatic drugs (DMARDS), including the drug methotrexate (anti-cancer drug). No increased risk could also be documented with use of steroids or NSAIDs. Surprisingly, the incidence of lymphoma in those who were given corticosteriods injections was the lowest, probably highlighting its role in cancer prevent...

Doctor Pleads Not Guilty

... patients he treated in 2001 with a high dosage of methotrexate is reported to have died as a result of this. Some of the drugs that he used are also not approved in the US. But many of his patients claim that their lives had been saved due to Shantha’s treatment, and where traditional drugs had failed. <br...

Georgia: Indian doctor's license cancelled

...reated the patient with a chemotherapy drug called methotrexate in doses so high they posed "an unreasonable and significant risk to the patient who subsequently died from complications caused by the methotrexate". The board said it had received a letter from Shanthaveerappa on Thursday acknowledging that he ha...

Rolling Stones Guitarist Wants Chemotherapy

...anti-TNF agents (etanercept) and chemotherapy drug methotrexate has been shown to be effective in the treatment of Rheumatoid ... www.medindia.net/News/ View_news_main.asp?t=ph&x=5841 Colgate To Develop Anti-Cancer Toothpastes And Mouthwashes Cancers on the molecular level, giving the patient a better cha...

Combination Therapy With ENBREL And Methotrexate Found Effective In RA Treatment

...anti-TNF agents (etanercept) and chemotherapy drug methotrexate has been shown to be effective in the treatment of...of the combination therapy, ENBREL monotherapy and methotrexate monotherapy revealed that ENBREL monotherapy had significant results when compared to monotherapy wi...

Socialization A Serious Trouble For Childhood Cancer Survivors

...e treated with CRT or combined CRT and intrathecal methotrexate (IT MTX) were more likely to report educational difficulties. Socially, cancer survivors reported no close friends and less often used friends as confidants. Children with brain tumors were more likely to report difficulties with friendships. Child...

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